ID   EDC1_CANAL              Reviewed;         264 AA.
AC   Q5ALP1; A0A1D8PGJ2;
DT   01-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   10-MAY-2017, sequence version 2.
DT   03-AUG-2022, entry version 60.
DE   RecName: Full=Enhancer of mRNA-decapping protein 1;
GN   Name=EDC1; OrderedLocusNames=CAALFM_C202190CA;
GN   ORFNames=CaO19.1535, CaO19.9110;
OS   Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX   NCBI_TaxID=237561;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=15123810; DOI=10.1073/pnas.0401648101;
RA   Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B.,
RA   Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W.,
RA   Scherer S.;
RT   "The diploid genome sequence of Candida albicans.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=17419877; DOI=10.1186/gb-2007-8-4-r52;
RA   van het Hoog M., Rast T.J., Martchenko M., Grindle S., Dignard D.,
RA   Hogues H., Cuomo C., Berriman M., Scherer S., Magee B.B., Whiteway M.,
RA   Chibana H., Nantel A., Magee P.T.;
RT   "Assembly of the Candida albicans genome into sixteen supercontigs aligned
RT   on the eight chromosomes.";
RL   Genome Biol. 8:RESEARCH52.1-RESEARCH52.12(2007).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=24025428; DOI=10.1186/gb-2013-14-9-r97;
RA   Muzzey D., Schwartz K., Weissman J.S., Sherlock G.;
RT   "Assembly of a phased diploid Candida albicans genome facilitates allele-
RT   specific measurements and provides a simple model for repeat and indel
RT   structure.";
RL   Genome Biol. 14:RESEARCH97.1-RESEARCH97.14(2013).
CC   -!- FUNCTION: mRNA-binding protein which stimulates mRNA decapping.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the EDC family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP017624; AOW27259.1; -; Genomic_DNA.
DR   RefSeq; XP_722579.2; XM_717486.2.
DR   AlphaFoldDB; Q5ALP1; -.
DR   PRIDE; Q5ALP1; -.
DR   GeneID; 3635753; -.
DR   KEGG; cal:CAALFM_C202190CA; -.
DR   CGD; CAL0000181580; orf19.9110.
DR   VEuPathDB; FungiDB:C2_02190C_A; -.
DR   HOGENOM; CLU_097606_0_0_1; -.
DR   InParanoid; Q5ALP1; -.
DR   OrthoDB; 1628490at2759; -.
DR   PRO; PR:Q5ALP1; -.
DR   Proteomes; UP000000559; Chromosome 2.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW.
PE   3: Inferred from homology;
KW   Cytoplasm; mRNA processing; Nonsense-mediated mRNA decay;
KW   Reference proteome; RNA-binding.
FT   CHAIN           1..264
FT                   /note="Enhancer of mRNA-decapping protein 1"
FT                   /id="PRO_0000285357"
FT   REGION          1..180
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          193..264
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        7..26
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        72..103
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        104..121
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        162..180
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        207..264
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   264 AA;  28928 MW;  2E9FC169872C3B80 CRC64;
     MLAQQQPPTP TPTPQQSQPQ PQPQPQPQQM SQSRKSKSKK KQSYYDEEVR TLPSGAPVDF
     GHGKKSTSKP KSKSKPASSS TTNFKLTASP SLPSGAKPNF QPYKSTSPSP PPPPPPSTQP
     STSTSTSPTP RTSTGNKNHH NRHQSNHSDY DNDHPQLSLP NGKKPNFFNN NNNDKKFSTI
     PFDSSINLIR KQYNNPNTKA IKEKKLDNNN NNNSSNNSNN SNNSNSAYYA GSSFHSSPDA
     LNLPKPSFKS NNGSPRQSSG LRDY