EF118_ARATH
ID EF118_ARATH Reviewed; 324 AA.
AC Q9CA27;
DT 12-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 25-MAY-2022, entry version 124.
DE RecName: Full=Ethylene-responsive transcription factor ERF118;
GN Name=ERF118; OrderedLocusNames=At1g68550; ORFNames=T26J14.12;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=16407444; DOI=10.1104/pp.105.073783;
RA Nakano T., Suzuki K., Fujimura T., Shinshi H.;
RT "Genome-wide analysis of the ERF gene family in Arabidopsis and rice.";
RL Plant Physiol. 140:411-432(2006).
CC -!- FUNCTION: Probably acts as a transcriptional activator. Binds to the
CC GCC-box pathogenesis-related promoter element. May be involved in the
CC regulation of gene expression by stress factors and by components of
CC stress signal transduction pathways (By similarity). {ECO:0000250}.
CC -!- INTERACTION:
CC Q9CA27; O80902: CIPK22; NbExp=5; IntAct=EBI-25513289, EBI-4453230;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the AP2/ERF transcription factor family. ERF
CC subfamily. {ECO:0000305}.
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DR EMBL; AC011915; AAG52393.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE34808.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE34809.1; -; Genomic_DNA.
DR EMBL; AY059782; AAL24130.1; -; mRNA.
DR EMBL; AY091303; AAM14242.1; -; mRNA.
DR PIR; G96709; G96709.
DR RefSeq; NP_177022.1; NM_105526.3.
DR RefSeq; NP_974106.1; NM_202377.1.
DR AlphaFoldDB; Q9CA27; -.
DR SMR; Q9CA27; -.
DR BioGRID; 28405; 1.
DR IntAct; Q9CA27; 1.
DR STRING; 3702.AT1G68550.2; -.
DR PaxDb; Q9CA27; -.
DR PRIDE; Q9CA27; -.
DR EnsemblPlants; AT1G68550.1; AT1G68550.1; AT1G68550.
DR EnsemblPlants; AT1G68550.2; AT1G68550.2; AT1G68550.
DR GeneID; 843184; -.
DR Gramene; AT1G68550.1; AT1G68550.1; AT1G68550.
DR Gramene; AT1G68550.2; AT1G68550.2; AT1G68550.
DR KEGG; ath:AT1G68550; -.
DR Araport; AT1G68550; -.
DR TAIR; locus:2201282; AT1G68550.
DR eggNOG; ENOG502RZ0C; Eukaryota.
DR HOGENOM; CLU_062946_0_0_1; -.
DR InParanoid; Q9CA27; -.
DR OMA; KSICCNS; -.
DR OrthoDB; 998936at2759; -.
DR PhylomeDB; Q9CA27; -.
DR PRO; PR:Q9CA27; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9CA27; baseline and differential.
DR Genevisible; Q9CA27; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IPI:TAIR.
DR GO; GO:0009873; P:ethylene-activated signaling pathway; IEA:UniProtKB-KW.
DR CDD; cd00018; AP2; 1.
DR Gene3D; 3.30.730.10; -; 1.
DR InterPro; IPR001471; AP2/ERF_dom.
DR InterPro; IPR036955; AP2/ERF_dom_sf.
DR InterPro; IPR016177; DNA-bd_dom_sf.
DR Pfam; PF00847; AP2; 1.
DR PRINTS; PR00367; ETHRSPELEMNT.
DR SMART; SM00380; AP2; 1.
DR SUPFAM; SSF54171; SSF54171; 1.
DR PROSITE; PS51032; AP2_ERF; 1.
PE 1: Evidence at protein level;
KW Activator; DNA-binding; Ethylene signaling pathway; Nucleus;
KW Reference proteome; Transcription; Transcription regulation.
FT CHAIN 1..324
FT /note="Ethylene-responsive transcription factor ERF118"
FT /id="PRO_0000290429"
FT DNA_BIND 112..170
FT /note="AP2/ERF"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00366"
FT REGION 1..120
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 53..73
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 79..100
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 324 AA; 35569 MW; 81866683CC03892E CRC64;
MVAIRKEQSL SGVSSEIKKR AKRNTLSSLP QETQPLRKVR IIVNDPYATD DSSSDEEELK
VPKPRKMKRI VREINFPSME VSEQPSESSS QDSTKTDGKI AVSASPAVPR KKPVGVRQRK
WGKWAAEIRD PIKKTRTWLG TFDTLEEAAK AYDAKKLEFD AIVAGNVSTT KRDVSSSETS
QCSRSSPVVP VEQDDTSASA LTCVNNPDDV STVAPTAPTP NVPAGGNKET LFDFDFTNLQ
IPDFGFLAEE QQDLDFDCFL ADDQFDDFGL LDDIQGFEDN GPSALPDFDF ADVEDLQLAD
SSFGFLDQLA PINISCPLKS FAAS