ID   ECPE_ECO57              Reviewed;         236 AA.
AC   Q8X6I6; Q7AHC4;
DT   09-JUL-2014, integrated into UniProtKB/Swiss-Prot.
DT   09-JUL-2014, sequence version 2.
DT   03-AUG-2022, entry version 117.
DE   RecName: Full=Probable fimbrial chaperone EcpE;
DE   Flags: Precursor;
GN   Name=ecpE; Synonyms=yagV; OrderedLocusNames=Z0356, ECs0319;
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T.,
RA   Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T., Kuhara S.,
RA   Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and
RT   genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J.,
RA   Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G.,
RA   Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J.,
RA   Davis N.W., Lim A., Dimalanta E.T., Potamousis K., Apodaca J.,
RA   Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A.,
RA   Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
RN   [3]
RP   INDUCTION.
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=22797761; DOI=10.1128/jb.00915-12;
RA   Martinez-Santos V.I., Medrano-Lopez A., Saldana Z., Giron J.A.,
RA   Puente J.L.;
RT   "Transcriptional regulation of the ecp operon by EcpR, IHF, and H-NS in
RT   attaching and effacing Escherichia coli.";
RL   J. Bacteriol. 194:5020-5033(2012).
CC   -!- FUNCTION: Part of the ecpRABCDE operon, which encodes the E.coli common
CC       pilus (ECP). ECP is found in both commensal and pathogenic strains and
CC       plays a dual role in early-stage biofilm development and host cell
CC       recognition (By similarity). {ECO:0000250}.
CC   -!- INDUCTION: Negatively regulated by H-NS. Positively regulated by IHF
CC       and EcpR. {ECO:0000269|PubMed:22797761}.
CC   -!- SIMILARITY: Belongs to the EcpB/EcpE family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAG54614.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
CC       Sequence=BAB33742.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; AE005174; AAG54614.1; ALT_INIT; Genomic_DNA.
DR   EMBL; BA000007; BAB33742.1; ALT_INIT; Genomic_DNA.
DR   PIR; B85519; B85519.
DR   PIR; G90668; G90668.
DR   RefSeq; NP_308346.2; NC_002695.1.
DR   RefSeq; WP_001301550.1; NZ_SWKA01000005.1.
DR   AlphaFoldDB; Q8X6I6; -.
DR   SMR; Q8X6I6; -.
DR   STRING; 155864.EDL933_0320; -.
DR   EnsemblBacteria; AAG54614; AAG54614; Z0356.
DR   EnsemblBacteria; BAB33742; BAB33742; ECs_0319.
DR   GeneID; 914418; -.
DR   KEGG; ece:Z0356; -.
DR   KEGG; ecs:ECs_0319; -.
DR   PATRIC; fig|386585.9.peg.413; -.
DR   eggNOG; COG3121; Bacteria.
DR   HOGENOM; CLU_106652_0_0_6; -.
DR   OMA; RPREVQF; -.
DR   Proteomes; UP000000558; Chromosome.
DR   Proteomes; UP000002519; Chromosome.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR008962; PapD-like_sf.
DR   SUPFAM; SSF49354; SSF49354; 1.
PE   2: Evidence at transcript level;
KW   Chaperone; Fimbrium biogenesis; Reference proteome; Signal.
FT   SIGNAL          1..27
FT                   /evidence="ECO:0000255"
FT   CHAIN           28..236
FT                   /note="Probable fimbrial chaperone EcpE"
FT                   /id="PRO_0000429539"
SQ   SEQUENCE   236 AA;  26650 MW;  6CA8076BF4A8F96E CRC64;
     MFRRRGVTLT KALLTAVCML AAPLTQAISV GNLTFSLPSE TDFVSKRVVN NNKSARIYRI
     AISAIDSPGS SELRTRPVDG ELLFAPRQLA LQAGESEYFK FYYHGPQDNR ERYYRVSFRE
     VPTRNLTKRS PTGGEVSTEP VVVMDTILVV RPRQVQFKWS FDQVTGTVSN TGNTWFKLLI
     KPGCDSTEEE GDAWYLRPED VVHQPELRQP GNHYLVYNDK FIKISDSCPA KPPSAD