ID   ECPE_ECOLI              Reviewed;         236 AA.
AC   P77263; Q2MCD3;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   15-JUL-1998, sequence version 2.
DT   03-AUG-2022, entry version 128.
DE   RecName: Full=Probable fimbrial chaperone EcpE;
DE   Flags: Precursor;
GN   Name=ecpE; Synonyms=matF, yagV; OrderedLocusNames=b0289, JW5030;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RA   Chung E., Allen E., Araujo R., Aparicio A.M., Davis K., Duncan M.,
RA   Federspiel N., Hyman R., Kalman S., Komp C., Kurdi O., Lew H., Lin D.,
RA   Namath A., Oefner P., Roberts D., Schramm S., Davis R.W.;
RT   "Sequence of minutes 4-25 of Escherichia coli.";
RL   Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
RN   [4]
RP   EXPRESSION.
RC   STRAIN=K12;
RX   PubMed=20522494; DOI=10.1099/mic.0.039610-0;
RA   Lehti T.A., Bauchart P., Heikkinen J., Hacker J., Korhonen T.K.,
RA   Dobrindt U., Westerlund-Wikstrom B.;
RT   "Mat fimbriae promote biofilm formation by meningitis-associated
RT   Escherichia coli.";
RL   Microbiology 156:2408-2417(2010).
CC   -!- FUNCTION: Part of the ecpRABCDE operon, which encodes the E.coli common
CC       pilus (ECP). ECP is found in both commensal and pathogenic strains and
CC       plays a dual role in early-stage biofilm development and host cell
CC       recognition (By similarity). {ECO:0000250}.
CC   -!- INDUCTION: Negatively regulated by H-NS. Positively regulated by IHF
CC       and EcpR (By similarity). {ECO:0000250}.
CC   -!- MISCELLANEOUS: Not expressed under classical laboratory conditions, but
CC       is functional when constitutively expressed.
CC       {ECO:0000305|PubMed:20522494}.
CC   -!- SIMILARITY: Belongs to the EcpB/EcpE family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAB18018.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; U73857; AAB18018.1; ALT_INIT; Genomic_DNA.
DR   EMBL; U00096; AAC73392.2; -; Genomic_DNA.
DR   EMBL; AP009048; BAE76073.1; -; Genomic_DNA.
DR   PIR; A64755; A64755.
DR   RefSeq; NP_414823.2; NC_000913.3.
DR   RefSeq; WP_001350485.1; NZ_SSUW01000013.1.
DR   AlphaFoldDB; P77263; -.
DR   SMR; P77263; -.
DR   BioGRID; 4259789; 7.
DR   STRING; 511145.b0289; -.
DR   PaxDb; P77263; -.
DR   PRIDE; P77263; -.
DR   EnsemblBacteria; AAC73392; AAC73392; b0289.
DR   EnsemblBacteria; BAE76073; BAE76073; BAE76073.
DR   GeneID; 946631; -.
DR   KEGG; ecj:JW5030; -.
DR   KEGG; eco:b0289; -.
DR   PATRIC; fig|511145.12.peg.293; -.
DR   EchoBASE; EB3331; -.
DR   eggNOG; COG3121; Bacteria.
DR   HOGENOM; CLU_106652_0_0_6; -.
DR   OMA; RPREVQF; -.
DR   BioCyc; EcoCyc:G6160-MON; -.
DR   PRO; PR:P77263; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR008962; PapD-like_sf.
DR   SUPFAM; SSF49354; SSF49354; 1.
PE   3: Inferred from homology;
KW   Chaperone; Fimbrium biogenesis; Reference proteome; Signal.
FT   SIGNAL          1..27
FT                   /evidence="ECO:0000255"
FT   CHAIN           28..236
FT                   /note="Probable fimbrial chaperone EcpE"
FT                   /id="PRO_0000013787"
SQ   SEQUENCE   236 AA;  26628 MW;  AE2B9CE465FD3F1E CRC64;
     MFRRRGVTLT KALLTAVCML AAPLTQAISV GNLTFSLPSE TDFVSKRVVN NNKSARIYRI
     AISAIDSPGS SELRTRPVDG ELLFAPRQLA LQAGESEYFK FYYHGPRDNR ERYYRVSFRE
     VPTRNHTRRS PTGGVVSTEP VVVMDTILVV RPRQVQFKWS FDKVTGTVSN TGNTWFKLLI
     KPGCDSTEEE GDAWYLRPGD VVHQPELRQP GNHYLVYNDK FIKISDSCPA KPPSAD