ID   ECOT4_TRYB2             Reviewed;         165 AA.
AC   Q57ZP2;
DT   26-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT   10-MAY-2005, sequence version 1.
DT   03-AUG-2022, entry version 65.
DE   RecName: Full=Ecotin-like protein 4;
GN   ORFNames=Tb927.5.1730;
OS   Trypanosoma brucei brucei (strain 927/4 GUTat10.1).
OC   Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC   Trypanosomatida; Trypanosomatidae; Trypanosoma.
OX   NCBI_TaxID=185431;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=927/4 GUTat10.1 {ECO:0000312|Proteomes:UP000008524};
RX   PubMed=16020726; DOI=10.1126/science.1112642;
RA   Berriman M., Ghedin E., Hertz-Fowler C., Blandin G., Renauld H.,
RA   Bartholomeu D.C., Lennard N.J., Caler E., Hamlin N.E., Haas B., Bohme U.,
RA   Hannick L., Aslett M.A., Shallom J., Marcello L., Hou L., Wickstead B.,
RA   Alsmark U.C.M., Arrowsmith C., Atkin R.J., Barron A.J., Bringaud F.,
RA   Brooks K., Carrington M., Cherevach I., Chillingworth T.J., Churcher C.,
RA   Clark L.N., Corton C.H., Cronin A., Davies R.M., Doggett J., Djikeng A.,
RA   Feldblyum T., Field M.C., Fraser A., Goodhead I., Hance Z., Harper D.,
RA   Harris B.R., Hauser H., Hostetler J., Ivens A., Jagels K., Johnson D.,
RA   Johnson J., Jones K., Kerhornou A.X., Koo H., Larke N., Landfear S.,
RA   Larkin C., Leech V., Line A., Lord A., Macleod A., Mooney P.J., Moule S.,
RA   Martin D.M., Morgan G.W., Mungall K., Norbertczak H., Ormond D., Pai G.,
RA   Peacock C.S., Peterson J., Quail M.A., Rabbinowitsch E., Rajandream M.A.,
RA   Reitter C., Salzberg S.L., Sanders M., Schobel S., Sharp S., Simmonds M.,
RA   Simpson A.J., Tallon L., Turner C.M., Tait A., Tivey A.R., Van Aken S.,
RA   Walker D., Wanless D., Wang S., White B., White O., Whitehead S.,
RA   Woodward J., Wortman J., Adams M.D., Embley T.M., Gull K., Ullu E.,
RA   Barry J.D., Fairlamb A.H., Opperdoes F., Barrell B.G., Donelson J.E.,
RA   Hall N., Fraser C.M., Melville S.E., El-Sayed N.M.A.;
RT   "The genome of the African trypanosome Trypanosoma brucei.";
RL   Science 309:416-422(2005).
CC   -!- SIMILARITY: Belongs to the protease inhibitor I11 (ecotin) family.
CC       {ECO:0000305}.
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DR   EMBL; AC104617; AAX79124.1; -; Genomic_DNA.
DR   RefSeq; XP_844847.1; XM_839754.1.
DR   AlphaFoldDB; Q57ZP2; -.
DR   SMR; Q57ZP2; -.
DR   PaxDb; Q57ZP2; -.
DR   PRIDE; Q57ZP2; -.
DR   GeneID; 3657286; -.
DR   KEGG; tbr:Tb927.5.1730; -.
DR   VEuPathDB; TriTrypDB:Tb927.5.1730; -.
DR   OMA; NDAANHQ; -.
DR   Proteomes; UP000008524; Chromosome 5.
DR   GO; GO:0120119; C:flagellum attachment zone; IDA:GeneDB.
DR   GO; GO:0097740; C:paraflagellar rod; IDA:GeneDB.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:InterPro.
DR   InterPro; IPR036198; Ecotin_sf.
DR   InterPro; IPR005658; Prot_inh_ecotin.
DR   PANTHER; PTHR35890; PTHR35890; 1.
DR   Pfam; PF03974; Ecotin; 1.
DR   PIRSF; PIRSF006865; Prot_inh_ecotin; 1.
DR   SUPFAM; SSF49772; SSF49772; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..165
FT                   /note="Ecotin-like protein 4"
FT                   /id="PRO_0000291610"
SQ   SEQUENCE   165 AA;  19342 MW;  EE06716BEE515476 CRC64;
     MFGSRKASRR RSYRSRSTMG SRVDIDFCKF EEPPSPREGE RRCLFVLDPL EHYVESKDRM
     VELLPGRVET VDGVNTYYIN GCTTEEKFPG LDYTCYRVDL RDTYRSRCAV PPEATPEEKF
     ISHRHRKLIP YNSRKPVVVY LPEDAQLHYR IWTGGQEVVA KKAEE