ID   ECSB_BACSU              Reviewed;         408 AA.
AC   P55340;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   03-AUG-2022, entry version 115.
DE   RecName: Full=Protein EcsB;
GN   Name=ecsB; Synonyms=prsT, yhaC; OrderedLocusNames=BSU10050;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=8581172; DOI=10.1099/13500872-142-1-71;
RA   Leskela S., Kontinen V.P., Sarvas M.;
RT   "Molecular analysis of an operon in Bacillus subtilis encoding a novel ABC
RT   transporter with a role in exoprotein production, sporulation and
RT   competence.";
RL   Microbiology 142:71-77(1996).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9579061; DOI=10.1099/00221287-144-4-859;
RA   Noback M.A., Holsappel S., Kiewiet R., Terpstra P., Wambutt R., Wedler H.,
RA   Venema G., Bron S.;
RT   "The 172 kb prkA-addAB region from 83 degrees to 97 degrees of the Bacillus
RT   subtilis chromosome contains several dysfunctional genes, the glyB marker,
RT   many genes encoding transporter proteins, and the ubiquitous hit gene.";
RL   Microbiology 144:859-875(1998).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
RN   [4]
RP   ROLE IN FORMATION OF BIOFILMS, AND DISRUPTION PHENOTYPE.
RC   STRAIN=168, and 3610;
RX   PubMed=15175311; DOI=10.1128/jb.186.12.3970-3979.2004;
RA   Branda S.S., Gonzalez-Pastor J.E., Dervyn E., Ehrlich S.D., Losick R.,
RA   Kolter R.;
RT   "Genes involved in formation of structured multicellular communities by
RT   Bacillus subtilis.";
RL   J. Bacteriol. 186:3970-3979(2004).
CC   -!- FUNCTION: Presumed to form part of an ABC-transporter, it may form a
CC       transport channel. {ECO:0000269|PubMed:15175311}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- DISRUPTION PHENOTYPE: Cells form colonies in which certain
CC       architectural features are absent or less prominent than those observed
CC       in wild-type colonies. The Ecs activity could be important for the
CC       development of communities. {ECO:0000269|PubMed:15175311}.
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DR   EMBL; X87807; CAA61075.1; -; Genomic_DNA.
DR   EMBL; Y14077; CAA74408.1; -; Genomic_DNA.
DR   EMBL; AL009126; CAB12845.1; -; Genomic_DNA.
DR   PIR; G69619; G69619.
DR   RefSeq; NP_388886.1; NC_000964.3.
DR   RefSeq; WP_003245169.1; NZ_JNCM01000035.1.
DR   AlphaFoldDB; P55340; -.
DR   STRING; 224308.BSU10050; -.
DR   TCDB; 3.A.1.143.1; the atp-binding cassette (abc) superfamily.
DR   jPOST; P55340; -.
DR   PaxDb; P55340; -.
DR   PRIDE; P55340; -.
DR   EnsemblBacteria; CAB12845; CAB12845; BSU_10050.
DR   GeneID; 939298; -.
DR   KEGG; bsu:BSU10050; -.
DR   PATRIC; fig|224308.179.peg.1081; -.
DR   eggNOG; COG4473; Bacteria.
DR   OMA; RKQRFYR; -.
DR   PhylomeDB; P55340; -.
DR   BioCyc; BSUB:BSU10050-MON; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0030420; P:establishment of competence for transformation; IEA:UniProtKB-KW.
DR   GO; GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
DR   InterPro; IPR010288; EcsB_ABC.
DR   Pfam; PF05975; EcsB; 1.
DR   PIRSF; PIRSF037259; EcsB_ABC; 1.
PE   4: Predicted;
KW   Cell membrane; Competence; Membrane; Reference proteome; Sporulation;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..408
FT                   /note="Protein EcsB"
FT                   /id="PRO_0000086926"
FT   TRANSMEM        30..50
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        53..73
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        111..131
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        134..154
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        180..200
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        284..304
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        308..328
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        351..371
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        374..394
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   408 AA;  47300 MW;  344628E5A3E7DAAE CRC64;
     MNNMLDIWQS RLQEHIKETR TYMKYMLNDH LVIVLIFFLA GAASWYSKWI RDIPAHFPSF
     WVMAVLFSLV LTSSYVRTLL KEADLVFLLP LEAKMEPYLK QAFVYSYVSQ LFPLIALSIV
     AMPLYFAVTP GASLVSYAAV FVQLLLLKAW NQVMEWRTTF QNDRSMKRMD VIIRFAANTL
     VLYFVFQSVY MYALLVYVIM AVLYLYMSSA AKRKTFKWES HIESELRRKQ RFYRIANLFT
     DVPHLRKQAK RRAYLDFLLR LVPFEQRKTF AYMFTRAFLR SSDYLGILVR LTIVFALIIM
     YVSASPLIAA VLTVFAIFIT GIQLLPLFGH FDHLALQELY PVQKETKLKS YFSLLKTALS
     IQALLMSVAS AYAAGLTGFL YALIGSAVLI FVVLPAYMTT RLKKHGKL