EF114_ARATH
ID EF114_ARATH Reviewed; 248 AA.
AC Q9FH54; B2GVM6;
DT 12-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 128.
DE RecName: Full=Ethylene-responsive transcription factor ERF114 {ECO:0000303|PubMed:16407444};
DE AltName: Full=ERF bud enhancer {ECO:0000303|PubMed:23616605};
GN Name=ERF114 {ECO:0000303|PubMed:16407444};
GN Synonyms=EBE {ECO:0000303|PubMed:23616605};
GN OrderedLocusNames=At5g61890 {ECO:0000312|Araport:AT5G61890};
GN ORFNames=K22G18.1 {ECO:0000312|EMBL:BAB08875.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RA Pan Y., Gong W., Liu D., Fu Q., Mei W.-Q., Song W.-Q., Ma L.-G., Luo J.-C.,
RA Deng X.-W., Zhu Y.-X.;
RT "Molecular cloning, expression, phylogenetic and functional
RT characterization of the Arabidopsis AP2/EREBP transcription factor
RT family.";
RL Submitted (FEB-2004) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10718197; DOI=10.1093/dnares/7.1.31;
RA Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Kotani H.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. X. Sequence
RT features of the regions of 3,076,755 bp covered by sixty P1 and TAC
RT clones.";
RL DNA Res. 7:31-63(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA de los Reyes C., Quan R., Chen H., Bautista V., Kim C.J., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=16407444; DOI=10.1104/pp.105.073783;
RA Nakano T., Suzuki K., Fujimura T., Shinshi H.;
RT "Genome-wide analysis of the ERF gene family in Arabidopsis and rice.";
RL Plant Physiol. 140:411-432(2006).
RN [6]
RP FUNCTION, TISSUE SPECIFICITY, DEVELOPMENTAL STAGE, AND INDUCTION BY
RP DECAPITATION.
RX PubMed=23616605; DOI=10.1104/pp.113.214049;
RA Mehrnia M., Balazadeh S., Zanor M.I., Mueller-Roeber B.;
RT "EBE, an AP2/ERF transcription factor highly expressed in proliferating
RT cells, affects shoot architecture in Arabidopsis.";
RL Plant Physiol. 162:842-857(2013).
RN [7]
RP INTERACTION WITH AHL27 AND AHL29.
RX PubMed=24218605; DOI=10.1073/pnas.1219277110;
RA Zhao J., Favero D.S., Peng H., Neff M.M.;
RT "Arabidopsis thaliana AHL family modulates hypocotyl growth redundantly by
RT interacting with each other via the PPC/DUF296 domain.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:E4688-E4697(2013).
CC -!- FUNCTION: Transcriptional regulator of cell proliferation and axillary
CC bud outgrowth. Involved in maintaining the structure of the shoot
CC apical meristem as well as plastochron and phyllotaxy. Activates
CC several genes involved in cell cycle regulation and dormancy breaking,
CC including CYCD3-3, DPA, and BARD1. Strongly down-regulates DRM1, DRMH1,
CC MARD1 and several genes encoding different types of cell wall-
CC remodeling proteins. {ECO:0000269|PubMed:23616605}.
CC -!- SUBUNIT: Interacts with AHL27 and AHL29. {ECO:0000269|PubMed:24218605}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Strongly expressed in proliferating cells. Detected
CC in root tips, stipules, shoot apex, floral tissues, young siliques and
CC abscission zones. {ECO:0000269|PubMed:23616605}.
CC -!- DEVELOPMENTAL STAGE: Expressed during the S phase of the cell cycle.
CC {ECO:0000269|PubMed:23616605}.
CC -!- INDUCTION: Transiently up-regulated 6 to 15 hours after decapitation.
CC {ECO:0000269|PubMed:23616605}.
CC -!- SIMILARITY: Belongs to the AP2/ERF transcription factor family. ERF
CC subfamily. {ECO:0000305}.
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DR EMBL; AY560862; AAT44929.1; -; mRNA.
DR EMBL; AB022212; BAB08875.1; -; Genomic_DNA.
DR EMBL; CP002688; AED97529.1; -; Genomic_DNA.
DR EMBL; BT031357; ACB88827.1; -; mRNA.
DR RefSeq; NP_200995.1; NM_125582.3.
DR AlphaFoldDB; Q9FH54; -.
DR SMR; Q9FH54; -.
DR BioGRID; 21554; 4.
DR IntAct; Q9FH54; 3.
DR STRING; 3702.AT5G61890.1; -.
DR PaxDb; Q9FH54; -.
DR PRIDE; Q9FH54; -.
DR ProteomicsDB; 224735; -.
DR EnsemblPlants; AT5G61890.1; AT5G61890.1; AT5G61890.
DR GeneID; 836310; -.
DR Gramene; AT5G61890.1; AT5G61890.1; AT5G61890.
DR KEGG; ath:AT5G61890; -.
DR Araport; AT5G61890; -.
DR TAIR; locus:2156171; AT5G61890.
DR eggNOG; ENOG502RZR5; Eukaryota.
DR HOGENOM; CLU_042594_0_2_1; -.
DR InParanoid; Q9FH54; -.
DR OMA; PTHQDQG; -.
DR OrthoDB; 1525125at2759; -.
DR PhylomeDB; Q9FH54; -.
DR PRO; PR:Q9FH54; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9FH54; baseline and differential.
DR Genevisible; Q9FH54; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IPI:TAIR.
DR GO; GO:0050832; P:defense response to fungus; IEP:TAIR.
DR GO; GO:0009873; P:ethylene-activated signaling pathway; IEA:UniProtKB-KW.
DR CDD; cd00018; AP2; 1.
DR Gene3D; 3.30.730.10; -; 1.
DR InterPro; IPR001471; AP2/ERF_dom.
DR InterPro; IPR036955; AP2/ERF_dom_sf.
DR InterPro; IPR016177; DNA-bd_dom_sf.
DR InterPro; IPR044808; ERF_plant.
DR PANTHER; PTHR31190; PTHR31190; 1.
DR Pfam; PF00847; AP2; 1.
DR PRINTS; PR00367; ETHRSPELEMNT.
DR SMART; SM00380; AP2; 1.
DR SUPFAM; SSF54171; SSF54171; 1.
DR PROSITE; PS51032; AP2_ERF; 1.
PE 1: Evidence at protein level;
KW Activator; Developmental protein; DNA-binding; Ethylene signaling pathway;
KW Nucleus; Reference proteome; Transcription; Transcription regulation.
FT CHAIN 1..248
FT /note="Ethylene-responsive transcription factor ERF114"
FT /id="PRO_0000290425"
FT DNA_BIND 89..146
FT /note="AP2/ERF"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00366"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 45..90
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 201..248
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 45..80
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 201..228
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 248 AA; 27726 MW; 0E59F4C8B864B4DA CRC64;
MYGKRPFGGD ESEEREEDEN LFPVFSARSQ HDMRVMVSAL TQVIGNQQSK SHDNISSIDD
NYPSVYNPQD PNQQVAPTHQ DQGDLRRRHY RGVRQRPWGK WAAEIRDPKK AARVWLGTFE
TAESAALAYD EAALKFKGSK AKLNFPERVQ LGSNSTYYSS NQIPQMEPQS IPNYNQYYHD
ASSGDMLSFN LGGGYGSGTG YSMSHDNSTT TAATTSSSSG GSSRQQEEQD YARFWRFGDS
SSSPHSGY