ID   EFCC1_BOVIN             Reviewed;         597 AA.
AC   P0CG25;
DT   13-JUL-2010, integrated into UniProtKB/Swiss-Prot.
DT   13-JUL-2010, sequence version 1.
DT   25-MAY-2022, entry version 30.
DE   RecName: Full=EF-hand and coiled-coil domain-containing protein 1;
DE   AltName: Full=Coiled-coil domain-containing protein 48;
GN   Name=EFCC1; Synonyms=CCDC48;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Hypothalamus;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; BC149957; -; NOT_ANNOTATED_CDS; mRNA.
DR   RefSeq; NP_001140164.1; NM_001146692.1.
DR   AlphaFoldDB; P0CG25; -.
DR   STRING; 9913.ENSBTAP00000007776; -.
DR   PRIDE; P0CG25; -.
DR   GeneID; 617677; -.
DR   KEGG; bta:617677; -.
DR   CTD; 79825; -.
DR   InParanoid; P0CG25; -.
DR   OrthoDB; 1061806at2759; -.
DR   Proteomes; UP000009136; Unplaced.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   InterPro; IPR031601; CCD48.
DR   InterPro; IPR002048; EF_hand_dom.
DR   Pfam; PF15799; CCD48; 1.
DR   PROSITE; PS50222; EF_HAND_2; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Reference proteome.
FT   CHAIN           1..597
FT                   /note="EF-hand and coiled-coil domain-containing protein 1"
FT                   /id="PRO_0000395325"
FT   DOMAIN          43..78
FT                   /note="EF-hand"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
FT   REGION          85..122
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          160..195
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          322..380
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          479..532
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        339..353
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   597 AA;  64552 MW;  65115BCAFE4B64BC CRC64;
     MEGAASDPYR RPARRTQWLL SALAHHYGLD RGVENEIVVL ATGLDQYLQE VFHHLDSRGA
     GRLPRADFRA LCAVLGLRFE GAAAPGEASE DTAAGDTNSG DVISGDAAAG EAAEWDEDAE
     EEARLALRAE PPELTFRQFH ARLCGYFGTR AGPRLPRGAL SEHIETQIRL RRPRRRRRRA
     ARPPGPDGGP DGERLARLEE ENSSLRELVE DLRAALQSSD ARCLALQVGL WKSQAGAQEA
     ARGEPEAAAR ELRQARGALA AAEAQAGRLR RGQAEVRRRA EEARAAVLRS LGRVRELEAL
     ARQMPGLQRG LRLLEGELRR YRSEGTQLPG PSRASPEPDT KSSEPEDGEA RGPEPPPEGA
     WGSGNSPASR PPGPARASPG LDEQLFRSVE GQAASDEEDD REKWQEAQRL PAEVTALLAG
     LSGCGSGCDD QTAKKLMTYC SHLGGANHAH TLGELETCVA MLVEQLGSRG CGAKTLRTPE
     EEAELQRKVG ENESLRQELQ MVEAERVRLS LLEEKLEDVL GLLQRLRDLN ISKKALGKIL
     LSTLDACRDP AHDGPSGPLA VLEALHRALA GCELLRREPS APASTAPALP HSFPISG