EF113_ARATH
ID EF113_ARATH Reviewed; 212 AA.
AC Q9LYU3;
DT 12-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 25-MAY-2022, entry version 132.
DE RecName: Full=Ethylene-responsive transcription factor ERF113;
DE AltName: Full=Protein RELATED TO AP2 6L {ECO:0000305};
GN Name=ERF113; Synonyms=RP2.6L {ECO:0000303|PubMed:21069430};
GN OrderedLocusNames=At5g13330; ORFNames=T31B5.150;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RA Pan Y., Gong W., Liu D., Fu Q., Mei W.-Q., Song W.-Q., Ma L.-G., Luo J.-C.,
RA Deng X.-W., Zhu Y.-X.;
RT "Molecular cloning, expression, phylogenetic and functional
RT characterization of the Arabidopsis AP2/EREBP transcription factor
RT family.";
RL Submitted (FEB-2004) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130714; DOI=10.1038/35048507;
RA Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E.,
RA Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M.,
RA Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.,
RA Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M.,
RA Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L.,
RA O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D.,
RA Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M.,
RA Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L.,
RA Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B.,
RA Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P.,
RA Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M.,
RA Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D.,
RA Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A.,
RA Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I.,
RA Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T.,
RA Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A.,
RA McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U.,
RA Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W.,
RA Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M.,
RA Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S.,
RA Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G.,
RA Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W.,
RA Bevan M., Fransz P.F.;
RT "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.";
RL Nature 408:823-826(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Cheuk R.F., Chen H., Kim C.J., Shinn P., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP INDUCTION BY SALT STRESS.
RX PubMed=16133218; DOI=10.1007/s00425-005-0010-5;
RA Sun K., Cui Y., Hauser B.A.;
RT "Environmental stress alters genes expression and induces ovule abortion:
RT reactive oxygen species appear as ovules commit to abort.";
RL Planta 222:632-642(2005).
RN [6]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=16407444; DOI=10.1104/pp.105.073783;
RA Nakano T., Suzuki K., Fujimura T., Shinshi H.;
RT "Genome-wide analysis of the ERF gene family in Arabidopsis and rice.";
RL Plant Physiol. 140:411-432(2006).
RN [7]
RP FUNCTION, TISSUE SPECIFICITY, AND INDUCTION.
RX PubMed=21069430; DOI=10.1007/s11103-010-9711-7;
RA Krishnaswamy S., Verma S., Rahman M.H., Kav N.N.;
RT "Functional characterization of four APETALA2-family genes (RAP2.6,
RT RAP2.6L, DREB19 and DREB26) in Arabidopsis.";
RL Plant Mol. Biol. 75:107-127(2011).
RN [8]
RP FUNCTION, AND INDUCTION.
RX PubMed=21911380; DOI=10.1073/pnas.1110443108;
RA Asahina M., Azuma K., Pitaksaringkarn W., Yamazaki T., Mitsuda N.,
RA Ohme-Takagi M., Yamaguchi S., Kamiya Y., Okada K., Nishimura T.,
RA Koshiba T., Yokota T., Kamada H., Satoh S.;
RT "Spatially selective hormonal control of RAP2.6L and ANAC071 transcription
RT factors involved in tissue reunion in Arabidopsis.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:16128-16132(2011).
RN [9]
RP FUNCTION, AND INDUCTION.
RX PubMed=22661072; DOI=10.1007/s11103-012-9936-8;
RA Liu P., Sun F., Gao R., Dong H.;
RT "RAP2.6L overexpression delays waterlogging induced premature senescence by
RT increasing stomatal closure more than antioxidant enzyme activity.";
RL Plant Mol. Biol. 79:609-622(2012).
CC -!- FUNCTION: Transcriptional activator involved in the regulation of plant
CC development and tolerance to abiotic stresses (PubMed:21069430). Acts
CC as positive regulator of tolerance to waterlogging stress. Delays
CC waterlogging-induced premature senescence by regulating stomatal
CC closure and antioxidant enzyme activity. May function through ABI1-
CC mediated abscisic acid (ABA) signaling pathway (PubMed:22661072).
CC Involved in tissue reunion of wounded inflorescence stems. Required for
CC the division of pith cells in the reunion process, which is dependent
CC on polar-transported auxin and the wound-inducible hormones ethylene
CC and jasmonate (PubMed:21911380). Binds to the GCC-box pathogenesis-
CC related promoter element. May be involved in the regulation of gene
CC expression by stress factors and by components of stress signal
CC transduction pathways (By similarity). {ECO:0000250,
CC ECO:0000269|PubMed:21069430, ECO:0000269|PubMed:21911380,
CC ECO:0000269|PubMed:22661072}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00366}.
CC -!- TISSUE SPECIFICITY: Expressed in pollen grains.
CC {ECO:0000269|PubMed:21069430}.
CC -!- INDUCTION: Induced by salt stress (PubMed:16133218, PubMed:21069430).
CC Induced drought stress, jasmonate (JA), salicylic acid (SA), abscisic
CC acid (ABA) and ethylene. Down-regulated by freezing stress
CC (PubMed:21069430). Induced by wounding in the flowering stem
CC (PubMed:21911380). Induced by waterlogging.
CC {ECO:0000269|PubMed:16133218, ECO:0000269|PubMed:21069430,
CC ECO:0000269|PubMed:21911380}.
CC -!- SIMILARITY: Belongs to the AP2/ERF transcription factor family. ERF
CC subfamily. {ECO:0000305}.
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DR EMBL; AY560861; AAT44928.1; -; mRNA.
DR EMBL; AL163491; CAB86640.1; -; Genomic_DNA.
DR EMBL; CP002688; AED91881.1; -; Genomic_DNA.
DR EMBL; BT011609; AAS47615.1; -; mRNA.
DR EMBL; BT012250; AAS76737.1; -; mRNA.
DR PIR; T48580; T48580.
DR RefSeq; NP_196837.1; NM_121336.4.
DR AlphaFoldDB; Q9LYU3; -.
DR SMR; Q9LYU3; -.
DR BioGRID; 16452; 7.
DR IntAct; Q9LYU3; 6.
DR STRING; 3702.AT5G13330.1; -.
DR PaxDb; Q9LYU3; -.
DR PRIDE; Q9LYU3; -.
DR ProteomicsDB; 247071; -.
DR EnsemblPlants; AT5G13330.1; AT5G13330.1; AT5G13330.
DR GeneID; 831174; -.
DR Gramene; AT5G13330.1; AT5G13330.1; AT5G13330.
DR KEGG; ath:AT5G13330; -.
DR Araport; AT5G13330; -.
DR TAIR; locus:2183861; AT5G13330.
DR eggNOG; ENOG502RZR5; Eukaryota.
DR HOGENOM; CLU_042594_0_0_1; -.
DR InParanoid; Q9LYU3; -.
DR OMA; FGMLMAT; -.
DR OrthoDB; 1525125at2759; -.
DR PhylomeDB; Q9LYU3; -.
DR PRO; PR:Q9LYU3; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9LYU3; baseline and differential.
DR Genevisible; Q9LYU3; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IPI:TAIR.
DR GO; GO:0071497; P:cellular response to freezing; IEP:TAIR.
DR GO; GO:0009873; P:ethylene-activated signaling pathway; IEA:UniProtKB-KW.
DR GO; GO:0019760; P:glucosinolate metabolic process; IMP:TAIR.
DR GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:TAIR.
DR GO; GO:0009737; P:response to abscisic acid; IEP:TAIR.
DR GO; GO:0009723; P:response to ethylene; IEP:TAIR.
DR GO; GO:0009753; P:response to jasmonic acid; IEP:TAIR.
DR GO; GO:0009751; P:response to salicylic acid; IEP:TAIR.
DR GO; GO:0009651; P:response to salt stress; IMP:TAIR.
DR GO; GO:0009414; P:response to water deprivation; IEP:TAIR.
DR CDD; cd00018; AP2; 1.
DR Gene3D; 3.30.730.10; -; 1.
DR InterPro; IPR001471; AP2/ERF_dom.
DR InterPro; IPR036955; AP2/ERF_dom_sf.
DR InterPro; IPR016177; DNA-bd_dom_sf.
DR InterPro; IPR044808; ERF_plant.
DR PANTHER; PTHR31190; PTHR31190; 1.
DR Pfam; PF00847; AP2; 1.
DR PRINTS; PR00367; ETHRSPELEMNT.
DR SMART; SM00380; AP2; 1.
DR SUPFAM; SSF54171; SSF54171; 1.
DR PROSITE; PS51032; AP2_ERF; 1.
PE 2: Evidence at transcript level;
KW Activator; DNA-binding; Ethylene signaling pathway; Nucleus;
KW Reference proteome; Stress response; Transcription;
KW Transcription regulation.
FT CHAIN 1..212
FT /note="Ethylene-responsive transcription factor ERF113"
FT /id="PRO_0000290424"
FT DNA_BIND 38..95
FT /note="AP2/ERF"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00366"
FT REGION 1..49
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 96..136
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 169..212
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 16..37
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 97..115
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 169..192
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 212 AA; 24288 MW; E44F2A15BC0DC44B CRC64;
MVSALSRVIE NPTDPPVKQE LDKSDQHQPD QDQPRRRHYR GVRQRPWGKW AAEIRDPKKA
ARVWLGTFET AEEAALAYDR AALKFKGTKA KLNFPERVQG PTTTTTISHA PRGVSESMNS
PPPRPGPPST TTTSWPMTYN QDILQYAQLL TSNNEVDLSY YTSTLFSQPF STPSSSSSSS
QQTQQQQLQQ QQQQREEEEK NYGYNYYNYP RE
