ECFT_LIMFC
ID ECFT_LIMFC Reviewed; 267 AA.
AC D8IIP4;
DT 31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 05-OCT-2010, sequence version 1.
DT 03-AUG-2022, entry version 49.
DE RecName: Full=Energy-coupling factor transporter transmembrane protein EcfT {ECO:0000255|HAMAP-Rule:MF_01461};
DE Short=ECF transporter T component EcfT {ECO:0000255|HAMAP-Rule:MF_01461};
GN Name=ecfT {ECO:0000255|HAMAP-Rule:MF_01461}; OrderedLocusNames=LC40_0952;
OS Limosilactobacillus fermentum (strain CECT 5716 / Lc40) (Lactobacillus
OS fermentum).
OC Bacteria; Firmicutes; Bacilli; Lactobacillales; Lactobacillaceae;
OC Limosilactobacillus.
OX NCBI_TaxID=712938;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CECT 5716 / Lc40;
RX PubMed=20639335; DOI=10.1128/jb.00702-10;
RA Jimenez E., Langa S., Martin V., Arroyo R., Martin R., Fernandez L.,
RA Rodriguez J.M.;
RT "Complete genome sequence of Lactobacillus fermentum CECT 5716, a probiotic
RT strain isolated from human milk.";
RL J. Bacteriol. 192:4800-4800(2010).
CC -!- FUNCTION: Transmembrane (T) component of an energy-coupling factor
CC (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF
CC transporter provides the energy necessary to transport a number of
CC different substrates. {ECO:0000255|HAMAP-Rule:MF_01461}.
CC -!- SUBUNIT: Forms a stable energy-coupling factor (ECF) transporter
CC complex composed of 2 membrane-embedded substrate-binding proteins (S
CC component), 2 ATP-binding proteins (A component) and 2 transmembrane
CC proteins (T component). May be able to interact with more than 1 S
CC component at a time (By similarity). {ECO:0000255|HAMAP-Rule:MF_01461}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01461};
CC Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01461}.
CC -!- SIMILARITY: Belongs to the energy-coupling factor EcfT family.
CC {ECO:0000255|HAMAP-Rule:MF_01461}.
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DR EMBL; CP002033; ADJ41523.1; -; Genomic_DNA.
DR RefSeq; WP_003681619.1; NC_017465.1.
DR AlphaFoldDB; D8IIP4; -.
DR SMR; D8IIP4; -.
DR GeneID; 61200557; -.
DR KEGG; lfr:LC40_0952; -.
DR PATRIC; fig|712938.3.peg.1867; -.
DR HOGENOM; CLU_056469_2_2_9; -.
DR OMA; MKAQMSR; -.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR HAMAP; MF_01461; EcfT; 1.
DR InterPro; IPR003339; ABC/ECF_trnsptr_transmembrane.
DR InterPro; IPR024919; EcfT.
DR Pfam; PF02361; CbiQ; 1.
PE 3: Inferred from homology;
KW Cell membrane; Membrane; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..267
FT /note="Energy-coupling factor transporter transmembrane
FT protein EcfT"
FT /id="PRO_0000408992"
FT TRANSMEM 30..50
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01461"
FT TRANSMEM 67..87
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01461"
FT TRANSMEM 110..130
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01461"
FT TRANSMEM 152..172
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01461"
FT TRANSMEM 247..267
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01461"
SQ SEQUENCE 267 AA; 29827 MW; 1D781079E8CE8619 CRC64;
MNSRVLFGSF VPVDSVLHRL DPRLKLVTCF WYVVIIFFAK GPLTYLLLVA MLGAMIGLSK
VPLKMYWAGL KPLLWVIGLT IAIQVLFSSG GHVYWHWGLM AITSGGINQA LVILARFILI
VLASTVLTAT TPPLRLADAI ESLMKPLKKI KVPVNQIAMM ISIALRFIPT IMDEVNTIVK
AQQARGVDFT SGSVYTRVKR MVPIMVPLFV GAFRRAEDLA VAMEARGYDP DQERTRYRQL
TWRRPDSIAL AVVVIVSVLF FVARILL
