ID   EFEMO_STAAB             Reviewed;         284 AA.
AC   Q2YVG5;
DT   20-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT   20-DEC-2005, sequence version 1.
DT   25-MAY-2022, entry version 85.
DE   RecName: Full=Efem/EfeO family lipoprotein;
DE   Flags: Precursor;
GN   OrderedLocusNames=SAB0293;
OS   Staphylococcus aureus (strain bovine RF122 / ET3-1).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=273036;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=bovine RF122 / ET3-1;
RX   PubMed=17971880; DOI=10.1371/journal.pone.0001120;
RA   Herron-Olson L., Fitzgerald J.R., Musser J.M., Kapur V.;
RT   "Molecular correlates of host specialization in Staphylococcus aureus.";
RL   PLoS ONE 2:E1120-E1120(2007).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|PROSITE-
CC       ProRule:PRU00303}; Lipid-anchor {ECO:0000255|PROSITE-ProRule:PRU00303}.
CC   -!- SIMILARITY: Belongs to the EfeM/EfeO family. {ECO:0000305}.
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DR   EMBL; AJ938182; CAI79981.1; -; Genomic_DNA.
DR   RefSeq; WP_000737196.1; NC_007622.1.
DR   AlphaFoldDB; Q2YVG5; -.
DR   SMR; Q2YVG5; -.
DR   KEGG; sab:SAB0293; -.
DR   HOGENOM; CLU_050342_0_1_9; -.
DR   OMA; WTGWHRL; -.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   CDD; cd14656; Imelysin-like_EfeO; 1.
DR   Gene3D; 1.20.1420.20; -; 1.
DR   InterPro; IPR018976; Imelysin-like.
DR   InterPro; IPR034981; Imelysin-like_EfeO/Algp7.
DR   InterPro; IPR038352; Imelysin_sf.
DR   Pfam; PF09375; Peptidase_M75; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Lipoprotein; Membrane; Palmitate; Signal.
FT   SIGNAL          1..17
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   CHAIN           18..284
FT                   /note="Efem/EfeO family lipoprotein"
FT                   /id="PRO_0000278309"
FT   LIPID           18
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   LIPID           18
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
SQ   SEQUENCE   284 AA;  32247 MW;  B84CD98EB234F392 CRC64;
     MKKLTTLLLA STLLIAACGN DDSKKDDSKT SKKDDGVKAE LKQATKAYDK YTDEQLNEFL
     KGTEKFVKAI ENNDMAQAKA LYPKVRMYYE RSEPVAEAFG DLDPKIDARL ADMKEEKKEK
     EWSGYHKIEK ALYEDKKIDD VTKKDAQQLL KDAKELHAKA DTLDITPKLM LQGSVDLLNE
     VATSKITGEE EIYSHTDLYD FKANVEGAQK IYDLFKPILE KKDKKLSDDI QMNFDKVNQL
     LDKYKDNNGG YESFEKVSKK DRKAFADAVN ALGEPLSKMA VITE