ID   ECPB_ECOL5              Reviewed;         222 AA.
AC   Q0TKZ2;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   14-APR-2009, sequence version 2.
DT   25-MAY-2022, entry version 70.
DE   RecName: Full=Probable fimbrial chaperone EcpB;
DE   Flags: Precursor;
GN   Name=ecpB; Synonyms=matC; OrderedLocusNames=ECP_0355;
OS   Escherichia coli O6:K15:H31 (strain 536 / UPEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=362663;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=536 / UPEC;
RX   PubMed=16879640; DOI=10.1111/j.1365-2958.2006.05255.x;
RA   Hochhut B., Wilde C., Balling G., Middendorf B., Dobrindt U.,
RA   Brzuszkiewicz E., Gottschalk G., Carniel E., Hacker J.;
RT   "Role of pathogenicity island-associated integrases in the genome
RT   plasticity of uropathogenic Escherichia coli strain 536.";
RL   Mol. Microbiol. 61:584-595(2006).
CC   -!- FUNCTION: Part of the ecpRABCDE operon, which encodes the E.coli common
CC       pilus (ECP). ECP is found in both commensal and pathogenic strains and
CC       plays a dual role in early-stage biofilm development and host cell
CC       recognition (By similarity). {ECO:0000250}.
CC   -!- INDUCTION: Negatively regulated by H-NS. Positively regulated by IHF
CC       and EcpR (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the EcpB/EcpE family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=ABG68389.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; CP000247; ABG68389.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_000716404.1; NC_008253.1.
DR   AlphaFoldDB; Q0TKZ2; -.
DR   SMR; Q0TKZ2; -.
DR   STRING; 362663.ECP_0355; -.
DR   EnsemblBacteria; ABG68389; ABG68389; ECP_0355.
DR   KEGG; ecp:ECP_0355; -.
DR   HOGENOM; CLU_106652_0_0_6; -.
DR   OMA; KENYFVM; -.
DR   Proteomes; UP000009182; Chromosome.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR040695; EcpB_C.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR008962; PapD-like_sf.
DR   Pfam; PF18649; EcpB_C; 1.
DR   SUPFAM; SSF49354; SSF49354; 1.
PE   3: Inferred from homology;
KW   Chaperone; Fimbrium biogenesis; Signal.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000255"
FT   CHAIN           21..222
FT                   /note="Probable fimbrial chaperone EcpB"
FT                   /id="PRO_0000369166"
SQ   SEQUENCE   222 AA;  24501 MW;  F32908C77A181872 CRC64;
     MKKHLLPLAL LFSGISPAQA LDVGDISSFM NSDSSTLSKT IQNSTDSGRL INIRLERLSS
     PLDDGQVIAM DKPDELLLTP ASLLLPAQAS EVIRFFYKGP ADEKERYYRI VWFDQALSDA
     QRDNANRSAV ATASARIGTI LVVAPRQANY HFQYANGSLT NTGNATLRIL AYGPCLKAAN
     GKECKENYYL MPGKSRRFTR VDTADNKGRV ALWQGDKFIP VK