ID   ECNB_ECO57              Reviewed;          48 AA.
AC   P0ADB9; P56549;
DT   06-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   06-DEC-2005, sequence version 1.
DT   25-MAY-2022, entry version 78.
DE   RecName: Full=Entericidin B;
DE   Flags: Precursor;
GN   Name=ecnB; OrderedLocusNames=Z5754, ECs5128.2;
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J.,
RA   Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G.,
RA   Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J.,
RA   Davis N.W., Lim A., Dimalanta E.T., Potamousis K., Apodaca J.,
RA   Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A.,
RA   Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T.,
RA   Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T., Kuhara S.,
RA   Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and
RT   genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
CC   -!- FUNCTION: Plays a role in the bacteriolysis. Is activated under
CC       conditions of high osmolarity by the factor sigma S. Entericidin A
CC       functions as an antidote (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|PROSITE-
CC       ProRule:PRU00303}; Lipid-anchor {ECO:0000255|PROSITE-ProRule:PRU00303}.
CC   -!- SIMILARITY: Belongs to the EcnA/EcnB lipoprotein family. {ECO:0000305}.
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DR   EMBL; AE005174; AAG59348.1; -; Genomic_DNA.
DR   EMBL; BA000007; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   PIR; H86110; H86110.
DR   RefSeq; WP_000239596.1; NZ_SWKA01000005.1.
DR   AlphaFoldDB; P0ADB9; -.
DR   STRING; 155864.EDL933_5497; -.
DR   EnsemblBacteria; AAG59348; AAG59348; Z5754.
DR   GeneID; 67414767; -.
DR   KEGG; ece:Z5754; -.
DR   PATRIC; fig|83334.175.peg.5688; -.
DR   eggNOG; COG5510; Bacteria.
DR   Proteomes; UP000000558; Chromosome.
DR   Proteomes; UP000002519; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0009636; P:response to toxic substance; IEA:InterPro.
DR   InterPro; IPR012556; Entericidin.
DR   Pfam; PF08085; Entericidin; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Lipoprotein; Membrane; Palmitate; Reference proteome;
KW   Signal.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   PEPTIDE         22..48
FT                   /note="Entericidin B"
FT                   /id="PRO_0000043192"
FT   LIPID           22
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000305"
FT   LIPID           22
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   48 AA;  4810 MW;  9814A908CA6A70CC CRC64;
     MVKKTIAAIF SVLVLSTVLT ACNTTRGVGE DISDGGNAIS GAATKAQQ