ID   EF4L1_ARATH             Reviewed;         125 AA.
AC   O80877;
DT   31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   03-AUG-2022, entry version 102.
DE   RecName: Full=Protein ELF4-LIKE 1;
GN   Name=EFL1; Synonyms=ELF4-L1; OrderedLocusNames=At2g29950;
GN   ORFNames=F23F1.13;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10617197; DOI=10.1038/45471;
RA   Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA   Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA   Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA   Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA   Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA   Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA   Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT   "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL   Nature 402:761-768(1999).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RA   Underwood B.A., Xiao Y.-L., Moskal W.A. Jr., Monaghan E.L., Wang W.,
RA   Redman J.C., Wu H.C., Utterback T., Town C.D.;
RL   Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=16244158; DOI=10.1104/pp.105.063479;
RA   Xiao Y.-L., Smith S.R., Ishmael N., Redman J.C., Kumar N., Monaghan E.L.,
RA   Ayele M., Haas B.J., Wu H.C., Town C.D.;
RT   "Analysis of the cDNAs of hypothetical genes on Arabidopsis chromosome 2
RT   reveals numerous transcript variants.";
RL   Plant Physiol. 139:1323-1337(2005).
RN   [5]
RP   GENE FAMILY.
RX   PubMed=14605220; DOI=10.1104/pp.103.030007;
RA   Khanna R., Kikis E.A., Quail P.H.;
RT   "EARLY FLOWERING 4 functions in phytochrome B-regulated seedling de-
RT   etiolation.";
RL   Plant Physiol. 133:1530-1538(2003).
RN   [6]
RP   FUNCTION, GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=20357892; DOI=10.2976/1.3218766;
RA   Kolmos E., Nowak M., Werner M., Fischer K., Schwarz G., Mathews S.,
RA   Schoof H., Nagy F., Bujnicki J.M., Davis S.J.;
RT   "Integrating ELF4 into the circadian system through combined structural and
RT   functional studies.";
RL   HFSP J. 3:350-366(2009).
CC   -!- FUNCTION: Component of the central CCA1/LHY-TOC1 feedback loop in the
CC       circadian clock that promotes clock accuracy and is required for
CC       sustained rhythms in the absence of daily light/dark cycles.
CC       {ECO:0000269|PubMed:20357892}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the EARLY FLOWERING 4 family. {ECO:0000305}.
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DR   EMBL; AC004680; AAC31857.1; -; Genomic_DNA.
DR   EMBL; CP002685; AEC08326.1; -; Genomic_DNA.
DR   EMBL; AY954806; AAX55132.1; -; Genomic_DNA.
DR   EMBL; AY648325; AAT68736.1; -; mRNA.
DR   PIR; T02490; T02490.
DR   RefSeq; NP_180556.1; NM_128549.3.
DR   AlphaFoldDB; O80877; -.
DR   SMR; O80877; -.
DR   STRING; 3702.AT2G29950.1; -.
DR   PaxDb; O80877; -.
DR   PRIDE; O80877; -.
DR   ProteomicsDB; 247079; -.
DR   EnsemblPlants; AT2G29950.1; AT2G29950.1; AT2G29950.
DR   GeneID; 817545; -.
DR   Gramene; AT2G29950.1; AT2G29950.1; AT2G29950.
DR   KEGG; ath:AT2G29950; -.
DR   Araport; AT2G29950; -.
DR   TAIR; locus:2045673; AT2G29950.
DR   HOGENOM; CLU_119738_2_0_1; -.
DR   InParanoid; O80877; -.
DR   OMA; LNKDDDH; -.
DR   PhylomeDB; O80877; -.
DR   PRO; PR:O80877; -.
DR   Proteomes; UP000006548; Chromosome 2.
DR   ExpressionAtlas; O80877; baseline and differential.
DR   GO; GO:0005634; C:nucleus; ISS:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.
DR   GO; GO:0009649; P:entrainment of circadian clock; IBA:GO_Central.
DR   GO; GO:0042753; P:positive regulation of circadian rhythm; IMP:UniProtKB.
DR   GO; GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.
DR   InterPro; IPR040462; EARLY_FLOWERING_4.
DR   InterPro; IPR009741; EARLY_FLOWERING_4_dom.
DR   PANTHER; PTHR33469; PTHR33469; 1.
DR   Pfam; PF07011; Elf4; 1.
PE   2: Evidence at transcript level;
KW   Biological rhythms; Nucleus; Reference proteome.
FT   CHAIN           1..125
FT                   /note="Protein ELF4-LIKE 1"
FT                   /id="PRO_0000408503"
FT   REGION          1..28
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..17
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   125 AA;  14080 MW;  704CC832643608D5 CRC64;
     MEASRNRSLV GNNRSPEMNE NDGEDVAASA AVEDVEVWDT LSNGFKRAQL YLDQNRDLIQ
     RVNENHMSRI PDNVSRNVGL INEINGNISQ VMEIYSDLSL NFAKKFDQRR RTTKDGDTTT
     TTTGS