ID   EDC1_DEBHA              Reviewed;         352 AA.
AC   Q6BJD4;
DT   01-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   16-DEC-2008, sequence version 2.
DT   25-MAY-2022, entry version 61.
DE   RecName: Full=Enhancer of mRNA-decapping protein 1;
GN   Name=EDC1; OrderedLocusNames=DEHA2G03256g;
OS   Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990
OS   / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Debaryomyces.
OX   NCBI_TaxID=284592;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: mRNA-binding protein which stimulates mRNA decapping.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the EDC family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CR382139; CAG90135.2; -; Genomic_DNA.
DR   RefSeq; XP_461687.2; XM_461687.2.
DR   AlphaFoldDB; Q6BJD4; -.
DR   EnsemblFungi; CAG90135; CAG90135; DEHA2G03256g.
DR   GeneID; 2904555; -.
DR   KEGG; dha:DEHA2G03256g; -.
DR   VEuPathDB; FungiDB:DEHA2G03256g; -.
DR   eggNOG; ENOG502RIVV; Eukaryota.
DR   HOGENOM; CLU_860511_0_0_1; -.
DR   InParanoid; Q6BJD4; -.
DR   OMA; GYINYQY; -.
DR   OrthoDB; 1632916at2759; -.
DR   Proteomes; UP000000599; Chromosome G.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW.
PE   3: Inferred from homology;
KW   Cytoplasm; mRNA processing; Nonsense-mediated mRNA decay;
KW   Reference proteome; RNA-binding.
FT   CHAIN           1..352
FT                   /note="Enhancer of mRNA-decapping protein 1"
FT                   /id="PRO_0000285359"
FT   REGION          1..258
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          277..352
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        70..84
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        92..116
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        125..140
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        149..168
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        172..231
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        277..292
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   352 AA;  38450 MW;  9A8480513DCC57E2 CRC64;
     MMAHELPLSI HTKKSNHNVP PSKAPSAKTN KHKPSKSGSD DRGLPNGGKV DFGNKSGSQT
     NKKSNKKTSK HTSSNTSNNK GVTRVLPDGS KPNFGNESSH QNGGNHKKQN NEPCLPNGEK
     PNFGEGSKSH SKKKNNDHVL PNGEKPNFFN EKSSKKATKP KEKKPLITED TYAGSSFHSS
     PAALNLPKPS FKTSPKTNDA KQHTTEPNYH VNPQVNTPPQ HSVNVPPQHP VTTYPAGNGV
     PNIPTVPSNP TAFPPRNHYA QPGFSYYATP QGYINYQYPQ VPPPPPPQGG VYPMVAPQYQ
     QQPQQHPQQH PQPQPQPQQL PQQHRPHHLP AIAAPQQGHR ISFNELLGSS KS