ID   EDF1_CHICK              Reviewed;         148 AA.
AC   Q5ZMC0;
DT   12-APR-2005, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 107.
DE   RecName: Full=Endothelial differentiation-related factor 1 homolog;
DE            Short=EDF-1;
GN   Name=EDF1; ORFNames=RCJMB04_2j2;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=CB; TISSUE=Bursa of Fabricius;
RX   PubMed=15642098; DOI=10.1186/gb-2004-6-1-r6;
RA   Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P.,
RA   Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P.,
RA   Hayashizaki Y., Buerstedde J.-M.;
RT   "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene
RT   function analysis.";
RL   Genome Biol. 6:R6.1-R6.9(2005).
CC   -!- FUNCTION: Probable transcriptional coactivator. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
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DR   EMBL; AJ719464; CAG31123.1; -; mRNA.
DR   RefSeq; NP_001006203.1; NM_001006203.1.
DR   AlphaFoldDB; Q5ZMC0; -.
DR   SMR; Q5ZMC0; -.
DR   STRING; 9031.ENSGALP00000014641; -.
DR   PaxDb; Q5ZMC0; -.
DR   Ensembl; ENSGALT00000069680; ENSGALP00000058327; ENSGALG00000038003.
DR   GeneID; 417286; -.
DR   KEGG; gga:417286; -.
DR   CTD; 8721; -.
DR   VEuPathDB; HostDB:geneid_417286; -.
DR   eggNOG; KOG3398; Eukaryota.
DR   GeneTree; ENSGT00390000008519; -.
DR   HOGENOM; CLU_112609_0_1_1; -.
DR   InParanoid; Q5ZMC0; -.
DR   OMA; NKAHQGT; -.
DR   OrthoDB; 1571466at2759; -.
DR   PhylomeDB; Q5ZMC0; -.
DR   TreeFam; TF300064; -.
DR   PRO; PR:Q5ZMC0; -.
DR   Proteomes; UP000000539; Chromosome 17.
DR   Bgee; ENSGALG00000038003; Expressed in lung and 14 other tissues.
DR   ExpressionAtlas; Q5ZMC0; baseline and differential.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   CDD; cd00093; HTH_XRE; 1.
DR   Gene3D; 1.10.260.40; -; 1.
DR   InterPro; IPR001387; Cro/C1-type_HTH.
DR   InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR   InterPro; IPR013729; MBF1_N.
DR   Pfam; PF01381; HTH_3; 1.
DR   Pfam; PF08523; MBF1; 1.
DR   SMART; SM00530; HTH_XRE; 1.
DR   SUPFAM; SSF47413; SSF47413; 1.
DR   PROSITE; PS50943; HTH_CROC1; 1.
PE   2: Evidence at transcript level;
KW   Activator; DNA-binding; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..148
FT                   /note="Endothelial differentiation-related factor 1
FT                   homolog"
FT                   /id="PRO_0000149798"
FT   DOMAIN          81..135
FT                   /note="HTH cro/C1-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00257"
FT   DNA_BIND        92..111
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00257"
FT   REGION          1..26
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   148 AA;  16364 MW;  8CE1DD092644B316 CRC64;
     MAESDWDTVT VLRKKGPSAA QAKSKQAVLA AQRRGEDVET SKKWAAGQNK QHFITKNTAK
     LDRETEELHH DRVPLEVGKV IQQGRQSKGM TQKDLATKIN EKPQVIADYE SGRAIPNNQV
     MGKIERAIGL KLRGKDIGKP LETGPKGK