EDL10_ARATH
ID EDL10_ARATH Reviewed; 458 AA.
AC Q93Z80; Q9MAA3;
DT 28-NOV-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-2001, sequence version 1.
DT 03-AUG-2022, entry version 134.
DE RecName: Full=Sugar transporter ERD6-like 10;
GN OrderedLocusNames=At3g05160; ORFNames=T12H1.13;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP GENE FAMILY.
RX PubMed=16923188; DOI=10.1186/1471-2148-6-64;
RA Johnson D.A., Hill J.P., Thomas M.A.;
RT "The monosaccharide transporter gene family in land plants is ancient and
RT shows differential subfamily expression and expansion across lineages.";
RL BMC Evol. Biol. 6:64-64(2006).
CC -!- FUNCTION: Sugar transporter. {ECO:0000305}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000250}; Multi-pass membrane
CC protein {ECO:0000250}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=1;
CC Comment=A number of isoforms are produced. According to EST
CC sequences.;
CC Name=1;
CC IsoId=Q93Z80-1; Sequence=Displayed;
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. Sugar
CC transporter (TC 2.A.1.1) family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAF27022.1; Type=Erroneous gene model prediction; Note=The predicted gene At3g05160 has been split into 2 genes: At3g05160 and At3g05165.; Evidence={ECO:0000305};
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DR EMBL; AC009177; AAF27022.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002686; AEE74193.1; -; Genomic_DNA.
DR EMBL; AY058056; AAL24164.1; -; mRNA.
DR EMBL; BT002699; AAO11615.1; -; mRNA.
DR RefSeq; NP_566247.1; NM_111388.4. [Q93Z80-1]
DR AlphaFoldDB; Q93Z80; -.
DR SMR; Q93Z80; -.
DR STRING; 3702.AT3G05160.1; -.
DR PaxDb; Q93Z80; -.
DR PRIDE; Q93Z80; -.
DR ProteomicsDB; 247062; -. [Q93Z80-1]
DR EnsemblPlants; AT3G05160.1; AT3G05160.1; AT3G05160. [Q93Z80-1]
DR GeneID; 819679; -.
DR Gramene; AT3G05160.1; AT3G05160.1; AT3G05160. [Q93Z80-1]
DR KEGG; ath:AT3G05160; -.
DR Araport; AT3G05160; -.
DR TAIR; locus:2096234; AT3G05160.
DR eggNOG; KOG0254; Eukaryota.
DR OMA; VINWRFL; -.
DR OrthoDB; 430696at2759; -.
DR PhylomeDB; Q93Z80; -.
DR PRO; PR:Q93Z80; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q93Z80; baseline and differential.
DR Genevisible; Q93Z80; AT.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0051119; F:sugar transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0055085; P:transmembrane transport; IBA:GO_Central.
DR CDD; cd17358; MFS_GLUT6_8_Class3_like; 1.
DR Gene3D; 1.20.1250.20; -; 1.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR044775; MFS_ERD6/Tret1-like.
DR InterPro; IPR005828; MFS_sugar_transport-like.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR003663; Sugar/inositol_transpt.
DR InterPro; IPR005829; Sugar_transporter_CS.
DR Pfam; PF00083; Sugar_tr; 1.
DR PRINTS; PR00171; SUGRTRNSPORT.
DR SUPFAM; SSF103473; SSF103473; 1.
DR TIGRFAMs; TIGR00879; SP; 1.
DR PROSITE; PS50850; MFS; 1.
DR PROSITE; PS00216; SUGAR_TRANSPORT_1; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Membrane; Reference proteome; Sugar transport;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..458
FT /note="Sugar transporter ERD6-like 10"
FT /id="PRO_0000259860"
FT TRANSMEM 17..37
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TRANSMEM 66..86
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TRANSMEM 96..116
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TRANSMEM 119..139
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TRANSMEM 150..170
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TRANSMEM 174..194
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT TRANSMEM 257..277
FT /note="Helical; Name=7"
FT /evidence="ECO:0000255"
FT TRANSMEM 292..312
FT /note="Helical; Name=8"
FT /evidence="ECO:0000255"
FT TRANSMEM 319..339
FT /note="Helical; Name=9"
FT /evidence="ECO:0000255"
FT TRANSMEM 350..370
FT /note="Helical; Name=10"
FT /evidence="ECO:0000255"
FT TRANSMEM 393..413
FT /note="Helical; Name=11"
FT /evidence="ECO:0000255"
FT TRANSMEM 419..439
FT /note="Helical; Name=12"
FT /evidence="ECO:0000255"
SQ SEQUENCE 458 AA; 50299 MW; 9FC862BE0D9F9CC7 CRC64;
MEEGLLRHEN DRDDRRITAC VILSTFVAVC SSFSYGCANG YTSGAETAIM KELDLSMAQF
SAFGSFLNLG GAVGALFSGQ LAVILGRRRT LWACDLFCIF GWLSIAFAKN VLWLDLGRIS
LGIGVGLTSY VVPVYIAEIT PKHVRGAFSA STLLLQNSGI SLIYFFGTVI NWRVLAVIGA
LPCFIPVIGI YFIPESPRWL AKIGSVKEVE NSLHRLRGKD ADVSDEAAEI QVMTKMLEED
SKSSFCDMFQ KKYRRTLVVG IGLMLIQQLS GASGITYYSN AIFRKAGFSE RLGSMIFGVF
VIPKALVGLI LVDRWGRRPL LLASAVGMSI GSLLIGVSFT LQEMNLFPEF IPVFVFINIL
VYFGFFAIGI GGLPWIIMSE IFPINIKVSA GSIVALTSWT TGWFVSYGFN FMFEWSAQGT
FYIFAMVGGL SLLFIWMLVP ETKGQSLEEL QASLTGTT
