ID   EFG1P_ASPFU             Reviewed;         319 AA.
AC   Q4WI71;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2005, sequence version 1.
DT   03-AUG-2022, entry version 71.
DE   RecName: Full=rRNA-processing protein efg1;
GN   Name=efg1; ORFNames=AFUA_2G02870;
OS   Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC
OS   A1100) (Aspergillus fumigatus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Fumigati.
OX   NCBI_TaxID=330879;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100;
RX   PubMed=16372009; DOI=10.1038/nature04332;
RA   Nierman W.C., Pain A., Anderson M.J., Wortman J.R., Kim H.S., Arroyo J.,
RA   Berriman M., Abe K., Archer D.B., Bermejo C., Bennett J.W., Bowyer P.,
RA   Chen D., Collins M., Coulsen R., Davies R., Dyer P.S., Farman M.L.,
RA   Fedorova N., Fedorova N.D., Feldblyum T.V., Fischer R., Fosker N.,
RA   Fraser A., Garcia J.L., Garcia M.J., Goble A., Goldman G.H., Gomi K.,
RA   Griffith-Jones S., Gwilliam R., Haas B.J., Haas H., Harris D.E.,
RA   Horiuchi H., Huang J., Humphray S., Jimenez J., Keller N., Khouri H.,
RA   Kitamoto K., Kobayashi T., Konzack S., Kulkarni R., Kumagai T., Lafton A.,
RA   Latge J.-P., Li W., Lord A., Lu C., Majoros W.H., May G.S., Miller B.L.,
RA   Mohamoud Y., Molina M., Monod M., Mouyna I., Mulligan S., Murphy L.D.,
RA   O'Neil S., Paulsen I., Penalva M.A., Pertea M., Price C., Pritchard B.L.,
RA   Quail M.A., Rabbinowitsch E., Rawlins N., Rajandream M.A., Reichard U.,
RA   Renauld H., Robson G.D., Rodriguez de Cordoba S., Rodriguez-Pena J.M.,
RA   Ronning C.M., Rutter S., Salzberg S.L., Sanchez M., Sanchez-Ferrero J.C.,
RA   Saunders D., Seeger K., Squares R., Squares S., Takeuchi M., Tekaia F.,
RA   Turner G., Vazquez de Aldana C.R., Weidman J., White O., Woodward J.R.,
RA   Yu J.-H., Fraser C.M., Galagan J.E., Asai K., Machida M., Hall N.,
RA   Barrell B.G., Denning D.W.;
RT   "Genomic sequence of the pathogenic and allergenic filamentous fungus
RT   Aspergillus fumigatus.";
RL   Nature 438:1151-1156(2005).
CC   -!- FUNCTION: Involved in rRNA processing. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the EFG1 family. {ECO:0000305}.
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DR   EMBL; AAHF01000008; EAL87384.1; -; Genomic_DNA.
DR   RefSeq; XP_749422.1; XM_744329.1.
DR   AlphaFoldDB; Q4WI71; -.
DR   SMR; Q4WI71; -.
DR   STRING; 746128.CADAFUBP00001948; -.
DR   PRIDE; Q4WI71; -.
DR   EnsemblFungi; EAL87384; EAL87384; AFUA_2G02870.
DR   GeneID; 3506999; -.
DR   KEGG; afm:AFUA_2G02870; -.
DR   VEuPathDB; FungiDB:Afu2g02870; -.
DR   eggNOG; KOG4484; Eukaryota.
DR   HOGENOM; CLU_066912_0_0_1; -.
DR   InParanoid; Q4WI71; -.
DR   OMA; KCMEEKT; -.
DR   OrthoDB; 1514264at2759; -.
DR   Proteomes; UP000002530; Chromosome 2.
DR   GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR   GO; GO:0030688; C:preribosome, small subunit precursor; IBA:GO_Central.
DR   GO; GO:0000462; P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:GO_Central.
DR   InterPro; IPR019310; Efg1.
DR   Pfam; PF10153; Efg1; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Nucleus; Reference proteome; rRNA processing.
FT   CHAIN           1..319
FT                   /note="rRNA-processing protein efg1"
FT                   /id="PRO_0000330260"
FT   REGION          1..52
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          181..204
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          230..319
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          49..131
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        1..35
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        181..195
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        230..293
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   319 AA;  36558 MW;  332D96BBFF639944 CRC64;
     MPREFSREKR AHSDSTTTSK RKYHEGSEDS QPAKKKKVHP PKHEHNYPSV NELKKRIRDV
     KRLLNRVDLP ADARIVQERA LAGYEKDLED ELARRHRSQM IKKYHFVRFL DRKAASKDLK
     RLLRREQEIS NSDLDPAAKK EKLAALAGKI HAAQVNHNYT IYYPLTQKYV ALYAEQKKKK
     KESSAQSEKP SEPEAEVASK LIYDTTGERP PMWRVVEKCM EDGTLDLLRE GKLDGSEKGE
     KSSQAPEQKK SKKSTDDDQY ARNKSSTEKV SDKPSGKSRK SGGKQDRKPK RSAAMEGAYW
     SANEHDDDDI ESDGGFFEA