ID   ECOT2_LEIIN             Reviewed;         158 AA.
AC   A4HWE9;
DT   26-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2007, sequence version 1.
DT   25-MAY-2022, entry version 61.
DE   RecName: Full=Ecotin-like protein 2;
GN   ORFNames=LinJ15.0530, LinJ_15_0530;
OS   Leishmania infantum.
OC   Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC   Trypanosomatida; Trypanosomatidae; Leishmaniinae; Leishmania.
OX   NCBI_TaxID=5671;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JPCM5;
RX   PubMed=17572675; DOI=10.1038/ng2053;
RA   Peacock C.S., Seeger K., Harris D., Murphy L., Ruiz J.C., Quail M.A.,
RA   Peters N., Adlem E., Tivey A., Aslett M., Kerhornou A., Ivens A.,
RA   Fraser A., Rajandream M.-A., Carver T., Norbertczak H., Chillingworth T.,
RA   Hance Z., Jagels K., Moule S., Ormond D., Rutter S., Sqaures R.,
RA   Whitehead S., Rabbinowitsch E., Arrowsmith C., White B., Thurston S.,
RA   Bringaud F., Baldauf S.L., Faulconbridge A., Jeffares D., Depledge D.P.,
RA   Oyola S.O., Hilley J.D., Brito L.O., Tosi L.R.O., Barrell B., Cruz A.K.,
RA   Mottram J.C., Smith D.F., Berriman M.;
RT   "Comparative genomic analysis of three Leishmania species that cause
RT   diverse human disease.";
RL   Nat. Genet. 39:839-847(2007).
CC   -!- SIMILARITY: Belongs to the protease inhibitor I11 (ecotin) family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; FR796447; CAM66774.1; -; Genomic_DNA.
DR   RefSeq; XP_001464390.1; XM_001464353.1.
DR   AlphaFoldDB; A4HWE9; -.
DR   SMR; A4HWE9; -.
DR   STRING; 5671.XP_001464390.1; -.
DR   GeneID; 5067780; -.
DR   KEGG; lif:LINJ_15_0530; -.
DR   VEuPathDB; TriTrypDB:LINF_150012400; -.
DR   eggNOG; ENOG502S3WU; Eukaryota.
DR   InParanoid; A4HWE9; -.
DR   OMA; PKAEKGM; -.
DR   Proteomes; UP000008153; Chromosome 15.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:InterPro.
DR   Gene3D; 4.10.1230.10; -; 1.
DR   InterPro; IPR027438; Ecotin_C.
DR   InterPro; IPR036198; Ecotin_sf.
DR   InterPro; IPR005658; Prot_inh_ecotin.
DR   PANTHER; PTHR35890; PTHR35890; 1.
DR   Pfam; PF03974; Ecotin; 1.
DR   SUPFAM; SSF49772; SSF49772; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..158
FT                   /note="Ecotin-like protein 2"
FT                   /id="PRO_0000291594"
SQ   SEQUENCE   158 AA;  17736 MW;  EF6A082644E64532 CRC64;
     MPAGMSGAAG KTLANFKAPY PEPTSQQRRY VIFLDPKGYR KELNDYKVEL IPGRVEKVDG
     ANVYRMGGSI EERTIDGWGY TYYVVTLTTM SGTLMMPLGD AALKRPRFVA MSTNNLYRYN
     SQLPIVVYTP KDGELRYRIW TVKSTGSGTA KSINAREM