ID   ECOT2_TRYCC             Reviewed;         147 AA.
AC   Q4D4Y5;
DT   26-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT   13-SEP-2005, sequence version 1.
DT   25-MAY-2022, entry version 51.
DE   RecName: Full=Ecotin-like protein 2;
GN   ORFNames=Tc00.1047053508533.40;
OS   Trypanosoma cruzi (strain CL Brener).
OC   Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC   Trypanosomatida; Trypanosomatidae; Trypanosoma; Schizotrypanum.
OX   NCBI_TaxID=353153;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CL Brener;
RX   PubMed=16020725; DOI=10.1126/science.1112631;
RA   El-Sayed N.M.A., Myler P.J., Bartholomeu D.C., Nilsson D., Aggarwal G.,
RA   Tran A.-N., Ghedin E., Worthey E.A., Delcher A.L., Blandin G.,
RA   Westenberger S.J., Caler E., Cerqueira G.C., Branche C., Haas B.,
RA   Anupama A., Arner E., Aslund L., Attipoe P., Bontempi E., Bringaud F.,
RA   Burton P., Cadag E., Campbell D.A., Carrington M., Crabtree J., Darban H.,
RA   da Silveira J.F., de Jong P., Edwards K., Englund P.T., Fazelina G.,
RA   Feldblyum T., Ferella M., Frasch A.C., Gull K., Horn D., Hou L., Huang Y.,
RA   Kindlund E., Klingbeil M., Kluge S., Koo H., Lacerda D., Levin M.J.,
RA   Lorenzi H., Louie T., Machado C.R., McCulloch R., McKenna A., Mizuno Y.,
RA   Mottram J.C., Nelson S., Ochaya S., Osoegawa K., Pai G., Parsons M.,
RA   Pentony M., Pettersson U., Pop M., Ramirez J.L., Rinta J., Robertson L.,
RA   Salzberg S.L., Sanchez D.O., Seyler A., Sharma R., Shetty J., Simpson A.J.,
RA   Sisk E., Tammi M.T., Tarleton R., Teixeira S., Van Aken S., Vogt C.,
RA   Ward P.N., Wickstead B., Wortman J., White O., Fraser C.M., Stuart K.D.,
RA   Andersson B.;
RT   "The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas
RT   disease.";
RL   Science 309:409-415(2005).
CC   -!- SIMILARITY: Belongs to the protease inhibitor I11 (ecotin) family.
CC       {ECO:0000305}.
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DR   EMBL; AAHK01001013; EAN87589.1; -; Genomic_DNA.
DR   RefSeq; XP_809440.1; XM_804347.1.
DR   AlphaFoldDB; Q4D4Y5; -.
DR   SMR; Q4D4Y5; -.
DR   STRING; 5693.XP_809440.1; -.
DR   PaxDb; Q4D4Y5; -.
DR   EnsemblProtists; EAN87589; EAN87589; Tc00.1047053508533.40.
DR   GeneID; 3540047; -.
DR   KEGG; tcr:508533.40; -.
DR   eggNOG; ENOG502S3WU; Eukaryota.
DR   OMA; PKAEKGM; -.
DR   OrthoDB; 1512958at2759; -.
DR   Proteomes; UP000002296; Unassembled WGS sequence.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:InterPro.
DR   InterPro; IPR036198; Ecotin_sf.
DR   InterPro; IPR005658; Prot_inh_ecotin.
DR   PANTHER; PTHR35890; PTHR35890; 1.
DR   Pfam; PF03974; Ecotin; 1.
DR   PIRSF; PIRSF006865; Prot_inh_ecotin; 1.
DR   SUPFAM; SSF49772; SSF49772; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..147
FT                   /note="Ecotin-like protein 2"
FT                   /id="PRO_0000291596"
SQ   SEQUENCE   147 AA;  16821 MW;  CA449FEBD8E465C1 CRC64;
     MSTAPKTLAD YQAPYPEATP NQKRYVIFLE EKDYDSELEE YKLQLIPGRV MKVDPVNRCF
     IAGSVKEKTI PGWGYNYYVV EMGPMATTLM AVSPGSPPVR KFVPMAERPF IPYNSKLPVV
     VYMPKEGELH YRVWTPTKPK EEIAGER