EDL11_ARATH
ID EDL11_ARATH Reviewed; 467 AA.
AC Q94AF9; Q9MAA3;
DT 28-NOV-2006, integrated into UniProtKB/Swiss-Prot.
DT 28-NOV-2006, sequence version 2.
DT 03-AUG-2022, entry version 125.
DE RecName: Full=Sugar transporter ERD6-like 11;
GN OrderedLocusNames=At3g05165; ORFNames=T12H1.13;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP GENE FAMILY.
RX PubMed=16923188; DOI=10.1186/1471-2148-6-64;
RA Johnson D.A., Hill J.P., Thomas M.A.;
RT "The monosaccharide transporter gene family in land plants is ancient and
RT shows differential subfamily expression and expansion across lineages.";
RL BMC Evol. Biol. 6:64-64(2006).
CC -!- FUNCTION: Sugar transporter. {ECO:0000305}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000250}; Multi-pass membrane
CC protein {ECO:0000250}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q94AF9-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q94AF9-2; Sequence=VSP_021551;
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. Sugar
CC transporter (TC 2.A.1.1) family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAF27022.1; Type=Erroneous gene model prediction; Note=The predicted gene At3g05160 has been split into 2 genes: At3g05160 and At3g05165.; Evidence={ECO:0000305};
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DR EMBL; AC009177; AAF27022.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002686; AEE74195.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE74196.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE74197.1; -; Genomic_DNA.
DR EMBL; AY048207; AAK82470.1; -; mRNA.
DR EMBL; AY077661; AAL76139.1; -; mRNA.
DR RefSeq; NP_001030640.1; NM_001035563.2. [Q94AF9-1]
DR RefSeq; NP_566248.1; NM_111389.2. [Q94AF9-1]
DR RefSeq; NP_974225.1; NM_202496.2. [Q94AF9-1]
DR AlphaFoldDB; Q94AF9; -.
DR SMR; Q94AF9; -.
DR BioGRID; 5015; 1.
DR IntAct; Q94AF9; 1.
DR STRING; 3702.AT3G05165.2; -.
DR PaxDb; Q94AF9; -.
DR ProteomicsDB; 247063; -. [Q94AF9-1]
DR EnsemblPlants; AT3G05165.1; AT3G05165.1; AT3G05165. [Q94AF9-1]
DR EnsemblPlants; AT3G05165.2; AT3G05165.2; AT3G05165. [Q94AF9-1]
DR EnsemblPlants; AT3G05165.3; AT3G05165.3; AT3G05165. [Q94AF9-1]
DR GeneID; 819680; -.
DR Gramene; AT3G05165.1; AT3G05165.1; AT3G05165. [Q94AF9-1]
DR Gramene; AT3G05165.2; AT3G05165.2; AT3G05165. [Q94AF9-1]
DR Gramene; AT3G05165.3; AT3G05165.3; AT3G05165. [Q94AF9-1]
DR KEGG; ath:AT3G05165; -.
DR Araport; AT3G05165; -.
DR TAIR; locus:505006329; AT3G05165.
DR eggNOG; KOG0254; Eukaryota.
DR HOGENOM; CLU_001265_30_5_1; -.
DR InParanoid; Q94AF9; -.
DR OMA; VINWRLL; -.
DR PhylomeDB; Q94AF9; -.
DR PRO; PR:Q94AF9; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q94AF9; baseline and differential.
DR Genevisible; Q94AF9; AT.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0051119; F:sugar transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0055085; P:transmembrane transport; IBA:GO_Central.
DR CDD; cd17358; MFS_GLUT6_8_Class3_like; 1.
DR Gene3D; 1.20.1250.20; -; 1.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR044775; MFS_ERD6/Tret1-like.
DR InterPro; IPR005828; MFS_sugar_transport-like.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR003663; Sugar/inositol_transpt.
DR InterPro; IPR005829; Sugar_transporter_CS.
DR Pfam; PF00083; Sugar_tr; 1.
DR PRINTS; PR00171; SUGRTRNSPORT.
DR SUPFAM; SSF103473; SSF103473; 1.
DR TIGRFAMs; TIGR00879; SP; 1.
DR PROSITE; PS50850; MFS; 1.
DR PROSITE; PS00216; SUGAR_TRANSPORT_1; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Membrane; Reference proteome; Sugar transport;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..467
FT /note="Sugar transporter ERD6-like 11"
FT /id="PRO_0000259861"
FT TRANSMEM 26..46
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TRANSMEM 75..95
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TRANSMEM 105..125
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TRANSMEM 128..148
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TRANSMEM 155..177
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TRANSMEM 183..203
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT TRANSMEM 266..286
FT /note="Helical; Name=7"
FT /evidence="ECO:0000255"
FT TRANSMEM 301..321
FT /note="Helical; Name=8"
FT /evidence="ECO:0000255"
FT TRANSMEM 328..348
FT /note="Helical; Name=9"
FT /evidence="ECO:0000255"
FT TRANSMEM 359..379
FT /note="Helical; Name=10"
FT /evidence="ECO:0000255"
FT TRANSMEM 402..422
FT /note="Helical; Name=11"
FT /evidence="ECO:0000255"
FT TRANSMEM 428..448
FT /note="Helical; Name=12"
FT /evidence="ECO:0000255"
FT VAR_SEQ 1..183
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:14593172"
FT /id="VSP_021551"
SQ SEQUENCE 467 AA; 51293 MW; 47F8BA8FB2BC600D CRC64;
MVVEEENRSM EEGLLQHQND RDDRRITACV ILSTFVAVCS AFSYGCAAGY TSGAETAIMK
ELDLSMAQFS AFGSFLNVGG AVGALFSGQL AVILGRRRTL WACDFFCVFG WLSIAFAKNV
FWLDLGRISL GIGVGLISYV VPVYIAEITP KHVRGAFTAS NQLLQNSGVS LIYFFGTVIN
WRVMAVIGAI PCILQTIGIF FIPESPRWLA KIRLSKEVES SLHRLRGKDT DVSGEAAEIQ
VMTKMLEEDS KSSFSDMFQK KYRRTLVVGI GLMLIQQLSG ASGITYYSNA IFRKAGFSER
LGSMIFGVFV IPKALVGLIL VDRWGRRPLL LASAVGMSIG SLLIGVSFTL QQMNVLPELI
PIFVFVNILV YFGCFAFGIG GLPWVIMSEI FPINIKVSAG TIVALTSWTS GWFVSYAFNF
MFEWSAQGTF YIFAAVGGMS FIFIWMLVPE TKGQSLEELQ ASLTGTS
