ID   ECPB_ECOUT              Reviewed;         222 AA.
AC   Q1RFQ5;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   14-APR-2009, sequence version 2.
DT   25-MAY-2022, entry version 65.
DE   RecName: Full=Probable fimbrial chaperone EcpB;
DE   Flags: Precursor;
GN   Name=ecpB; Synonyms=matC; OrderedLocusNames=UTI89_C0308;
OS   Escherichia coli (strain UTI89 / UPEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=364106;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UTI89 / UPEC;
RX   PubMed=16585510; DOI=10.1073/pnas.0600938103;
RA   Chen S.L., Hung C.-S., Xu J., Reigstad C.S., Magrini V., Sabo A.,
RA   Blasiar D., Bieri T., Meyer R.R., Ozersky P., Armstrong J.R., Fulton R.S.,
RA   Latreille J.P., Spieth J., Hooton T.M., Mardis E.R., Hultgren S.J.,
RA   Gordon J.I.;
RT   "Identification of genes subject to positive selection in uropathogenic
RT   strains of Escherichia coli: a comparative genomics approach.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:5977-5982(2006).
CC   -!- FUNCTION: Part of the ecpRABCDE operon, which encodes the E.coli common
CC       pilus (ECP). ECP is found in both commensal and pathogenic strains and
CC       plays a dual role in early-stage biofilm development and host cell
CC       recognition (By similarity). {ECO:0000250}.
CC   -!- INDUCTION: Negatively regulated by H-NS. Positively regulated by IHF
CC       and EcpR (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the EcpB/EcpE family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=ABE05809.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; CP000243; ABE05809.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_000716404.1; NC_007946.1.
DR   AlphaFoldDB; Q1RFQ5; -.
DR   SMR; Q1RFQ5; -.
DR   EnsemblBacteria; ABE05809; ABE05809; UTI89_C0308.
DR   KEGG; eci:UTI89_C0308; -.
DR   HOGENOM; CLU_106652_0_0_6; -.
DR   OMA; KENYFVM; -.
DR   Proteomes; UP000001952; Chromosome.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR040695; EcpB_C.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR008962; PapD-like_sf.
DR   Pfam; PF18649; EcpB_C; 1.
DR   SUPFAM; SSF49354; SSF49354; 1.
PE   3: Inferred from homology;
KW   Chaperone; Fimbrium biogenesis; Signal.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000255"
FT   CHAIN           21..222
FT                   /note="Probable fimbrial chaperone EcpB"
FT                   /id="PRO_0000369159"
SQ   SEQUENCE   222 AA;  24501 MW;  F32908C77A181872 CRC64;
     MKKHLLPLAL LFSGISPAQA LDVGDISSFM NSDSSTLSKT IQNSTDSGRL INIRLERLSS
     PLDDGQVIAM DKPDELLLTP ASLLLPAQAS EVIRFFYKGP ADEKERYYRI VWFDQALSDA
     QRDNANRSAV ATASARIGTI LVVAPRQANY HFQYANGSLT NTGNATLRIL AYGPCLKAAN
     GKECKENYYL MPGKSRRFTR VDTADNKGRV ALWQGDKFIP VK