ID   ECPB_ECO5E              Reviewed;         222 AA.
AC   B5Z1N1;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   25-NOV-2008, sequence version 1.
DT   25-MAY-2022, entry version 51.
DE   RecName: Full=Probable fimbrial chaperone EcpB;
DE   Flags: Precursor;
GN   Name=ecpB; Synonyms=matC; OrderedLocusNames=ECH74115_0338;
OS   Escherichia coli O157:H7 (strain EC4115 / EHEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=444450;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=EC4115 / EHEC;
RX   PubMed=22135463; DOI=10.1073/pnas.1107176108;
RA   Eppinger M., Mammel M.K., Leclerc J.E., Ravel J., Cebula T.A.;
RT   "Genomic anatomy of Escherichia coli O157:H7 outbreaks.";
RL   Proc. Natl. Acad. Sci. U.S.A. 108:20142-20147(2011).
CC   -!- FUNCTION: Part of the ecpRABCDE operon, which encodes the E.coli common
CC       pilus (ECP). ECP is found in both commensal and pathogenic strains and
CC       plays a dual role in early-stage biofilm development and host cell
CC       recognition (By similarity). {ECO:0000250}.
CC   -!- INDUCTION: Negatively regulated by H-NS. Positively regulated by IHF
CC       and EcpR (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the EcpB/EcpE family. {ECO:0000305}.
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DR   EMBL; CP001164; ACI39707.1; -; Genomic_DNA.
DR   RefSeq; WP_000716386.1; NC_011353.1.
DR   AlphaFoldDB; B5Z1N1; -.
DR   SMR; B5Z1N1; -.
DR   KEGG; ecf:ECH74115_0338; -.
DR   HOGENOM; CLU_106652_0_0_6; -.
DR   OMA; KENYFVM; -.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR040695; EcpB_C.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR008962; PapD-like_sf.
DR   Pfam; PF18649; EcpB_C; 1.
DR   SUPFAM; SSF49354; SSF49354; 1.
PE   3: Inferred from homology;
KW   Chaperone; Fimbrium biogenesis; Signal.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000255"
FT   CHAIN           21..222
FT                   /note="Probable fimbrial chaperone EcpB"
FT                   /id="PRO_0000369162"
SQ   SEQUENCE   222 AA;  24513 MW;  C856108D49022473 CRC64;
     MKKHLLLLAL LLSGISPAQA LDVGDISSFM NSDSSTLSKT IKNSTDSGRL INIRLERLSS
     PLDDGQVISM DKPDELLLTP ASLLLPAQAS EVIRFFYKGP ADEKERYYRI VWFDQALSDA
     QRDNANRSAV ATASARIGTI LVVAPRQANY HFQYANGTLT NTGNATLRIL AYGPCLKAAN
     GKECKENYYL MPGKSRRFTR VDTADNKGRV ALWQGDKFIP VK