ID   EFC10_HUMAN             Reviewed;         127 AA.
AC   A6NFE3;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   15-JAN-2008, sequence version 2.
DT   03-AUG-2022, entry version 102.
DE   RecName: Full=EF-hand calcium-binding domain-containing protein 10;
GN   Name=EFCAB10;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12853948; DOI=10.1038/nature01782;
RA   Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H.,
RA   Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R., Wylie K.,
RA   Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E., Fewell G.A.,
RA   Delehaunty K.D., Miner T.L., Nash W.E., Cordes M., Du H., Sun H.,
RA   Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A., Vanbrunt A.,
RA   Nguyen C., Du F., Lamar B., Courtney L., Kalicki J., Ozersky P.,
RA   Bielicki L., Scott K., Holmes A., Harkins R., Harris A., Strong C.M.,
RA   Hou S., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Leonard S.,
RA   Rohlfing T., Rock S.M., Tin-Wollam A.-M., Abbott A., Minx P., Maupin R.,
RA   Strowmatt C., Latreille P., Miller N., Johnson D., Murray J.,
RA   Woessner J.P., Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W.,
RA   Spieth J., Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E.,
RA   Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Bedell J.A.,
RA   Mardis E.R., Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E.,
RA   Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K., Simms E.,
RA   Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S., Baertsch R.A.,
RA   Brent M.R., Keibler E., Flicek P., Bork P., Suyama M., Bailey J.A.,
RA   Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R., Eddy S.R.,
RA   McPherson J.D., Olson M.V., Eichler E.E., Green E.D., Waterston R.H.,
RA   Wilson R.K.;
RT   "The DNA sequence of human chromosome 7.";
RL   Nature 424:157-164(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
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DR   EMBL; AC073073; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; BC105284; -; NOT_ANNOTATED_CDS; mRNA.
DR   CCDS; CCDS87537.1; -.
DR   AlphaFoldDB; A6NFE3; -.
DR   STRING; 9606.ENSP00000418678; -.
DR   BioMuta; EFCAB10; -.
DR   MassIVE; A6NFE3; -.
DR   PaxDb; A6NFE3; -.
DR   PeptideAtlas; A6NFE3; -.
DR   PRIDE; A6NFE3; -.
DR   ProteomicsDB; 1046; -.
DR   Antibodypedia; 9327; 19 antibodies from 8 providers.
DR   Ensembl; ENST00000480514.6; ENSP00000418678.1; ENSG00000185055.11.
DR   MANE-Select; ENST00000480514.6; ENSP00000418678.1; NM_001355526.2; NP_001342455.1.
DR   UCSC; uc003vdb.4; human.
DR   GeneCards; EFCAB10; -.
DR   HGNC; HGNC:34531; EFCAB10.
DR   HPA; ENSG00000185055; Tissue enhanced (fallopian tube, testis).
DR   neXtProt; NX_A6NFE3; -.
DR   OpenTargets; ENSG00000185055; -.
DR   VEuPathDB; HostDB:ENSG00000185055; -.
DR   eggNOG; ENOG502S6BT; Eukaryota.
DR   GeneTree; ENSGT00940000154487; -.
DR   InParanoid; A6NFE3; -.
DR   OMA; ISFAQYK; -.
DR   PhylomeDB; A6NFE3; -.
DR   SignaLink; A6NFE3; -.
DR   ChiTaRS; EFCAB10; human.
DR   Pharos; A6NFE3; Tdark.
DR   PRO; PR:A6NFE3; -.
DR   Proteomes; UP000005640; Chromosome 7.
DR   RNAct; A6NFE3; protein.
DR   Bgee; ENSG00000185055; Expressed in right uterine tube and 96 other tissues.
DR   ExpressionAtlas; A6NFE3; baseline and differential.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   InterPro; IPR011992; EF-hand-dom_pair.
DR   InterPro; IPR002048; EF_hand_dom.
DR   InterPro; IPR039879; EFC10.
DR   PANTHER; PTHR21847; PTHR21847; 1.
DR   SUPFAM; SSF47473; SSF47473; 1.
DR   PROSITE; PS50222; EF_HAND_2; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome.
FT   CHAIN           1..127
FT                   /note="EF-hand calcium-binding domain-containing protein
FT                   10"
FT                   /id="PRO_0000340680"
FT   DOMAIN          63..98
FT                   /note="EF-hand"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
SQ   SEQUENCE   127 AA;  14721 MW;  82EC94BBE8F1C84B CRC64;
     METSSRELQA AEYLEKHQIK EVVSYLTSAL LFFRPEKPKE YLISLLERLR IAKVTGVAFP
     FFMDNSNIVA MFEMMDSSGR GTISFVQYKE ALKTLGLCTE DEDLQDDGHK ITLDKFKEEV
     NKRMKEI