ID   ECM8_YEAST              Reviewed;         354 AA.
AC   P38246; D6VQ75;
DT   01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT   27-JUL-2011, sequence version 2.
DT   03-AUG-2022, entry version 134.
DE   RecName: Full=Protein ECM8;
DE   AltName: Full=Extracellular mutant protein 8;
GN   Name=ECM8; OrderedLocusNames=YBR076W; ORFNames=YBR0722;
OS   Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=559292;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=7985423; DOI=10.1002/yea.320100711;
RA   van der Aart Q.J.M., Barthe C., Doignon F., Aigle M., Crouzet M.,
RA   Steensma H.Y.;
RT   "Sequence analysis of a 31 kb DNA fragment from the right arm of
RT   Saccharomyces cerevisiae chromosome II.";
RL   Yeast 10:959-964(1994).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=7813418; DOI=10.1002/j.1460-2075.1994.tb06923.x;
RA   Feldmann H., Aigle M., Aljinovic G., Andre B., Baclet M.C., Barthe C.,
RA   Baur A., Becam A.-M., Biteau N., Boles E., Brandt T., Brendel M.,
RA   Brueckner M., Bussereau F., Christiansen C., Contreras R., Crouzet M.,
RA   Cziepluch C., Demolis N., Delaveau T., Doignon F., Domdey H.,
RA   Duesterhus S., Dubois E., Dujon B., El Bakkoury M., Entian K.-D.,
RA   Feuermann M., Fiers W., Fobo G.M., Fritz C., Gassenhuber J., Glansdorff N.,
RA   Goffeau A., Grivell L.A., de Haan M., Hein C., Herbert C.J.,
RA   Hollenberg C.P., Holmstroem K., Jacq C., Jacquet M., Jauniaux J.-C.,
RA   Jonniaux J.-L., Kallesoee T., Kiesau P., Kirchrath L., Koetter P.,
RA   Korol S., Liebl S., Logghe M., Lohan A.J.E., Louis E.J., Li Z.Y.,
RA   Maat M.J., Mallet L., Mannhaupt G., Messenguy F., Miosga T., Molemans F.,
RA   Mueller S., Nasr F., Obermaier B., Perea J., Pierard A., Piravandi E.,
RA   Pohl F.M., Pohl T.M., Potier S., Proft M., Purnelle B., Ramezani Rad M.,
RA   Rieger M., Rose M., Schaaff-Gerstenschlaeger I., Scherens B.,
RA   Schwarzlose C., Skala J., Slonimski P.P., Smits P.H.M., Souciet J.-L.,
RA   Steensma H.Y., Stucka R., Urrestarazu L.A., van der Aart Q.J.M.,
RA   Van Dyck L., Vassarotti A., Vetter I., Vierendeels F., Vissers S.,
RA   Wagner G., de Wergifosse P., Wolfe K.H., Zagulski M., Zimmermann F.K.,
RA   Mewes H.-W., Kleine K.;
RT   "Complete DNA sequence of yeast chromosome II.";
RL   EMBO J. 13:5795-5809(1994).
RN   [3]
RP   GENOME REANNOTATION, AND SEQUENCE REVISION TO 74 AND 353.
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=24374639; DOI=10.1534/g3.113.008995;
RA   Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA   Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA   Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT   "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL   G3 (Bethesda) 4:389-398(2014).
RN   [4]
RP   IDENTIFICATION.
RX   PubMed=9335584; DOI=10.1093/genetics/147.2.435;
RA   Lussier M., White A.-M., Sheraton J., di Paolo T., Treadwell J.,
RA   Southard S.B., Horenstein C.I., Chen-Weiner J., Ram A.F.J., Kapteyn J.C.,
RA   Roemer T.W., Vo D.H., Bondoc D.C., Hall J., Zhong W.-W., Sdicu A.-M.,
RA   Davies J., Klis F.M., Robbins P.W., Bussey H.;
RT   "Large scale identification of genes involved in cell surface biosynthesis
RT   and architecture in Saccharomyces cerevisiae.";
RL   Genetics 147:435-450(1997).
CC   -!- FUNCTION: May be involved in cell wall organization and biogenesis.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAA53933.1; Type=Frameshift; Evidence={ECO:0000305};
CC       Sequence=CAA85020.1; Type=Frameshift; Evidence={ECO:0000305};
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DR   EMBL; X76294; CAA53933.1; ALT_FRAME; Genomic_DNA.
DR   EMBL; Z35945; CAA85020.1; ALT_FRAME; Genomic_DNA.
DR   EMBL; BK006936; DAA07195.2; -; Genomic_DNA.
DR   PIR; S45471; S45471.
DR   RefSeq; NP_009632.2; NM_001178424.2.
DR   AlphaFoldDB; P38246; -.
DR   BioGRID; 32778; 197.
DR   DIP; DIP-5145N; -.
DR   STRING; 4932.YBR076W; -.
DR   PaxDb; P38246; -.
DR   EnsemblFungi; YBR076W_mRNA; YBR076W; YBR076W.
DR   GeneID; 852368; -.
DR   KEGG; sce:YBR076W; -.
DR   SGD; S000000280; ECM8.
DR   VEuPathDB; FungiDB:YBR076W; -.
DR   eggNOG; ENOG502RXYS; Eukaryota.
DR   HOGENOM; CLU_055691_0_0_1; -.
DR   InParanoid; P38246; -.
DR   OMA; HCENWIR; -.
DR   BioCyc; YEAST:G3O-29044-MON; -.
DR   PRO; PR:P38246; -.
DR   Proteomes; UP000002311; Chromosome II.
DR   RNAct; P38246; protein.
DR   GO; GO:0071555; P:cell wall organization; IEA:UniProtKB-KW.
DR   InterPro; IPR028012; Rua1_C.
DR   Pfam; PF14616; DUF4451; 1.
PE   4: Predicted;
KW   Cell wall biogenesis/degradation; Reference proteome.
FT   CHAIN           1..354
FT                   /note="Protein ECM8"
FT                   /id="PRO_0000086924"
SQ   SEQUENCE   354 AA;  41770 MW;  3B3326E84C502C2D CRC64;
     MDYGYFFPAQ RIEETNGVDF WIDSNAEFTQ SKRPDSSTST LSRVLTDTTN VSNNSGSLKR
     KTIKNKIFPQ RKIFNDSENF DFGKANTDCK HVFKSISKQL IFLPRCFQHH SIRGWMKDRY
     SEFGYKIKRN QNCPPSACVQ ALYNTSRSNT EESNPNSLDS LIMYKYMRYS EKKKELMCRF
     CQGNNWILAE NYLKHLFFAH GILSEFKPHT LYHFESKLLK IQGKLNFKIQ VLKEPEFSKK
     ILNSLTVSII PSPLAYYTQT LNGGFRRIHV KCPHCENWIR LGWCEYDEII RDSFQDFESL
     RNLNADYNGM SYIQTRNRED IEGIYENYFT HYIQCDLATF RTKCLYVQVI TKSN