ID   EDC1_CANGA              Reviewed;         353 AA.
AC   Q6FQE3;
DT   01-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 66.
DE   RecName: Full=Enhancer of mRNA-decapping protein 1;
GN   Name=EDC1; OrderedLocusNames=CAGL0I06941g;
OS   Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL
OS   Y-65) (Yeast) (Torulopsis glabrata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC   Nakaseomyces/Candida clade.
OX   NCBI_TaxID=284593;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: mRNA-binding protein which stimulates mRNA decapping.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the EDC family. {ECO:0000305}.
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DR   EMBL; CR380955; CAG60488.1; -; Genomic_DNA.
DR   RefSeq; XP_447551.1; XM_447551.1.
DR   AlphaFoldDB; Q6FQE3; -.
DR   EnsemblFungi; CAG60488; CAG60488; CAGL0I06941g.
DR   GeneID; 2889062; -.
DR   KEGG; cgr:CAGL0I06941g; -.
DR   CGD; CAL0132710; CAGL0I06941g.
DR   VEuPathDB; FungiDB:CAGL0I06941g; -.
DR   eggNOG; ENOG502S7HY; Eukaryota.
DR   HOGENOM; CLU_790324_0_0_1; -.
DR   InParanoid; Q6FQE3; -.
DR   OMA; TMFINSA; -.
DR   Proteomes; UP000002428; Chromosome I.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW.
PE   3: Inferred from homology;
KW   Cytoplasm; mRNA processing; Nonsense-mediated mRNA decay;
KW   Reference proteome; RNA-binding.
FT   CHAIN           1..353
FT                   /note="Enhancer of mRNA-decapping protein 1"
FT                   /id="PRO_0000285358"
FT   REGION          1..100
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          129..156
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          169..189
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          218..253
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          296..353
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..40
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        83..100
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        222..244
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        298..353
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   353 AA;  38469 MW;  7DF3237B325B7788 CRC64;
     MSNDTMYFNS SRRLPTHSRN NSPIVAAKNN SSTRIPALNN KKPSKKTEKD IEQLLSPQQL
     PNGQRPDFGH GPRGGKQTNG AKTKNKKKQD KELQETKDSY DNLTKNLKNL LINPEKTEKT
     VVETLIKSNS NSATATPQKA PNTTQGITNS HGLSQNFSSP LSTPMILPHN LPMNPLGNPN
     FPANNHYLPY NPQQLQQQQQ QQNRLPVGPG PMNFDNFRPG IAPVAPPQPP PGYPPGPNGP
     PPGMPQQLNF NGQPMYYNQP PMPVPNSAFP INQSIGASPT LPRIIPPNPM NYINPALSTP
     PVVKNPTSNG PVTNTKPTNK SKRNSGRKSN TFAGASFATD VPNESNLPKP SFT