ID   ECM34_YEAST             Reviewed;         170 AA.
AC   P38728; D3DKS7;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1995, sequence version 1.
DT   03-AUG-2022, entry version 124.
DE   RecName: Full=Protein ECM34;
DE   AltName: Full=Extracellular mutant protein 34;
GN   Name=ECM34; OrderedLocusNames=YHL043W;
OS   Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=559292;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=8091229; DOI=10.1126/science.8091229;
RA   Johnston M., Andrews S., Brinkman R., Cooper J., Ding H., Dover J., Du Z.,
RA   Favello A., Fulton L., Gattung S., Geisel C., Kirsten J., Kucaba T.,
RA   Hillier L.W., Jier M., Johnston L., Langston Y., Latreille P., Louis E.J.,
RA   Macri C., Mardis E., Menezes S., Mouser L., Nhan M., Rifkin L., Riles L.,
RA   St Peter H., Trevaskis E., Vaughan K., Vignati D., Wilcox L., Wohldman P.,
RA   Waterston R., Wilson R., Vaudin M.;
RT   "Complete nucleotide sequence of Saccharomyces cerevisiae chromosome
RT   VIII.";
RL   Science 265:2077-2082(1994).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=24374639; DOI=10.1534/g3.113.008995;
RA   Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA   Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA   Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT   "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL   G3 (Bethesda) 4:389-398(2014).
RN   [3]
RP   IDENTIFICATION.
RX   PubMed=9335584; DOI=10.1093/genetics/147.2.435;
RA   Lussier M., White A.-M., Sheraton J., di Paolo T., Treadwell J.,
RA   Southard S.B., Horenstein C.I., Chen-Weiner J., Ram A.F.J., Kapteyn J.C.,
RA   Roemer T.W., Vo D.H., Bondoc D.C., Hall J., Zhong W.-W., Sdicu A.-M.,
RA   Davies J., Klis F.M., Robbins P.W., Bussey H.;
RT   "Large scale identification of genes involved in cell surface biosynthesis
RT   and architecture in Saccharomyces cerevisiae.";
RL   Genetics 147:435-450(1997).
CC   -!- FUNCTION: May be involved in cell wall organization and biogenesis.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the DUP/COS family. {ECO:0000305}.
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DR   EMBL; U11583; AAB65055.1; -; Genomic_DNA.
DR   EMBL; BK006934; DAA06644.1; -; Genomic_DNA.
DR   PIR; S48925; S48925.
DR   RefSeq; NP_011820.1; NM_001179123.1.
DR   AlphaFoldDB; P38728; -.
DR   BioGRID; 36381; 34.
DR   DIP; DIP-4408N; -.
DR   IntAct; P38728; 1.
DR   STRING; 4932.YHL043W; -.
DR   PaxDb; P38728; -.
DR   EnsemblFungi; YHL043W_mRNA; YHL043W; YHL043W.
DR   GeneID; 856342; -.
DR   KEGG; sce:YHL043W; -.
DR   SGD; S000001035; ECM34.
DR   VEuPathDB; FungiDB:YHL043W; -.
DR   GeneTree; ENSGT00940000176283; -.
DR   HOGENOM; CLU_1548830_0_0_1; -.
DR   OMA; NTEYFFC; -.
DR   BioCyc; YEAST:G3O-31060-MON; -.
DR   PRO; PR:P38728; -.
DR   Proteomes; UP000002311; Chromosome VIII.
DR   RNAct; P38728; protein.
DR   GO; GO:0005829; C:cytosol; HDA:SGD.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0071555; P:cell wall organization; IEA:UniProtKB-KW.
DR   InterPro; IPR001142; DUP/COS.
DR   Pfam; PF00674; DUP; 1.
PE   3: Inferred from homology;
KW   Cell wall biogenesis/degradation; Glycoprotein; Membrane;
KW   Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..170
FT                   /note="Protein ECM34"
FT                   /id="PRO_0000207532"
FT   TRANSMEM        51..71
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        98..118
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        45
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   170 AA;  19812 MW;  236F6CBF54488ED5 CRC64;
     MEGRKSEDEK NEAALACDVF ESSNAKLPKN VFRSSFTWYC YEVINRSAFH IWLLLCLTLI
     VGWKVFSGIG GRRPSDSNMD GPQTKHKRNP GFLRRHSTIV ILVISLAVSF SWEAFKMYRE
     RTFGKQITQF AKEIIKSAPS TDMESWDRVA ADFNSYMYEN KLWNTEYFFC