ID   ECPB_ECO55              Reviewed;         222 AA.
AC   B7L423;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   10-FEB-2009, sequence version 1.
DT   25-MAY-2022, entry version 54.
DE   RecName: Full=Probable fimbrial chaperone EcpB;
DE   Flags: Precursor;
GN   Name=ecpB; Synonyms=matC; OrderedLocusNames=EC55989_0296;
OS   Escherichia coli (strain 55989 / EAEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=585055;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=55989 / EAEC;
RX   PubMed=19165319; DOI=10.1371/journal.pgen.1000344;
RA   Touchon M., Hoede C., Tenaillon O., Barbe V., Baeriswyl S., Bidet P.,
RA   Bingen E., Bonacorsi S., Bouchier C., Bouvet O., Calteau A., Chiapello H.,
RA   Clermont O., Cruveiller S., Danchin A., Diard M., Dossat C., Karoui M.E.,
RA   Frapy E., Garry L., Ghigo J.M., Gilles A.M., Johnson J., Le Bouguenec C.,
RA   Lescat M., Mangenot S., Martinez-Jehanne V., Matic I., Nassif X., Oztas S.,
RA   Petit M.A., Pichon C., Rouy Z., Ruf C.S., Schneider D., Tourret J.,
RA   Vacherie B., Vallenet D., Medigue C., Rocha E.P.C., Denamur E.;
RT   "Organised genome dynamics in the Escherichia coli species results in
RT   highly diverse adaptive paths.";
RL   PLoS Genet. 5:E1000344-E1000344(2009).
CC   -!- FUNCTION: Part of the ecpRABCDE operon, which encodes the E.coli common
CC       pilus (ECP). ECP is found in both commensal and pathogenic strains and
CC       plays a dual role in early-stage biofilm development and host cell
CC       recognition (By similarity). {ECO:0000250}.
CC   -!- INDUCTION: Negatively regulated by H-NS. Positively regulated by IHF
CC       and EcpR (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the EcpB/EcpE family. {ECO:0000305}.
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DR   EMBL; CU928145; CAU96174.1; -; Genomic_DNA.
DR   RefSeq; WP_000716398.1; NC_011748.1.
DR   AlphaFoldDB; B7L423; -.
DR   SMR; B7L423; -.
DR   EnsemblBacteria; CAU96174; CAU96174; EC55989_0296.
DR   GeneID; 66671413; -.
DR   KEGG; eck:EC55989_0296; -.
DR   HOGENOM; CLU_106652_0_0_6; -.
DR   OMA; KENYFVM; -.
DR   Proteomes; UP000000746; Chromosome.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR040695; EcpB_C.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR008962; PapD-like_sf.
DR   Pfam; PF18649; EcpB_C; 1.
DR   SUPFAM; SSF49354; SSF49354; 1.
PE   3: Inferred from homology;
KW   Chaperone; Fimbrium biogenesis; Signal.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000255"
FT   CHAIN           21..222
FT                   /note="Probable fimbrial chaperone EcpB"
FT                   /id="PRO_0000369155"
SQ   SEQUENCE   222 AA;  24517 MW;  2B47AE6230FCC8D1 CRC64;
     MKKHLLPLAL LFSGISPAQA LDVGDISSFM NSDSSTLSKT IKNSTDSGRL INIRLERLSS
     PLDDGQVISM DKPDELLLTP ASLLLPAQAS EVIRFFYKGP ADEKERYYRI VWFDQALSDA
     QRDNANRSAV ATASARIGTI LVVAPRQANY HFQYANGSLT NTGNATLRIL AYGPCLKAAN
     GKECKENYYL MPGKSRRFTR VDTADNKGRV ALWQGDKFIP VK