ID   ECL2_SCHPO              Reviewed;          84 AA.
AC   C6Y4C5;
DT   24-NOV-2009, integrated into UniProtKB/Swiss-Prot.
DT   22-SEP-2009, sequence version 1.
DT   03-AUG-2022, entry version 53.
DE   RecName: Full=Extender of the chronological lifespan protein 2;
GN   Name=ecl2; ORFNames=SPBP35G2.16c;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   FUNCTION, SUBCELLULAR LOCATION, AND INDUCTION.
RX   PubMed=19352039; DOI=10.1271/bbb.80804;
RA   Ohtsuka H., Ogawa Y., Mizuno H., Mita S., Aiba H.;
RT   "Identification of Ecl family genes that extend chronological lifespan in
RT   fission yeast.";
RL   Biosci. Biotechnol. Biochem. 73:885-889(2009).
CC   -!- FUNCTION: Involved in chronological cell aging.
CC       {ECO:0000269|PubMed:19352039}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:19352039}.
CC   -!- INDUCTION: Up-regulated transiently when the growth phase was changed
CC       from the log phase to the stationary phase.
CC       {ECO:0000269|PubMed:19352039}.
CC   -!- SIMILARITY: Belongs to the ecl1 family. {ECO:0000305}.
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DR   EMBL; CU329671; CBA11508.1; -; Genomic_DNA.
DR   RefSeq; XP_002788940.1; XM_002788894.2.
DR   AlphaFoldDB; C6Y4C5; -.
DR   SMR; C6Y4C5; -.
DR   BioGRID; 1028491; 6.
DR   STRING; 4896.SPBP35G2.16c.1; -.
DR   iPTMnet; C6Y4C5; -.
DR   PaxDb; C6Y4C5; -.
DR   PRIDE; C6Y4C5; -.
DR   EnsemblFungi; SPBP35G2.16c.1; SPBP35G2.16c.1:pep; SPBP35G2.16c.
DR   PomBase; SPBP35G2.16c; ecl2.
DR   VEuPathDB; FungiDB:SPBP35G2.16c; -.
DR   HOGENOM; CLU_2528757_0_0_1; -.
DR   OMA; YCSRECH; -.
DR   PRO; PR:C6Y4C5; -.
DR   Proteomes; UP000002485; Chromosome II.
DR   GO; GO:0005634; C:nucleus; IDA:PomBase.
PE   2: Evidence at transcript level;
KW   Nucleus; Reference proteome.
FT   CHAIN           1..84
FT                   /note="Extender of the chronological lifespan protein 2"
FT                   /id="PRO_0000389115"
SQ   SEQUENCE   84 AA;  9216 MW;  239C2A5545135F83 CRC64;
     MDLDYCIICG KPTTGNLYCS RECHLQDCPG CGSTSEQCSY SKSADLHMLS SQYLDHFRRR
     SSMPSPSTSS SLLNGFVASR LAVL