EFEO_SHIFL
ID EFEO_SHIFL Reviewed; 375 AA.
AC P0AB25; P75902; Q9R2S4;
DT 11-OCT-2005, integrated into UniProtKB/Swiss-Prot.
DT 11-OCT-2005, sequence version 1.
DT 25-MAY-2022, entry version 101.
DE RecName: Full=Iron uptake system component EfeO;
DE Flags: Precursor;
GN Name=efeO; OrderedLocusNames=SF1020, S1090;
OS Shigella flexneri.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Shigella.
OX NCBI_TaxID=623;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=301 / Serotype 2a;
RX PubMed=12384590; DOI=10.1093/nar/gkf566;
RA Jin Q., Yuan Z., Xu J., Wang Y., Shen Y., Lu W., Wang J., Liu H., Yang J.,
RA Yang F., Zhang X., Zhang J., Yang G., Wu H., Qu D., Dong J., Sun L.,
RA Xue Y., Zhao A., Gao Y., Zhu J., Kan B., Ding K., Chen S., Cheng H.,
RA Yao Z., He B., Chen R., Ma D., Qiang B., Wen Y., Hou Y., Yu J.;
RT "Genome sequence of Shigella flexneri 2a: insights into pathogenicity
RT through comparison with genomes of Escherichia coli K12 and O157.";
RL Nucleic Acids Res. 30:4432-4441(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700930 / 2457T / Serotype 2a;
RX PubMed=12704152; DOI=10.1128/iai.71.5.2775-2786.2003;
RA Wei J., Goldberg M.B., Burland V., Venkatesan M.M., Deng W., Fournier G.,
RA Mayhew G.F., Plunkett G. III, Rose D.J., Darling A., Mau B., Perna N.T.,
RA Payne S.M., Runyen-Janecky L.J., Zhou S., Schwartz D.C., Blattner F.R.;
RT "Complete genome sequence and comparative genomics of Shigella flexneri
RT serotype 2a strain 2457T.";
RL Infect. Immun. 71:2775-2786(2003).
CC -!- FUNCTION: Involved in Fe(2+) uptake. Could be an iron-binding and/or
CC electron-transfer component (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Monomer. Part of a ferrous iron transporter composed of EfeU,
CC EfeO and EfeB (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the EfeM/EfeO family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AE005674; AAN42646.1; -; Genomic_DNA.
DR EMBL; AE014073; AAP16531.1; -; Genomic_DNA.
DR RefSeq; NP_706939.1; NC_004337.2.
DR RefSeq; WP_000154398.1; NZ_WPGW01000205.1.
DR AlphaFoldDB; P0AB25; -.
DR SMR; P0AB25; -.
DR STRING; 198214.SF1020; -.
DR PRIDE; P0AB25; -.
DR EnsemblBacteria; AAN42646; AAN42646; SF1020.
DR EnsemblBacteria; AAP16531; AAP16531; S1090.
DR GeneID; 1023982; -.
DR GeneID; 58462582; -.
DR KEGG; sfl:SF1020; -.
DR KEGG; sfx:S1090; -.
DR PATRIC; fig|198214.7.peg.1184; -.
DR HOGENOM; CLU_050342_2_1_6; -.
DR OMA; WTGWHRL; -.
DR OrthoDB; 1430947at2; -.
DR Proteomes; UP000001006; Chromosome.
DR Proteomes; UP000002673; Chromosome.
DR GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR CDD; cd14656; Imelysin-like_EfeO; 1.
DR Gene3D; 1.20.1420.20; -; 1.
DR Gene3D; 2.60.40.420; -; 1.
DR InterPro; IPR008972; Cupredoxin.
DR InterPro; IPR028096; EfeO_Cupredoxin.
DR InterPro; IPR018976; Imelysin-like.
DR InterPro; IPR034981; Imelysin-like_EfeO/Algp7.
DR InterPro; IPR038352; Imelysin_sf.
DR Pfam; PF13473; Cupredoxin_1; 1.
DR Pfam; PF09375; Peptidase_M75; 1.
DR SUPFAM; SSF49503; SSF49503; 1.
PE 3: Inferred from homology;
KW Periplasm; Reference proteome; Signal.
FT SIGNAL 1..26
FT /evidence="ECO:0000255"
FT CHAIN 27..375
FT /note="Iron uptake system component EfeO"
FT /id="PRO_0000168805"
SQ SEQUENCE 375 AA; 41138 MW; A3CA2A106A58F09F CRC64;
MTINFRRNAL QLSVAALFSS AFMANAADVP QVKVTVTDKQ CEPMTITVNA GKTQFIIQNH
SQKALEWEIL KGVMVVEERE NIAPGFSQKM TANLQPGEYD MTCGLLTNPK GKLIVKGEAT
ADAAQSDALL SLGGAITAYK AYVMAETTQL VTDTKAFTDA IKAGDIEKAK ALYAPTRQHY
ERIEPIAELF SDLDGSIDAR EDDYEQKAAD PKFTGFHRLE KALFGDNTTK GMDQYAEQLY
TDVVDLQKRI SELAFPPSKV VGGAAGLIEE VAASKISGEE DRYSHTDLWD FQANVEGSQK
IVDLLRPQLQ KANPELLAKV DANFKKVDTI LAKYRTKDGF ETYDKLTDAD RNALKGPITA
LAEDLAQLRG VLGLD
