EEPD1_BOVIN
ID EEPD1_BOVIN Reviewed; 571 AA.
AC Q3MHJ7; Q6Q139;
DT 05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 25-OCT-2005, sequence version 1.
DT 03-AUG-2022, entry version 96.
DE RecName: Full=Endonuclease/exonuclease/phosphatase family domain-containing protein 1;
GN Name=EEPD1;
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Hereford; TISSUE=Hypothalamus;
RG NIH - Mammalian Gene Collection (MGC) project;
RL Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 5-366.
RC STRAIN=Brown Swiss;
RA Oberg E.A., Medrano J.F., DeNise S.K.;
RL Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; BC105212; AAI05213.1; -; mRNA.
DR EMBL; AY568574; AAS77580.1; -; mRNA.
DR RefSeq; NP_001029581.1; NM_001034409.2.
DR RefSeq; XP_010802558.1; XM_010804256.2.
DR RefSeq; XP_015324872.1; XM_015469386.1.
DR AlphaFoldDB; Q3MHJ7; -.
DR SMR; Q3MHJ7; -.
DR STRING; 9913.ENSBTAP00000033621; -.
DR PaxDb; Q3MHJ7; -.
DR PRIDE; Q3MHJ7; -.
DR Ensembl; ENSBTAT00000033712; ENSBTAP00000033621; ENSBTAG00000019065.
DR Ensembl; ENSBTAT00000086669; ENSBTAP00000064585; ENSBTAG00000019065.
DR GeneID; 511767; -.
DR KEGG; bta:511767; -.
DR CTD; 80820; -.
DR VEuPathDB; HostDB:ENSBTAG00000019065; -.
DR VGNC; VGNC:28338; EEPD1.
DR eggNOG; KOG1857; Eukaryota.
DR GeneTree; ENSGT00390000009677; -.
DR HOGENOM; CLU_033721_1_0_1; -.
DR InParanoid; Q3MHJ7; -.
DR OMA; VRVATWS; -.
DR OrthoDB; 814192at2759; -.
DR TreeFam; TF328735; -.
DR Proteomes; UP000009136; Chromosome 4.
DR Bgee; ENSBTAG00000019065; Expressed in bone marrow and 105 other tissues.
DR ExpressionAtlas; Q3MHJ7; baseline and differential.
DR GO; GO:0046658; C:anchored component of plasma membrane; IBA:GO_Central.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR GO; GO:0010875; P:positive regulation of cholesterol efflux; IEA:Ensembl.
DR Gene3D; 3.60.10.10; -; 1.
DR InterPro; IPR004509; Competence_ComEA_HhH.
DR InterPro; IPR036691; Endo/exonu/phosph_ase_sf.
DR InterPro; IPR003583; Hlx-hairpin-Hlx_DNA-bd_motif.
DR InterPro; IPR010994; RuvA_2-like.
DR SMART; SM00278; HhH1; 3.
DR SUPFAM; SSF47781; SSF47781; 2.
DR SUPFAM; SSF56219; SSF56219; 1.
DR TIGRFAMs; TIGR00426; TIGR00426; 1.
PE 2: Evidence at transcript level;
KW Lipoprotein; Myristate; Phosphoprotein; Reference proteome.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0000250|UniProtKB:Q7L9B9"
FT CHAIN 2..571
FT /note="Endonuclease/exonuclease/phosphatase family domain-
FT containing protein 1"
FT /id="PRO_0000317260"
FT DOMAIN 38..67
FT /note="HhH"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 202..228
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 548..571
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 16
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q7L9B9"
FT MOD_RES 21
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q5XI74"
FT MOD_RES 25
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q7L9B9"
FT MOD_RES 106
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q3TGW2"
FT MOD_RES 110
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q7L9B9"
FT MOD_RES 162
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q7L9B9"
FT MOD_RES 175
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q7L9B9"
FT MOD_RES 267
FT /note="Phosphothreonine"
FT /evidence="ECO:0000250|UniProtKB:Q3TGW2"
FT MOD_RES 430
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q7L9B9"
FT LIPID 2
FT /note="N-myristoyl glycine"
FT /evidence="ECO:0000250"
FT CONFLICT 47..49
FT /note="EEE -> KEK (in Ref. 2; AAS77580)"
FT /evidence="ECO:0000305"
FT CONFLICT 230
FT /note="S -> P (in Ref. 2; AAS77580)"
FT /evidence="ECO:0000305"
FT CONFLICT 287
FT /note="V -> M (in Ref. 2; AAS77580)"
FT /evidence="ECO:0000305"
FT CONFLICT 341
FT /note="E -> K (in Ref. 2; AAS77580)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 571 AA; 62787 MW; 8B5898039798FE7F CRC64;
MGSTLGCHRS IPRDPSDLSH SRKFSAACNF SNILVNQERL NINTATEEEL MTLPGVTRAV
ARSIVEYREY IGGFKKVEDL ALVSGVGATK LEQVKFEICV SSKGSSAQHS PSSLRRDLMA
EQQPHHLATA AAVPLTPRVN INTATPAQLM SVRGLTEKMA VSIVDYRREH GPFRSVEDLV
RMGGINAAFL DRIRHQVFAE RSRPPSTHTN GGLTFTAKPH PSPTSLSLQS EDLDLPPGGP
TQIISTRPSV EAFGGTRDGR PVLRLATWNL QGCSVEKANN PGVREVVCMT LLENSIKLLA
VQELLDREAL EKFCVELNQP ILPNIRKWKG PRGCWKAVVS ETPSTQLQKG AGFAGFLWDT
AAGVELRDAA WQESSPGNGH GKPVGPSPYL ARFKVGSHDL TLVNLHLATL TLPGGENLSK
NHSDSHRWAS FTQTLQETLK GEKDVIVLGD FGQGPDSSDY DILRKEKFHH LIPAHTFTNI
STKNPQGSKA LDNIWISKSL KKVFTGHWAV VREGLTNPWI PDNWSWGGVA SEHCPVLAEF
YTEKDWTRKE GPRSGNGLTL ERSEANIKHE R
