ID   ECPB_ECOK1              Reviewed;         222 AA.
AC   A1A7X5;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   14-APR-2009, sequence version 2.
DT   25-MAY-2022, entry version 61.
DE   RecName: Full=Probable fimbrial chaperone EcpB;
DE   Flags: Precursor;
GN   Name=ecpB; Synonyms=matC; OrderedLocusNames=Ecok1_02710;
GN   ORFNames=APECO1_1705;
OS   Escherichia coli O1:K1 / APEC.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=405955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=17293413; DOI=10.1128/jb.01726-06;
RA   Johnson T.J., Kariyawasam S., Wannemuehler Y., Mangiamele P., Johnson S.J.,
RA   Doetkott C., Skyberg J.A., Lynne A.M., Johnson J.R., Nolan L.K.;
RT   "The genome sequence of avian pathogenic Escherichia coli strain O1:K1:H7
RT   shares strong similarities with human extraintestinal pathogenic E. coli
RT   genomes.";
RL   J. Bacteriol. 189:3228-3236(2007).
CC   -!- FUNCTION: Part of the ecpRABCDE operon, which encodes the E.coli common
CC       pilus (ECP). ECP is found in both commensal and pathogenic strains and
CC       plays a dual role in early-stage biofilm development and host cell
CC       recognition (By similarity). {ECO:0000250}.
CC   -!- INDUCTION: Negatively regulated by H-NS. Positively regulated by IHF
CC       and EcpR (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the EcpB/EcpE family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=ABI99764.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; CP000468; ABI99764.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_000716404.1; NC_008563.1.
DR   AlphaFoldDB; A1A7X5; -.
DR   SMR; A1A7X5; -.
DR   EnsemblBacteria; ABI99764; ABI99764; APECO1_1705.
DR   KEGG; ecv:APECO1_1705; -.
DR   HOGENOM; CLU_106652_0_0_6; -.
DR   Proteomes; UP000008216; Chromosome.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR040695; EcpB_C.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR008962; PapD-like_sf.
DR   Pfam; PF18649; EcpB_C; 1.
DR   SUPFAM; SSF49354; SSF49354; 1.
PE   3: Inferred from homology;
KW   Chaperone; Fimbrium biogenesis; Signal.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000255"
FT   CHAIN           21..222
FT                   /note="Probable fimbrial chaperone EcpB"
FT                   /id="PRO_0000369163"
SQ   SEQUENCE   222 AA;  24501 MW;  F32908C77A181872 CRC64;
     MKKHLLPLAL LFSGISPAQA LDVGDISSFM NSDSSTLSKT IQNSTDSGRL INIRLERLSS
     PLDDGQVIAM DKPDELLLTP ASLLLPAQAS EVIRFFYKGP ADEKERYYRI VWFDQALSDA
     QRDNANRSAV ATASARIGTI LVVAPRQANY HFQYANGSLT NTGNATLRIL AYGPCLKAAN
     GKECKENYYL MPGKSRRFTR VDTADNKGRV ALWQGDKFIP VK