ID   ECOT2_LEIBR             Reviewed;         154 AA.
AC   A4H823;
DT   26-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2007, sequence version 1.
DT   25-MAY-2022, entry version 62.
DE   RecName: Full=Ecotin-like protein 2;
GN   ORFNames=LbrM15_V2.0540, LbrM_15_0540;
OS   Leishmania braziliensis.
OC   Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC   Trypanosomatida; Trypanosomatidae; Leishmaniinae; Leishmania;
OC   Leishmania braziliensis species complex.
OX   NCBI_TaxID=5660;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MHOM/BR/75/M2904;
RX   PubMed=17572675; DOI=10.1038/ng2053;
RA   Peacock C.S., Seeger K., Harris D., Murphy L., Ruiz J.C., Quail M.A.,
RA   Peters N., Adlem E., Tivey A., Aslett M., Kerhornou A., Ivens A.,
RA   Fraser A., Rajandream M.-A., Carver T., Norbertczak H., Chillingworth T.,
RA   Hance Z., Jagels K., Moule S., Ormond D., Rutter S., Sqaures R.,
RA   Whitehead S., Rabbinowitsch E., Arrowsmith C., White B., Thurston S.,
RA   Bringaud F., Baldauf S.L., Faulconbridge A., Jeffares D., Depledge D.P.,
RA   Oyola S.O., Hilley J.D., Brito L.O., Tosi L.R.O., Barrell B., Cruz A.K.,
RA   Mottram J.C., Smith D.F., Berriman M.;
RT   "Comparative genomic analysis of three Leishmania species that cause
RT   diverse human disease.";
RL   Nat. Genet. 39:839-847(2007).
CC   -!- SIMILARITY: Belongs to the protease inhibitor I11 (ecotin) family.
CC       {ECO:0000305}.
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DR   EMBL; FR798989; CAM42071.1; -; Genomic_DNA.
DR   RefSeq; XP_001563502.1; XM_001563452.1.
DR   AlphaFoldDB; A4H823; -.
DR   SMR; A4H823; -.
DR   STRING; 5660.A4H823; -.
DR   GeneID; 5414020; -.
DR   KEGG; lbz:LBRM_15_0540; -.
DR   VEuPathDB; TriTrypDB:LbrM.15.0540; -.
DR   VEuPathDB; TriTrypDB:LBRM2903_150011200; -.
DR   InParanoid; A4H823; -.
DR   OMA; PKAEKGM; -.
DR   Proteomes; UP000007258; Chromosome 15.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:InterPro.
DR   Gene3D; 4.10.1230.10; -; 1.
DR   InterPro; IPR027438; Ecotin_C.
DR   InterPro; IPR036198; Ecotin_sf.
DR   InterPro; IPR005658; Prot_inh_ecotin.
DR   PANTHER; PTHR35890; PTHR35890; 1.
DR   Pfam; PF03974; Ecotin; 1.
DR   SUPFAM; SSF49772; SSF49772; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..154
FT                   /note="Ecotin-like protein 2"
FT                   /id="PRO_0000291593"
SQ   SEQUENCE   154 AA;  17246 MW;  296DDD040D5D86F6 CRC64;
     MSAAAGKTLA DYKAPYPKPT SRQRRYVILL DPKGDNAELN DYKVELIPGR VKLLDGANHY
     FLGGKIEEKT IDGWGYPYYV VTLAEMAGTA MLPLGNAAHK KLRFVPLHTS SLYRYNSKLP
     IVVYVPKDGV LRYRIWTAKL SGRGKAKSIK AKEM