ID   EFEO_ECOL5              Reviewed;         375 AA.
AC   Q0TJ49;
DT   20-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT   05-SEP-2006, sequence version 1.
DT   25-MAY-2022, entry version 83.
DE   RecName: Full=Iron uptake system component EfeO;
DE   Flags: Precursor;
GN   Name=efeO; OrderedLocusNames=ECP_1017;
OS   Escherichia coli O6:K15:H31 (strain 536 / UPEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=362663;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=536 / UPEC;
RX   PubMed=16879640; DOI=10.1111/j.1365-2958.2006.05255.x;
RA   Hochhut B., Wilde C., Balling G., Middendorf B., Dobrindt U.,
RA   Brzuszkiewicz E., Gottschalk G., Carniel E., Hacker J.;
RT   "Role of pathogenicity island-associated integrases in the genome
RT   plasticity of uropathogenic Escherichia coli strain 536.";
RL   Mol. Microbiol. 61:584-595(2006).
CC   -!- FUNCTION: Involved in Fe(2+) uptake. Could be an iron-binding and/or
CC       electron-transfer component (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Monomer. Part of a ferrous iron transporter composed of EfeU,
CC       EfeO and EfeB (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the EfeM/EfeO family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000247; ABG69030.1; -; Genomic_DNA.
DR   RefSeq; WP_000154419.1; NC_008253.1.
DR   AlphaFoldDB; Q0TJ49; -.
DR   SMR; Q0TJ49; -.
DR   STRING; 362663.ECP_1017; -.
DR   EnsemblBacteria; ABG69030; ABG69030; ECP_1017.
DR   KEGG; ecp:ECP_1017; -.
DR   HOGENOM; CLU_050342_2_1_6; -.
DR   OMA; WTGWHRL; -.
DR   Proteomes; UP000009182; Chromosome.
DR   GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR   CDD; cd14656; Imelysin-like_EfeO; 1.
DR   Gene3D; 1.20.1420.20; -; 1.
DR   Gene3D; 2.60.40.420; -; 1.
DR   InterPro; IPR008972; Cupredoxin.
DR   InterPro; IPR028096; EfeO_Cupredoxin.
DR   InterPro; IPR018976; Imelysin-like.
DR   InterPro; IPR034981; Imelysin-like_EfeO/Algp7.
DR   InterPro; IPR038352; Imelysin_sf.
DR   Pfam; PF13473; Cupredoxin_1; 1.
DR   Pfam; PF09375; Peptidase_M75; 1.
DR   SUPFAM; SSF49503; SSF49503; 1.
PE   3: Inferred from homology;
KW   Periplasm; Signal.
FT   SIGNAL          1..26
FT                   /evidence="ECO:0000255"
FT   CHAIN           27..375
FT                   /note="Iron uptake system component EfeO"
FT                   /id="PRO_0000278557"
SQ   SEQUENCE   375 AA;  41137 MW;  6CB1E1AB83C3B8B6 CRC64;
     MTINFRRNAL QVSVAALFSS AFMANAADIP QVKVTVTDKQ CEPMTITVNA GKTQFIIQNH
     SQKALEWEIL KGVMVVEERE NIAPGFSQKM TANLQPGEYD MTCGLLTNPK GKLIVKGEAT
     ADAAQSDALL SLGGAITAYK AYVMAETTQL VTDTKAFTDA IKAGDIEKAK ALYAPTRQHY
     ERIEPIAELF SDLDGSIDAR EDDYEQKAAD PKFTGFHRLE KALFGDNTTK GMDKYADQLY
     TDVVDLQKRI SELAFPPSKV VGGAAGLIEE VAASKISGEE DRYSHTDLWD FQANVEGSQK
     IVDLLRPQLQ KANPELLAKV DANFKKVDTI LAKYRTKDGF ENYDKLTDAD RNALKGPITA
     LAEDLAQLRG VLGLD