EDC1_ASHGO
ID EDC1_ASHGO Reviewed; 355 AA.
AC Q753U4;
DT 01-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 25-MAY-2022, entry version 66.
DE RecName: Full=Enhancer of mRNA-decapping protein 1;
GN Name=EDC1; OrderedLocusNames=AFR231W;
OS Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS (Yeast) (Eremothecium gossypii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX NCBI_TaxID=284811;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX PubMed=15001715; DOI=10.1126/science.1095781;
RA Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA Gaffney T.D., Philippsen P.;
RT "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT cerevisiae genome.";
RL Science 304:304-307(2004).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX PubMed=23749448; DOI=10.1534/g3.112.002881;
RA Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT loci, numerous translocations, lack of transposons, and distinct gene
RT duplications.";
RL G3 (Bethesda) 3:1225-1239(2013).
CC -!- FUNCTION: mRNA-binding protein which stimulates mRNA decapping.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the EDC family. {ECO:0000305}.
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DR EMBL; AE016819; AAS53602.1; -; Genomic_DNA.
DR RefSeq; NP_985778.1; NM_211132.1.
DR AlphaFoldDB; Q753U4; -.
DR SMR; Q753U4; -.
DR EnsemblFungi; AAS53602; AAS53602; AGOS_AFR231W.
DR GeneID; 4622041; -.
DR KEGG; ago:AGOS_AFR231W; -.
DR HOGENOM; CLU_826325_0_0_1; -.
DR InParanoid; Q753U4; -.
DR OMA; TMFINSA; -.
DR Proteomes; UP000000591; Chromosome VI.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW.
PE 3: Inferred from homology;
KW Cytoplasm; mRNA processing; Nonsense-mediated mRNA decay;
KW Reference proteome; RNA-binding.
FT CHAIN 1..355
FT /note="Enhancer of mRNA-decapping protein 1"
FT /id="PRO_0000285356"
FT REGION 1..146
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 210..230
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 301..330
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 19..35
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 37..58
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 89..110
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 355 AA; 37463 MW; 08646B227BB8732F CRC64;
MSSDTMFINS ARLLPTENRK VKQLQRPDRK KHTRGSYAAQ KQQLPNGEQP NFGHGQKQSR
KRGSGRQKGR DGAAGDSANV GLTEDLKQLL SIPSGSAGSE SAQKETSAGQ PATGAVADRK
RSVPAGGPAG KSSSEPASAS SAVDGMPGLG FQSAHVPFSS PVVNHPMLAE PAATGPVLSV
PFPGHVAGYM PCVNNTRVQY PLQTRNNVPM SQPMSQPMSQ PMSQPMSQPM SQPISPYLPQ
GFQMHPQSFV GLPVAPMYPQ YMSAQYQSPK QQSACQMPLR AQPPLIPSIT RNALPCVSSA
NSTAKASVRS KGSPGSEGGS RRSQNWKSSQ NVGYAGATFA TDQPALSSLP KPSFV
