ECM1_SCHPO
ID ECM1_SCHPO Reviewed; 111 AA.
AC Q9UUA0;
DT 11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT 11-JUL-2012, sequence version 2.
DT 03-AUG-2022, entry version 86.
DE RecName: Full=Shuttling pre-60S factor C23B6.02c;
GN ORFNames=SPCC23B6.02c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP REVISION OF GENE MODEL.
RX PubMed=21511999; DOI=10.1126/science.1203357;
RA Rhind N., Chen Z., Yassour M., Thompson D.A., Haas B.J., Habib N.,
RA Wapinski I., Roy S., Lin M.F., Heiman D.I., Young S.K., Furuya K., Guo Y.,
RA Pidoux A., Chen H.M., Robbertse B., Goldberg J.M., Aoki K., Bayne E.H.,
RA Berlin A.M., Desjardins C.A., Dobbs E., Dukaj L., Fan L., FitzGerald M.G.,
RA French C., Gujja S., Hansen K., Keifenheim D., Levin J.Z., Mosher R.A.,
RA Mueller C.A., Pfiffner J., Priest M., Russ C., Smialowska A., Swoboda P.,
RA Sykes S.M., Vaughn M., Vengrova S., Yoder R., Zeng Q., Allshire R.,
RA Baulcombe D., Birren B.W., Brown W., Ekwall K., Kellis M., Leatherwood J.,
RA Levin H., Margalit H., Martienssen R., Nieduszynski C.A., Spatafora J.W.,
RA Friedman N., Dalgaard J.Z., Baumann P., Niki H., Regev A., Nusbaum C.;
RT "Comparative functional genomics of the fission yeasts.";
RL Science 332:930-936(2011).
CC -!- FUNCTION: Pre-ribosomal factor involved in 60S ribosomal protein
CC subunit export from the nucleus. {ECO:0000250}.
CC -!- SUBUNIT: Associates with the pre-60S ribosomal particle and the
CC nucleopore complex. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}. Nucleus
CC {ECO:0000250}. Cytoplasm {ECO:0000250}. Note=Shuttles between the
CC nucleus and the cytoplasm. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the ECM1 family. {ECO:0000305}.
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DR EMBL; CU329672; CAB51561.2; -; Genomic_DNA.
DR PIR; T41242; T41242.
DR RefSeq; NP_588125.2; NM_001023115.2.
DR AlphaFoldDB; Q9UUA0; -.
DR SMR; Q9UUA0; -.
DR BioGRID; 275492; 5.
DR STRING; 4896.SPCC23B6.02c.1; -.
DR iPTMnet; Q9UUA0; -.
DR MaxQB; Q9UUA0; -.
DR PaxDb; Q9UUA0; -.
DR PRIDE; Q9UUA0; -.
DR EnsemblFungi; SPCC23B6.02c.1; SPCC23B6.02c.1:pep; SPCC23B6.02c.
DR GeneID; 2538915; -.
DR KEGG; spo:SPCC23B6.02c; -.
DR PomBase; SPCC23B6.02c; -.
DR VEuPathDB; FungiDB:SPCC23B6.02c; -.
DR HOGENOM; CLU_2159874_0_0_1; -.
DR OMA; RQTKDVN; -.
DR PRO; PR:Q9UUA0; -.
DR Proteomes; UP000002485; Chromosome III.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0016020; C:membrane; NAS:PomBase.
DR GO; GO:0005730; C:nucleolus; ISO:PomBase.
DR GO; GO:0030687; C:preribosome, large subunit precursor; ISO:PomBase.
DR GO; GO:0000055; P:ribosomal large subunit export from nucleus; ISO:PomBase.
DR InterPro; IPR022784; Ribosome_bgen_Alb1.
DR Pfam; PF09135; Alb1; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Nucleus; Reference proteome; Ribosome biogenesis; Transport.
FT CHAIN 1..111
FT /note="Shuttling pre-60S factor C23B6.02c"
FT /id="PRO_0000304032"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 47..111
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 71..111
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 111 AA; 12417 MW; D58641C1D4B5C43D CRC64;
MAKKQSIRSR NFRRSDPAYD LDSSTAIENE TKLSVKEKVA KEIANIALRS GGSESNGISK
KKKNKKQTSK KAKDKLAAAL KAQAREERLD TKISKSLQKQ EKLKARKQGD E
