ID   ECL3_SCHPO              Reviewed;          89 AA.
AC   C6Y4C3;
DT   24-NOV-2009, integrated into UniProtKB/Swiss-Prot.
DT   22-SEP-2009, sequence version 1.
DT   25-MAY-2022, entry version 46.
DE   RecName: Full=Extender of the chronological lifespan protein ecl3;
GN   Name=ecl3; ORFNames=SPBC8E4.12c;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   FUNCTION, AND INDUCTION.
RX   PubMed=19352039; DOI=10.1271/bbb.80804;
RA   Ohtsuka H., Ogawa Y., Mizuno H., Mita S., Aiba H.;
RT   "Identification of Ecl family genes that extend chronological lifespan in
RT   fission yeast.";
RL   Biosci. Biotechnol. Biochem. 73:885-889(2009).
CC   -!- FUNCTION: Involved in chronological cell aging.
CC       {ECO:0000269|PubMed:19352039}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- INDUCTION: Up-regulated transiently when the growth phase was changed
CC       from the log phase to the stationary phase.
CC       {ECO:0000269|PubMed:19352039}.
CC   -!- SIMILARITY: Belongs to the ecl1 family. {ECO:0000305}.
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DR   EMBL; CU329671; CBA11513.1; -; Genomic_DNA.
DR   RefSeq; XP_002788945.1; XM_002788899.1.
DR   AlphaFoldDB; C6Y4C3; -.
DR   BioGRID; 1028582; 6.
DR   STRING; 4896.SPBC8E4.12c.1; -.
DR   PaxDb; C6Y4C3; -.
DR   EnsemblFungi; SPBC8E4.12c.1; SPBC8E4.12c.1:pep; SPBC8E4.12c.
DR   PomBase; SPBC8E4.12c; ecl3.
DR   VEuPathDB; FungiDB:SPBC8E4.12c; -.
DR   HOGENOM; CLU_2456041_0_0_1; -.
DR   OMA; NATTELW; -.
DR   PRO; PR:C6Y4C3; -.
DR   Proteomes; UP000002485; Chromosome II.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
PE   2: Evidence at transcript level;
KW   Nucleus; Reference proteome.
FT   CHAIN           1..89
FT                   /note="Extender of the chronological lifespan protein ecl3"
FT                   /id="PRO_0000389116"
SQ   SEQUENCE   89 AA;  10051 MW;  5FB778A5120CDC04 CRC64;
     MDLNLCLLCG NSIDAEGLYC SNECRIQDKA TTELFSDPLK SPSLNETIDY LALNYFDLFS
     RRSSMCSSSN SSIYSGIYYT ELKNYSVEN