ID   EFC11_DANRE             Reviewed;         167 AA.
AC   Q568G4;
DT   15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   10-MAY-2005, sequence version 1.
DT   03-AUG-2022, entry version 87.
DE   RecName: Full=EF-hand calcium-binding domain-containing protein 11;
GN   Name=efcab11; ORFNames=zgc:110317;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Olfactory epithelium;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; BC092868; AAH92868.1; -; mRNA.
DR   RefSeq; NP_001017812.1; NM_001017812.1.
DR   AlphaFoldDB; Q568G4; -.
DR   SMR; Q568G4; -.
DR   STRING; 7955.ENSDARP00000064232; -.
DR   PaxDb; Q568G4; -.
DR   GeneID; 550510; -.
DR   KEGG; dre:550510; -.
DR   CTD; 90141; -.
DR   ZFIN; ZDB-GENE-050417-348; efcab11.
DR   eggNOG; KOG0027; Eukaryota.
DR   InParanoid; Q568G4; -.
DR   OrthoDB; 1435392at2759; -.
DR   PhylomeDB; Q568G4; -.
DR   PRO; PR:Q568G4; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Unplaced.
DR   GO; GO:0005509; F:calcium ion binding; IBA:GO_Central.
DR   CDD; cd00051; EFh; 1.
DR   InterPro; IPR011992; EF-hand-dom_pair.
DR   InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR   InterPro; IPR002048; EF_hand_dom.
DR   Pfam; PF13499; EF-hand_7; 1.
DR   SMART; SM00054; EFh; 3.
DR   SUPFAM; SSF47473; SSF47473; 1.
DR   PROSITE; PS00018; EF_HAND_1; 1.
DR   PROSITE; PS50222; EF_HAND_2; 3.
PE   2: Evidence at transcript level;
KW   Calcium; Metal-binding; Reference proteome; Repeat.
FT   CHAIN           1..167
FT                   /note="EF-hand calcium-binding domain-containing protein
FT                   11"
FT                   /id="PRO_0000286583"
FT   DOMAIN          17..52
FT                   /note="EF-hand 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
FT   DOMAIN          91..126
FT                   /note="EF-hand 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
FT   DOMAIN          127..162
FT                   /note="EF-hand 3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
FT   BINDING         140
FT                   /ligand="Ca(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29108"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
FT   BINDING         142
FT                   /ligand="Ca(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29108"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
FT   BINDING         144
FT                   /ligand="Ca(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29108"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
FT   BINDING         146
FT                   /ligand="Ca(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29108"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
FT   BINDING         151
FT                   /ligand="Ca(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29108"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
SQ   SEQUENCE   167 AA;  19298 MW;  915D096EB47CD1B2 CRC64;
     MLTTGRSFRN ERQINDAERK KIELVFHQCD VDKKGYMSRE DLKIAVVMLF GYKPSKSETN
     ILMENGTIRD CKGVPLEPFA TLMRRKMSAE DPYEKARQIF SAFDVHCRGF LKLDDFKSAF
     KRVAPRLQER TVLEAFRHAD QDSDGHISFK DFENIISYGL ANTCTST