ECFT_HELMI
ID ECFT_HELMI Reviewed; 266 AA.
AC B0TC89;
DT 31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 08-APR-2008, sequence version 1.
DT 25-MAY-2022, entry version 57.
DE RecName: Full=Energy-coupling factor transporter transmembrane protein EcfT {ECO:0000255|HAMAP-Rule:MF_01461};
DE Short=ECF transporter T component EcfT {ECO:0000255|HAMAP-Rule:MF_01461};
GN Name=ecfT {ECO:0000255|HAMAP-Rule:MF_01461}; OrderedLocusNames=Helmi_13630;
GN ORFNames=HM1_1411;
OS Heliobacterium modesticaldum (strain ATCC 51547 / Ice1).
OC Bacteria; Firmicutes; Clostridia; Eubacteriales; Heliobacteriaceae;
OC Heliomicrobium.
OX NCBI_TaxID=498761;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51547 / Ice1;
RX PubMed=18441057; DOI=10.1128/jb.00299-08;
RA Sattley W.M., Madigan M.T., Swingley W.D., Cheung P.C., Clocksin K.M.,
RA Conrad A.L., Dejesa L.C., Honchak B.M., Jung D.O., Karbach L.E.,
RA Kurdoglu A., Lahiri S., Mastrian S.D., Page L.E., Taylor H.L., Wang Z.T.,
RA Raymond J., Chen M., Blankenship R.E., Touchman J.W.;
RT "The genome of Heliobacterium modesticaldum, a phototrophic representative
RT of the Firmicutes containing the simplest photosynthetic apparatus.";
RL J. Bacteriol. 190:4687-4696(2008).
CC -!- FUNCTION: Transmembrane (T) component of an energy-coupling factor
CC (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF
CC transporter provides the energy necessary to transport a number of
CC different substrates. {ECO:0000255|HAMAP-Rule:MF_01461}.
CC -!- SUBUNIT: Forms a stable energy-coupling factor (ECF) transporter
CC complex composed of 2 membrane-embedded substrate-binding proteins (S
CC component), 2 ATP-binding proteins (A component) and 2 transmembrane
CC proteins (T component). May be able to interact with more than 1 S
CC component at a time (By similarity). {ECO:0000255|HAMAP-Rule:MF_01461}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01461};
CC Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01461}.
CC -!- SIMILARITY: Belongs to the energy-coupling factor EcfT family.
CC {ECO:0000255|HAMAP-Rule:MF_01461}.
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DR EMBL; CP000930; ABZ83988.1; -; Genomic_DNA.
DR RefSeq; WP_012282504.1; NC_010337.2.
DR AlphaFoldDB; B0TC89; -.
DR SMR; B0TC89; -.
DR STRING; 498761.HM1_1411; -.
DR EnsemblBacteria; ABZ83988; ABZ83988; HM1_1411.
DR KEGG; hmo:HM1_1411; -.
DR eggNOG; COG0619; Bacteria.
DR HOGENOM; CLU_056469_2_2_9; -.
DR OMA; MKAQMSR; -.
DR OrthoDB; 1479665at2; -.
DR Proteomes; UP000008550; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR HAMAP; MF_01461; EcfT; 1.
DR InterPro; IPR003339; ABC/ECF_trnsptr_transmembrane.
DR InterPro; IPR024919; EcfT.
DR Pfam; PF02361; CbiQ; 1.
PE 3: Inferred from homology;
KW Cell membrane; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..266
FT /note="Energy-coupling factor transporter transmembrane
FT protein EcfT"
FT /id="PRO_0000408989"
FT TRANSMEM 26..46
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01461"
FT TRANSMEM 47..67
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01461"
FT TRANSMEM 69..89
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01461"
FT TRANSMEM 116..136
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01461"
FT TRANSMEM 151..171
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01461"
FT TRANSMEM 192..212
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01461"
FT TRANSMEM 246..266
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01461"
SQ SEQUENCE 266 AA; 29288 MW; C4F6A5921CB761AD CRC64;
MLKDITLGQY VPLDSPVHRL DPRTKVIATL LFSIALFLLP TLRSVTLAGL PIIIAIVATR
LPIHYILRGI KPLWIFIVFT LLVHLLSTPG ETAVRLGPFA ITWEGLRQGA MVSQRLIWLY
AATSLLTLTT SPIALTDGLE LLLSPGKRIG LPVHEFAMMT SIALRFIPTL IEETEKIMKA
QSSRGADFDS GSLVARVKSL VPLMVPLLLS AFRRADELAM AMEARCYRGG EGRTRMRPLV
MSGKDYAVTV AVSGVFILIC LWKKAL