ID   EEPD1_DANRE             Reviewed;         550 AA.
AC   Q6TEQ0; Q6P0E2;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 84.
DE   RecName: Full=Endonuclease/exonuclease/phosphatase family domain-containing protein 1;
GN   Name=eepd1; ORFNames=zgc:77395;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Kidney marrow;
RX   PubMed=15520368; DOI=10.1073/pnas.0407241101;
RA   Song H.-D., Sun X.-J., Deng M., Zhang G.-W., Zhou Y., Wu X.-Y., Sheng Y.,
RA   Chen Y., Ruan Z., Jiang C.-L., Fan H.-Y., Zon L.I., Kanki J.P., Liu T.X.,
RA   Look A.T., Chen Z.;
RT   "Hematopoietic gene expression profile in zebrafish kidney marrow.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:16240-16245(2004).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; AY422999; AAQ97975.1; -; mRNA.
DR   EMBL; BC065655; AAH65655.1; -; mRNA.
DR   RefSeq; NP_991322.1; NM_205759.1.
DR   AlphaFoldDB; Q6TEQ0; -.
DR   STRING; 7955.ENSDARP00000095703; -.
DR   PaxDb; Q6TEQ0; -.
DR   PRIDE; Q6TEQ0; -.
DR   GeneID; 402965; -.
DR   KEGG; dre:402965; -.
DR   CTD; 80820; -.
DR   ZFIN; ZDB-GENE-040426-1831; eepd1.
DR   eggNOG; KOG1857; Eukaryota.
DR   InParanoid; Q6TEQ0; -.
DR   OrthoDB; 814192at2759; -.
DR   PhylomeDB; Q6TEQ0; -.
DR   PRO; PR:Q6TEQ0; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Unplaced.
DR   GO; GO:0046658; C:anchored component of plasma membrane; IBA:GO_Central.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR   Gene3D; 3.60.10.10; -; 1.
DR   InterPro; IPR036691; Endo/exonu/phosph_ase_sf.
DR   InterPro; IPR003583; Hlx-hairpin-Hlx_DNA-bd_motif.
DR   InterPro; IPR010994; RuvA_2-like.
DR   SMART; SM00278; HhH1; 3.
DR   SUPFAM; SSF47781; SSF47781; 2.
DR   SUPFAM; SSF56219; SSF56219; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome.
FT   CHAIN           1..550
FT                   /note="Endonuclease/exonuclease/phosphatase family domain-
FT                   containing protein 1"
FT                   /id="PRO_0000317264"
FT   DOMAIN          39..68
FT                   /note="HhH"
FT   REGION          194..216
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        194..214
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        344
FT                   /note="S -> F (in Ref. 2; AAH65655)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        413
FT                   /note="S -> G (in Ref. 2; AAH65655)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        429
FT                   /note="M -> L (in Ref. 2; AAH65655)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   550 AA;  60083 MW;  7C511509DC809F1D CRC64;
     MGGNLGCHRS IPKDPTDFCQ GKRKFSAACN FSNILVNQER LNINTATEEE LMTLPGVNRG
     VAQNIVEYRD CIGGFKKVED LALVSGVGAT KLEAIKLEIC VSSKNSSSNH SPSSLRKEHE
     HLPCTGVNIN TATPPQLMSV RGITEKIAKN IVEFRSVHGP FKSIEDLVKV ANINSSLLDR
     IRFQVFVERS RTPSTNTNGG FTHPSPTSFS VQSDEPDVPL GGPPLVTSVR PCVEPPAGTR
     DGKPVVRVAT WNLQRCSSEK ANNPGVKEVV CMTLLENDIK LLAVQDLADR EALDKFCAEL
     NQPTLCSVRR WKSARGLWKC AVSEKPNGVS NSAPEFSGFL WDCSSGIEMK DSAVLESFTT
     NGNGNPHPQP YLGHFYIGSS ELTLVNVLLT AAPSPTENKR KSTSDDLKTH KLSSGVQETL
     KGERDLLVMG HFGVAPDSSE MEILRKEKLS ALLAPSVFTN ISTRTPQGSR SLDNIWASRS
     LRKTYTGQCS VVREGLTNPW IPDNWSWGGV ASEHCPVVAE FFLDVLKERL CSGPAMPVVE
     RGDSMSKHER