ID   ECPR_SHIBS              Reviewed;         196 AA.
AC   Q325R5;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   06-DEC-2005, sequence version 1.
DT   25-MAY-2022, entry version 92.
DE   RecName: Full=HTH-type transcriptional regulator EcpR;
GN   Name=ecpR; Synonyms=matA; OrderedLocusNames=SBO_0225;
OS   Shigella boydii serotype 4 (strain Sb227).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Shigella.
OX   NCBI_TaxID=300268;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Sb227;
RX   PubMed=16275786; DOI=10.1093/nar/gki954;
RA   Yang F., Yang J., Zhang X., Chen L., Jiang Y., Yan Y., Tang X., Wang J.,
RA   Xiong Z., Dong J., Xue Y., Zhu Y., Xu X., Sun L., Chen S., Nie H., Peng J.,
RA   Xu J., Wang Y., Yuan Z., Wen Y., Yao Z., Shen Y., Qiang B., Hou Y., Yu J.,
RA   Jin Q.;
RT   "Genome dynamics and diversity of Shigella species, the etiologic agents of
RT   bacillary dysentery.";
RL   Nucleic Acids Res. 33:6445-6458(2005).
CC   -!- FUNCTION: Part of the ecpRABCDE operon, which encodes the E.coli common
CC       pilus (ECP). ECP plays a dual role in early-stage biofilm development
CC       and host cell recognition. Positively regulates the expression of the
CC       ecp operon (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the EcpR/MatA family. {ECO:0000305}.
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DR   EMBL; CP000036; ABB64943.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q325R5; -.
DR   SMR; Q325R5; -.
DR   EnsemblBacteria; ABB64943; ABB64943; SBO_0225.
DR   KEGG; sbo:SBO_0225; -.
DR   HOGENOM; CLU_128111_0_0_6; -.
DR   OMA; CIWPAHD; -.
DR   Proteomes; UP000007067; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   CDD; cd06170; LuxR_C_like; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR   InterPro; IPR000792; Tscrpt_reg_LuxR_C.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   Pfam; PF00196; GerE; 1.
DR   PRINTS; PR00038; HTHLUXR.
DR   SMART; SM00421; HTH_LUXR; 1.
DR   SUPFAM; SSF46894; SSF46894; 1.
DR   PROSITE; PS50043; HTH_LUXR_2; 1.
PE   3: Inferred from homology;
KW   Activator; Cytoplasm; DNA-binding; Transcription; Transcription regulation.
FT   CHAIN           1..196
FT                   /note="HTH-type transcriptional regulator EcpR"
FT                   /id="PRO_0000369189"
FT   DOMAIN          138..196
FT                   /note="HTH luxR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00411"
FT   DNA_BIND        162..181
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00411"
SQ   SEQUENCE   196 AA;  23273 MW;  CAB6AFF0919883B7 CRC64;
     MTWQSDYSRD YEVKNHMECQ NRSDKYIWSP HDAYFYKGLS ELIVDIDRLI YLSLEKIRKD
     FVFINLNTDS LSEFINRDNE WLSAVKGKQV VLIAARKSEA LANYWYYNSN IRGVVYAGLS
     RDIRKELAYV INGRFLRKDI KKDKITDREM EIIRMTAQGM QPKSIARIEN CSVKTVYTHR
     RNAEAKLYSK IYKLVQ