ID   EF1B1_CAEEL             Reviewed;         213 AA.
AC   P34460;
DT   01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1994, sequence version 1.
DT   03-AUG-2022, entry version 151.
DE   RecName: Full=Probable elongation factor 1-beta/1-delta 1;
DE            Short=EF-1-beta/delta 1;
GN   Name=eef-1B.1; ORFNames=F54H12.6;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=7906398; DOI=10.1038/368032a0;
RA   Wilson R., Ainscough R., Anderson K., Baynes C., Berks M., Bonfield J.,
RA   Burton J., Connell M., Copsey T., Cooper J., Coulson A., Craxton M.,
RA   Dear S., Du Z., Durbin R., Favello A., Fraser A., Fulton L., Gardner A.,
RA   Green P., Hawkins T., Hillier L., Jier M., Johnston L., Jones M.,
RA   Kershaw J., Kirsten J., Laisster N., Latreille P., Lightning J., Lloyd C.,
RA   Mortimore B., O'Callaghan M., Parsons J., Percy C., Rifken L., Roopra A.,
RA   Saunders D., Shownkeen R., Sims M., Smaldon N., Smith A., Smith M.,
RA   Sonnhammer E., Staden R., Sulston J., Thierry-Mieg J., Thomas K.,
RA   Vaudin M., Vaughan K., Waterston R., Watson A., Weinstock L.,
RA   Wilkinson-Sproat J., Wohldman P.;
RT   "2.2 Mb of contiguous nucleotide sequence from chromosome III of C.
RT   elegans.";
RL   Nature 368:32-38(1994).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
RN   [3]
RP   PROTEIN SEQUENCE OF 110-116; 151-172 AND 185-193, AND IDENTIFICATION BY
RP   MASS SPECTROMETRY.
RA   Bienvenut W.V.;
RL   Submitted (SEP-2005) to UniProtKB.
CC   -!- FUNCTION: EF-1-beta and EF-1-delta stimulate the exchange of GDP bound
CC       to EF-1-alpha to GTP.
CC   -!- SUBUNIT: EF-1 is composed of 4 subunits: alpha, beta, delta, and gamma.
CC   -!- SIMILARITY: Belongs to the EF-1-beta/EF-1-delta family. {ECO:0000305}.
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DR   EMBL; FO080401; CCD63459.1; -; Genomic_DNA.
DR   PIR; S44832; S44832.
DR   RefSeq; NP_498737.1; NM_066336.5.
DR   AlphaFoldDB; P34460; -.
DR   SMR; P34460; -.
DR   BioGRID; 41326; 78.
DR   DIP; DIP-24506N; -.
DR   STRING; 6239.F54H12.6; -.
DR   iPTMnet; P34460; -.
DR   EPD; P34460; -.
DR   PaxDb; P34460; -.
DR   PeptideAtlas; P34460; -.
DR   EnsemblMetazoa; F54H12.6.1; F54H12.6.1; WBGene00018846.
DR   GeneID; 176120; -.
DR   KEGG; cel:CELE_F54H12.6; -.
DR   UCSC; F54H12.6; c. elegans.
DR   CTD; 176120; -.
DR   WormBase; F54H12.6; CE00548; WBGene00018846; eef-1B.1.
DR   eggNOG; KOG1668; Eukaryota.
DR   GeneTree; ENSGT00950000183014; -.
DR   HOGENOM; CLU_050172_0_2_1; -.
DR   InParanoid; P34460; -.
DR   OMA; WSYTDSK; -.
DR   OrthoDB; 1464823at2759; -.
DR   PhylomeDB; P34460; -.
DR   PRO; PR:P34460; -.
DR   Proteomes; UP000001940; Chromosome III.
DR   Bgee; WBGene00018846; Expressed in germ line (C elegans) and 4 other tissues.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0005853; C:eukaryotic translation elongation factor 1 complex; IEA:InterPro.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IBA:GO_Central.
DR   GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0006414; P:translational elongation; IBA:GO_Central.
DR   CDD; cd00292; EF1B; 1.
DR   Gene3D; 3.30.70.60; -; 1.
DR   InterPro; IPR036219; eEF-1beta-like_sf.
DR   InterPro; IPR018940; EF-1_beta_acid_region_euk.
DR   InterPro; IPR014038; EF1B_bsu/dsu_GNE.
DR   InterPro; IPR036282; Glutathione-S-Trfase_C_sf.
DR   InterPro; IPR014717; Transl_elong_EF1B/ribosomal_S6.
DR   InterPro; IPR001326; Transl_elong_EF1B_B/D_CS.
DR   Pfam; PF10587; EF-1_beta_acid; 1.
DR   Pfam; PF00736; EF1_GNE; 1.
DR   SMART; SM01182; EF-1_beta_acid; 1.
DR   SMART; SM00888; EF1_GNE; 1.
DR   SUPFAM; SSF47616; SSF47616; 1.
DR   SUPFAM; SSF54984; SSF54984; 1.
DR   PROSITE; PS00824; EF1BD_1; 1.
DR   PROSITE; PS00825; EF1BD_2; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Elongation factor; Protein biosynthesis;
KW   Reference proteome.
FT   CHAIN           1..213
FT                   /note="Probable elongation factor 1-beta/1-delta 1"
FT                   /id="PRO_0000155043"
SQ   SEQUENCE   213 AA;  22704 MW;  6AEFF7B9D08F6DDF CRC64;
     MVADVKSPAG LAAFNTTLAE QAFATGFVLS GEDAQLFAAL GSAPNASTYP NVARWYANVA
     SYTDAERKTW ASAGGSAPAA AAADGDDFDL FGSDDEEEDA EKAKIVEERL AAYAEKKAKK
     AGPIAKSSVI LDVKPWDDET DLGEMEKLVR SIEMDGLVWG GAKLIPIGYG IKKLQIITVI
     EDLKVSVDDL IEKITGDFED HVQSVDIVAF NKI