EDL17_ARATH
ID EDL17_ARATH Reviewed; 474 AA.
AC Q94CI7; Q94EJ0;
DT 28-NOV-2006, integrated into UniProtKB/Swiss-Prot.
DT 28-NOV-2006, sequence version 2.
DT 03-AUG-2022, entry version 126.
DE RecName: Full=Sugar transporter ERD6-like 17 {ECO:0000303|PubMed:16923188};
DE AltName: Full=Sugar-porter family protein 1 {ECO:0000303|PubMed:11485201};
GN Name=SFP1 {ECO:0000303|PubMed:11485201};
GN OrderedLocusNames=At5g27350 {ECO:0000312|Araport:AT5G27350};
GN ORFNames=F21A20.60 {ECO:0000312|EMBL:AC007123};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY, AND DEVELOPMENTAL STAGE.
RC STRAIN=cv. Landsberg erecta;
RX PubMed=11485201; DOI=10.1023/a:1010639015959;
RA Quirino B.F., Reiter W.-D., Amasino R.M.;
RT "One of two tandem Arabidopsis genes homologous to monosaccharide
RT transporters is senescence-associated.";
RL Plant Mol. Biol. 46:447-457(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130714; DOI=10.1038/35048507;
RA Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E.,
RA Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M.,
RA Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.,
RA Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M.,
RA Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L.,
RA O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D.,
RA Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M.,
RA Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L.,
RA Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B.,
RA Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P.,
RA Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M.,
RA Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D.,
RA Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A.,
RA Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I.,
RA Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T.,
RA Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A.,
RA McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U.,
RA Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W.,
RA Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M.,
RA Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S.,
RA Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G.,
RA Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W.,
RA Bevan M., Fransz P.F.;
RT "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.";
RL Nature 408:823-826(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP GENE FAMILY.
RX PubMed=16923188; DOI=10.1186/1471-2148-6-64;
RA Johnson D.A., Hill J.P., Thomas M.A.;
RT "The monosaccharide transporter gene family in land plants is ancient and
RT shows differential subfamily expression and expansion across lineages.";
RL BMC Evol. Biol. 6:64-64(2006).
RN [6]
RP INDUCTION BY NAC072/RD26.
RC STRAIN=cv. Columbia;
RX PubMed=29659022; DOI=10.1111/nph.15127;
RA Kamranfar I., Xue G.-P., Tohge T., Sedaghatmehr M., Fernie A.R.,
RA Balazadeh S., Mueller-Roeber B.;
RT "Transcription factor RD26 is a key regulator of metabolic reprogramming
RT during dark-induced senescence.";
RL New Phytol. 218:1543-1557(2018).
CC -!- FUNCTION: Sugar transporter. {ECO:0000305}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000250}; Multi-pass membrane
CC protein {ECO:0000250}.
CC -!- TISSUE SPECIFICITY: Expressed in young seedlings.
CC {ECO:0000269|PubMed:11485201}.
CC -!- DEVELOPMENTAL STAGE: Expression increases during senescence with the
CC highest levels in fully senescent leaves.
CC {ECO:0000269|PubMed:11485201}.
CC -!- INDUCTION: Triggered by NAC072/RD26 during senescence.
CC {ECO:0000269|PubMed:29659022}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. Sugar
CC transporter (TC 2.A.1.1) family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAK95268.1; Type=Frameshift; Evidence={ECO:0000305};
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DR EMBL; AY026254; AAK11720.1; -; mRNA.
DR EMBL; AC007123; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CP002688; AED93675.1; -; Genomic_DNA.
DR EMBL; AF410282; AAK95268.1; ALT_FRAME; mRNA.
DR EMBL; AY143858; AAN28797.1; -; mRNA.
DR RefSeq; NP_568493.1; NM_122617.2.
DR AlphaFoldDB; Q94CI7; -.
DR SMR; Q94CI7; -.
DR BioGRID; 18068; 29.
DR IntAct; Q94CI7; 29.
DR STRING; 3702.AT5G27350.1; -.
DR PaxDb; Q94CI7; -.
DR PRIDE; Q94CI7; -.
DR ProteomicsDB; 222062; -.
DR EnsemblPlants; AT5G27350.1; AT5G27350.1; AT5G27350.
DR GeneID; 832794; -.
DR Gramene; AT5G27350.1; AT5G27350.1; AT5G27350.
DR KEGG; ath:AT5G27350; -.
DR Araport; AT5G27350; -.
DR TAIR; locus:2146350; AT5G27350.
DR eggNOG; KOG0254; Eukaryota.
DR HOGENOM; CLU_001265_30_5_1; -.
DR InParanoid; Q94CI7; -.
DR OMA; CTATHWL; -.
DR OrthoDB; 430696at2759; -.
DR PhylomeDB; Q94CI7; -.
DR PRO; PR:Q94CI7; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q94CI7; baseline and differential.
DR Genevisible; Q94CI7; AT.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0051119; F:sugar transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0009624; P:response to nematode; HEP:TAIR.
DR GO; GO:0055085; P:transmembrane transport; IBA:GO_Central.
DR CDD; cd17358; MFS_GLUT6_8_Class3_like; 1.
DR Gene3D; 1.20.1250.20; -; 1.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR044775; MFS_ERD6/Tret1-like.
DR InterPro; IPR005828; MFS_sugar_transport-like.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR003663; Sugar/inositol_transpt.
DR InterPro; IPR005829; Sugar_transporter_CS.
DR Pfam; PF00083; Sugar_tr; 1.
DR PRINTS; PR00171; SUGRTRNSPORT.
DR SUPFAM; SSF103473; SSF103473; 1.
DR TIGRFAMs; TIGR00879; SP; 1.
DR PROSITE; PS50850; MFS; 1.
DR PROSITE; PS00216; SUGAR_TRANSPORT_1; 1.
DR PROSITE; PS00217; SUGAR_TRANSPORT_2; 1.
PE 2: Evidence at transcript level;
KW Membrane; Reference proteome; Sugar transport; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..474
FT /note="Sugar transporter ERD6-like 17"
FT /id="PRO_0000259867"
FT TRANSMEM 27..47
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TRANSMEM 76..96
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TRANSMEM 106..126
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TRANSMEM 129..149
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TRANSMEM 159..180
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TRANSMEM 184..204
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT TRANSMEM 266..286
FT /note="Helical; Name=7"
FT /evidence="ECO:0000255"
FT TRANSMEM 302..322
FT /note="Helical; Name=8"
FT /evidence="ECO:0000255"
FT TRANSMEM 329..349
FT /note="Helical; Name=9"
FT /evidence="ECO:0000255"
FT TRANSMEM 363..383
FT /note="Helical; Name=10"
FT /evidence="ECO:0000255"
FT TRANSMEM 403..423
FT /note="Helical; Name=11"
FT /evidence="ECO:0000255"
FT TRANSMEM 429..449
FT /note="Helical; Name=12"
FT /evidence="ECO:0000255"
FT CONFLICT 122
FT /note="V -> M (in Ref. 1; AAK11720)"
FT /evidence="ECO:0000305"
FT CONFLICT 181
FT /note="T -> N (in Ref. 1; AAK11720)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 474 AA; 51786 MW; A676B32656F7173F CRC64;
MVMEEGRSIE EGLLQLKNKN DDSECRITAC VILSTFVAVC GSFSFGVATG YTSGAETGVM
KDLDLSIAQF SAFGSFATLG AAIGALFCGN LAMVIGRRGT MWVSDFLCIT GWLSIAFAKE
VVLLNFGRII SGIGFGLTSY VVPVYIAEIT PKHVRGTFTF SNQLLQNAGL AMIYFCGNFI
TWRTLALLGA LPCFIQVIGL FFVPESPRWL AKVGSDKELE NSLFRLRGRD ADISREASEI
QVMTKMVEND SKSSFSDLFQ RKYRYTLVVG IGLMLIQQFS GSAAVISYAS TIFRKAGFSV
AIGTTMLGIF VIPKAMIGLI LVDKWGRRPL LMTSAFGMSM TCMLLGVAFT LQKMQLLSEL
TPILSFICVM MYIATYAIGL GGLPWVIMSE IFPINIKVTA GSIVTLVSFS SSSIVTYAFN
FLFEWSTQGT FFIFAGIGGA ALLFIWLLVP ETKGLSLEEI QVSLIHQPDE RNQT
