ADRL_SCHPO
ID ADRL_SCHPO Reviewed; 324 AA.
AC Q09749;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1995, sequence version 1.
DT 25-MAY-2022, entry version 125.
DE RecName: Full=ADIPOR-like receptor SPBC12C2.09c;
GN ORFNames=SPBC12C2.09c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
CC -!- FUNCTION: Probable receptor, which may be involved in metabolic
CC pathways that regulate lipid metabolism such as fatty acid oxidation.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the ADIPOR family. {ECO:0000305}.
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DR EMBL; CU329671; CAA90822.1; -; Genomic_DNA.
DR PIR; T39372; T39372.
DR RefSeq; NP_596013.1; NM_001021921.2.
DR AlphaFoldDB; Q09749; -.
DR SMR; Q09749; -.
DR BioGRID; 276475; 5.
DR STRING; 4896.SPBC12C2.09c.1; -.
DR PaxDb; Q09749; -.
DR EnsemblFungi; SPBC12C2.09c.1; SPBC12C2.09c.1:pep; SPBC12C2.09c.
DR GeneID; 2539931; -.
DR KEGG; spo:SPBC12C2.09c; -.
DR PomBase; SPBC12C2.09c; -.
DR VEuPathDB; FungiDB:SPBC12C2.09c; -.
DR eggNOG; KOG0748; Eukaryota.
DR HOGENOM; CLU_023075_2_0_1; -.
DR InParanoid; Q09749; -.
DR OMA; LRKGHMP; -.
DR PhylomeDB; Q09749; -.
DR PRO; PR:Q09749; -.
DR Proteomes; UP000002485; Chromosome II.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; ISO:PomBase.
DR GO; GO:0046872; F:metal ion binding; ISO:PomBase.
DR GO; GO:0038023; F:signaling receptor activity; IBA:GO_Central.
DR GO; GO:0006882; P:cellular zinc ion homeostasis; ISO:PomBase.
DR GO; GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW.
DR InterPro; IPR004254; AdipoR/HlyIII-related.
DR PANTHER; PTHR20855; PTHR20855; 1.
DR Pfam; PF03006; HlyIII; 1.
PE 3: Inferred from homology;
KW Fatty acid metabolism; Lipid metabolism; Membrane; Receptor;
KW Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..324
FT /note="ADIPOR-like receptor SPBC12C2.09c"
FT /id="PRO_0000218833"
FT TOPO_DOM 1..91
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 92..112
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TOPO_DOM 113..122
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 123..143
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TOPO_DOM 144..162
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 163..183
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TOPO_DOM 184..188
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 189..209
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TOPO_DOM 210..221
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 222..242
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TOPO_DOM 243..251
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 252..272
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT TOPO_DOM 273..291
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 292..312
FT /note="Helical; Name=7"
FT /evidence="ECO:0000255"
FT TOPO_DOM 313..324
FT /note="Extracellular"
FT /evidence="ECO:0000255"
SQ SEQUENCE 324 AA; 37171 MW; A3EBECE3C7AB83EF CRC64;
MSESEQLLEK QQDHKWDAAT HADKGITIKT GKIAVSSSDI PLRNRKGLLT WDQLEPWQQD
NQYIISGYRP PSFSFYLCVK SIFHVHNESV NIWTHLFGAI VFLFFIFKSE LILKRDTTTA
EDVYVITVFL FSAFTMLGCS TFYHTISNHS DDVSKFGNKL DYLGIVVMIV GSFIPCLHYA
FACHANFRTL YIGTIIGIGV IVASTCLLDR FRQPEWRPYR ALIFVLMGLF GIFPVIHALK
IFSFSEILVR MGLVWLLLQG LFYIVGAVIY ALRIPEKWSP GKYDVFGSSH QWFHVCVIIA
AFCHFHGVCI AYDYFHERRG CGEM
