ID   EFEO_YERPN              Reviewed;         376 AA.
AC   Q1CHD4; C4GUG0;
DT   20-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT   11-JUL-2006, sequence version 1.
DT   25-MAY-2022, entry version 77.
DE   RecName: Full=Iron uptake system component EfeO;
DE   Flags: Precursor;
GN   Name=efeO; OrderedLocusNames=YPN_2268; ORFNames=YP516_2549;
OS   Yersinia pestis bv. Antiqua (strain Nepal516).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=377628;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Nepal516;
RX   PubMed=16740952; DOI=10.1128/jb.00124-06;
RA   Chain P.S.G., Hu P., Malfatti S.A., Radnedge L., Larimer F., Vergez L.M.,
RA   Worsham P., Chu M.C., Andersen G.L.;
RT   "Complete genome sequence of Yersinia pestis strains Antiqua and Nepal516:
RT   evidence of gene reduction in an emerging pathogen.";
RL   J. Bacteriol. 188:4453-4463(2006).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Nepal516;
RA   Plunkett G. III, Anderson B.D., Baumler D.J., Burland V., Cabot E.L.,
RA   Glasner J.D., Mau B., Neeno-Eckwall E., Perna N.T., Munk A.C., Tapia R.,
RA   Green L.D., Rogers Y.C., Detter J.C., Bruce D.C., Brettin T.S.;
RT   "Yersinia pestis Nepal516A whole genome shotgun sequencing project.";
RL   Submitted (APR-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in Fe(2+) uptake. Could be an iron-binding and/or
CC       electron-transfer component (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Monomer. Part of a ferrous iron transporter composed of EfeU,
CC       EfeO and EfeB (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the EfeM/EfeO family. {ECO:0000305}.
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DR   EMBL; CP000305; ABG18596.1; -; Genomic_DNA.
DR   EMBL; ACNQ01000013; EEO76347.1; -; Genomic_DNA.
DR   RefSeq; WP_002211166.1; NZ_ACNQ01000013.1.
DR   AlphaFoldDB; Q1CHD4; -.
DR   SMR; Q1CHD4; -.
DR   EnsemblBacteria; ABG18596; ABG18596; YPN_2268.
DR   GeneID; 57976726; -.
DR   KEGG; ypn:YPN_2268; -.
DR   HOGENOM; CLU_050342_2_1_6; -.
DR   OMA; WTGWHRL; -.
DR   Proteomes; UP000008936; Chromosome.
DR   GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR   CDD; cd14656; Imelysin-like_EfeO; 1.
DR   Gene3D; 1.20.1420.20; -; 1.
DR   Gene3D; 2.60.40.420; -; 1.
DR   InterPro; IPR008972; Cupredoxin.
DR   InterPro; IPR028096; EfeO_Cupredoxin.
DR   InterPro; IPR018976; Imelysin-like.
DR   InterPro; IPR034981; Imelysin-like_EfeO/Algp7.
DR   InterPro; IPR038352; Imelysin_sf.
DR   Pfam; PF13473; Cupredoxin_1; 1.
DR   Pfam; PF09375; Peptidase_M75; 1.
DR   SUPFAM; SSF49503; SSF49503; 1.
PE   3: Inferred from homology;
KW   Periplasm; Signal.
FT   SIGNAL          1..27
FT                   /evidence="ECO:0000255"
FT   CHAIN           28..376
FT                   /note="Iron uptake system component EfeO"
FT                   /id="PRO_0000278562"
SQ   SEQUENCE   376 AA;  41353 MW;  19B8FA8B86165ACB CRC64;
     MSIWFFRRTA LHAALLSLPV FAISAQAADI QQVKITVNDK QCEPMALTVP AGKTQFIVHN
     VSQKGLEWEI LKGVMVVEER ENIAPGFTQK MTANLEPGEY DMTCGLLSNP KGKLTVTVAA
     GEQAPVKPDA MALVGPIAEY KVYVTQEVAQ LVSQTKAFTD AVKAGDLALA RKLYAPTRQH
     YERIEPIAEL FSDLDGSIDA REDDFEQKSA DPKFTGFHRL EKILFGDNTT KGADKFADLL
     YQDTLELQKR IAGLTFAPNK VVGGAAGLIE EVAASKISGE EDRYSRTDLW DFQANVDGAQ
     KIVNLLRPLL EKADKPLLQK IDANFNTVDS VLAKYRTKEG YESYEKLTDA DRNAMKGPIT
     ALAEDLAQLR GVLGLD