EFC11_RAT
ID EFC11_RAT Reviewed; 162 AA.
AC Q6AXQ2;
DT 15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT 13-SEP-2004, sequence version 1.
DT 03-AUG-2022, entry version 113.
DE RecName: Full=EF-hand calcium-binding domain-containing protein 11;
GN Name=Efcab11;
OS Rattus norvegicus (Rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Rattus.
OX NCBI_TaxID=10116;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Testis;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BC079408; AAH79408.1; -; mRNA.
DR RefSeq; NP_001019521.1; NM_001024350.1.
DR AlphaFoldDB; Q6AXQ2; -.
DR SMR; Q6AXQ2; -.
DR BioGRID; 272013; 1.
DR STRING; 10116.ENSRNOP00000005082; -.
DR PhosphoSitePlus; Q6AXQ2; -.
DR PaxDb; Q6AXQ2; -.
DR DNASU; 500705; -.
DR Ensembl; ENSRNOT00000082444; ENSRNOP00000069648; ENSRNOG00000053317.
DR GeneID; 500705; -.
DR KEGG; rno:500705; -.
DR UCSC; RGD:1565006; rat.
DR CTD; 90141; -.
DR RGD; 1565006; Efcab11.
DR eggNOG; KOG0027; Eukaryota.
DR GeneTree; ENSGT00390000004917; -.
DR HOGENOM; CLU_114999_0_0_1; -.
DR InParanoid; Q6AXQ2; -.
DR OMA; VHYRGYL; -.
DR OrthoDB; 1435392at2759; -.
DR PhylomeDB; Q6AXQ2; -.
DR TreeFam; TF329255; -.
DR PRO; PR:Q6AXQ2; -.
DR Proteomes; UP000002494; Chromosome 6.
DR Bgee; ENSRNOG00000053317; Expressed in testis and 6 other tissues.
DR Genevisible; Q6AXQ2; RN.
DR GO; GO:0005509; F:calcium ion binding; IBA:GO_Central.
DR CDD; cd00051; EFh; 1.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR Pfam; PF13499; EF-hand_7; 1.
DR Pfam; PF13833; EF-hand_8; 1.
DR SMART; SM00054; EFh; 3.
DR SUPFAM; SSF47473; SSF47473; 1.
DR PROSITE; PS00018; EF_HAND_1; 1.
DR PROSITE; PS50222; EF_HAND_2; 3.
PE 2: Evidence at transcript level;
KW Calcium; Metal-binding; Reference proteome; Repeat.
FT CHAIN 1..162
FT /note="EF-hand calcium-binding domain-containing protein
FT 11"
FT /id="PRO_0000286582"
FT DOMAIN 18..53
FT /note="EF-hand 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
FT DOMAIN 91..126
FT /note="EF-hand 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
FT DOMAIN 127..162
FT /note="EF-hand 3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
FT BINDING 140
FT /ligand="Ca(2+)"
FT /ligand_id="ChEBI:CHEBI:29108"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
FT BINDING 142
FT /ligand="Ca(2+)"
FT /ligand_id="ChEBI:CHEBI:29108"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
FT BINDING 144
FT /ligand="Ca(2+)"
FT /ligand_id="ChEBI:CHEBI:29108"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
FT BINDING 146
FT /ligand="Ca(2+)"
FT /ligand_id="ChEBI:CHEBI:29108"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
FT BINDING 151
FT /ligand="Ca(2+)"
FT /ligand_id="ChEBI:CHEBI:29108"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
SQ SEQUENCE 162 AA; 18494 MW; F8D33566FD00D4C0 CRC64;
MFLSEAGARP RAGEISASER RKWVEVFKAC DEDNKGYLSR EDFKVAIVML FGYKPSKIEA
DAVMSSANPD TSGVSLEGFL NVVQRKKEAQ LYRNEIRHIF TAFDVHYRGF LTLEDFKRAF
SQVAPKLPSR TVLEVFREAD QDSDGHVSFR DFEYAMNHGK AK
