ID   EF1G_DANRE              Reviewed;         442 AA.
AC   Q6PE25;
DT   09-NOV-2004, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 107.
DE   RecName: Full=Elongation factor 1-gamma;
DE            Short=EF-1-gamma;
DE   AltName: Full=eEF-1B gamma;
GN   Name=eef1g;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Kidney marrow;
RX   PubMed=15520368; DOI=10.1073/pnas.0407241101;
RA   Song H.-D., Sun X.-J., Deng M., Zhang G.-W., Zhou Y., Wu X.-Y., Sheng Y.,
RA   Chen Y., Ruan Z., Jiang C.-L., Fan H.-Y., Zon L.I., Kanki J.P., Liu T.X.,
RA   Look A.T., Chen Z.;
RT   "Hematopoietic gene expression profile in zebrafish kidney marrow.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:16240-16245(2004).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Kidney;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (SEP-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Probably plays a role in anchoring the complex to other
CC       cellular components.
CC   -!- SUBUNIT: EF-1 is composed of four subunits: alpha, beta, delta, and
CC       gamma.
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DR   EMBL; AY394968; AAQ94595.1; -; mRNA.
DR   EMBL; BC058315; AAH58315.1; -; mRNA.
DR   AlphaFoldDB; Q6PE25; -.
DR   SMR; Q6PE25; -.
DR   STRING; 7955.ENSDARP00000072983; -.
DR   PaxDb; Q6PE25; -.
DR   Ensembl; ENSDART00000078522; ENSDARP00000072983; ENSDARG00000056119.
DR   ZFIN; ZDB-GENE-020423-3; eef1g.
DR   eggNOG; KOG0867; Eukaryota.
DR   eggNOG; KOG1627; Eukaryota.
DR   GeneTree; ENSGT00390000007552; -.
DR   InParanoid; Q6PE25; -.
DR   OMA; TRWYETI; -.
DR   PhylomeDB; Q6PE25; -.
DR   Reactome; R-DRE-156842; Eukaryotic Translation Elongation.
DR   PRO; PR:Q6PE25; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Chromosome 14.
DR   Bgee; ENSDARG00000056119; Expressed in muscle tissue and 29 other tissues.
DR   ExpressionAtlas; Q6PE25; baseline.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0006749; P:glutathione metabolic process; IEA:InterPro.
DR   GO; GO:0006414; P:translational elongation; IBA:GO_Central.
DR   Gene3D; 3.30.70.1010; -; 1.
DR   InterPro; IPR001662; EF1B_G_C.
DR   InterPro; IPR036433; EF1B_G_C_sf.
DR   InterPro; IPR010987; Glutathione-S-Trfase_C-like.
DR   InterPro; IPR036282; Glutathione-S-Trfase_C_sf.
DR   InterPro; IPR040079; Glutathione_S-Trfase.
DR   InterPro; IPR004045; Glutathione_S-Trfase_N.
DR   InterPro; IPR004046; GST_C.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   Pfam; PF00647; EF1G; 1.
DR   Pfam; PF00043; GST_C; 1.
DR   Pfam; PF02798; GST_N; 1.
DR   SFLD; SFLDS00019; Glutathione_Transferase_(cytos; 1.
DR   SMART; SM01183; EF1G; 1.
DR   SUPFAM; SSF47616; SSF47616; 1.
DR   SUPFAM; SSF52833; SSF52833; 1.
DR   SUPFAM; SSF89942; SSF89942; 1.
DR   PROSITE; PS50040; EF1G_C; 1.
DR   PROSITE; PS50405; GST_CTER; 1.
DR   PROSITE; PS50404; GST_NTER; 1.
PE   2: Evidence at transcript level;
KW   Elongation factor; Protein biosynthesis; Reference proteome.
FT   CHAIN           1..442
FT                   /note="Elongation factor 1-gamma"
FT                   /id="PRO_0000208818"
FT   DOMAIN          2..87
FT                   /note="GST N-terminal"
FT   DOMAIN          88..216
FT                   /note="GST C-terminal"
FT   DOMAIN          281..442
FT                   /note="EF-1-gamma C-terminal"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00519"
FT   REGION          227..273
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   442 AA;  50457 MW;  649D14FBEC848BF3 CRC64;
     MAAGTLYTYP ENWRAFKAQI AAQYSGARLK IASAPPAFTF GQTNRSPAFL GNFPLGKVPA
     YQGDDGFCLF ESNAIAHYLS NDVLRGSTPQ ASAQVLQWVS FADSEVIPPA SAWVFPTLGI
     MQFNKQATEQ AKEEVKRVLA VLNQHLNTRT FLVGERISLA DITVVCSLLW LYKQVLEPAF
     RQPYPNVTRW FVTCVNQPQF KTVLGEVKLC EKMAQFDAKK FAEMQPKKEA PIKKEKGGKE
     GGKQQPQQQE KKEKKKEEKK AAPAEEEMDE CEAALASEPK AKDPFAHLPK SSFVMDEFKR
     KYSNEDTMTV ALPYFWDHFD REGFSIWYAE YRFPEELTMA FMSCNLITGM FQRLDKLRKN
     AFASVILFGA NNDSCISGIW VFRGQDLAFP LSDDWQIDYE SYTWRKLDVD SEECKTMVKE
     YFAWEGEFKH VGKPFNQGKI FK