ID   EFEMO_STAHJ             Reviewed;         287 AA.
AC   Q4L8N2;
DT   20-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT   02-AUG-2005, sequence version 1.
DT   25-MAY-2022, entry version 102.
DE   RecName: Full=Efem/EfeO family lipoprotein;
DE   Flags: Precursor;
GN   OrderedLocusNames=SH0684;
OS   Staphylococcus haemolyticus (strain JCSC1435).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=279808;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCSC1435;
RX   PubMed=16237012; DOI=10.1128/jb.187.21.7292-7308.2005;
RA   Takeuchi F., Watanabe S., Baba T., Yuzawa H., Ito T., Morimoto Y.,
RA   Kuroda M., Cui L., Takahashi M., Ankai A., Baba S., Fukui S., Lee J.C.,
RA   Hiramatsu K.;
RT   "Whole-genome sequencing of Staphylococcus haemolyticus uncovers the
RT   extreme plasticity of its genome and the evolution of human-colonizing
RT   staphylococcal species.";
RL   J. Bacteriol. 187:7292-7308(2005).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|PROSITE-
CC       ProRule:PRU00303}; Lipid-anchor {ECO:0000255|PROSITE-ProRule:PRU00303}.
CC   -!- SIMILARITY: Belongs to the EfeM/EfeO family. {ECO:0000305}.
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DR   EMBL; AP006716; BAE03993.1; -; Genomic_DNA.
DR   RefSeq; WP_011275009.1; NC_007168.1.
DR   AlphaFoldDB; Q4L8N2; -.
DR   SMR; Q4L8N2; -.
DR   STRING; 279808.SH0684; -.
DR   EnsemblBacteria; BAE03993; BAE03993; SH0684.
DR   GeneID; 58063127; -.
DR   KEGG; sha:SH0684; -.
DR   eggNOG; COG2822; Bacteria.
DR   HOGENOM; CLU_050342_0_1_9; -.
DR   OMA; WTGWHRL; -.
DR   OrthoDB; 1430947at2; -.
DR   Proteomes; UP000000543; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   CDD; cd14656; Imelysin-like_EfeO; 1.
DR   Gene3D; 1.20.1420.20; -; 1.
DR   InterPro; IPR018976; Imelysin-like.
DR   InterPro; IPR034981; Imelysin-like_EfeO/Algp7.
DR   InterPro; IPR038352; Imelysin_sf.
DR   Pfam; PF09375; Peptidase_M75; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Lipoprotein; Membrane; Palmitate; Signal.
FT   SIGNAL          1..17
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   CHAIN           18..287
FT                   /note="Efem/EfeO family lipoprotein"
FT                   /id="PRO_0000278318"
FT   REGION          20..50
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   LIPID           18
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   LIPID           18
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
SQ   SEQUENCE   287 AA;  32407 MW;  B1E19198FD6A4C4C CRC64;
     MKKLPTILLA SSLLLAACGN NSHSDDNSNK DKQSQSSKGE NKASLQKATK EYEKYTDGQL
     DKFLDGTEKF VAAIKADDMD KAKELYPKVR MYYERSEPVA EAFGDLDPKI DARLADMKEE
     KKEDQWTGYH KIEKSLYQDN KIDETTKKDA DQLLKDAKEL DAKADTLDIT PKLMLQGSVD
     LLNEVSTSKI TGEEEIYSHT DLYDFKANIE GAQKIYELFK PELNKKDKKL SADIQKNFDK
     VNQLLDKYKD GDGFKDYSAV TKEDRKALSD AVNSLGEPLS KMAVVTE