ID   EFG1P_CANAL             Reviewed;         237 AA.
AC   Q5AK42; A0A1D8PP46;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   26-APR-2005, sequence version 1.
DT   03-AUG-2022, entry version 76.
DE   RecName: Full=rRNA-processing protein EFG1;
GN   OrderedLocusNames=CAALFM_C504910WA; ORFNames=CaO19.11461, CaO19.3978;
OS   Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX   NCBI_TaxID=237561;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=15123810; DOI=10.1073/pnas.0401648101;
RA   Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B.,
RA   Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W.,
RA   Scherer S.;
RT   "The diploid genome sequence of Candida albicans.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=17419877; DOI=10.1186/gb-2007-8-4-r52;
RA   van het Hoog M., Rast T.J., Martchenko M., Grindle S., Dignard D.,
RA   Hogues H., Cuomo C., Berriman M., Scherer S., Magee B.B., Whiteway M.,
RA   Chibana H., Nantel A., Magee P.T.;
RT   "Assembly of the Candida albicans genome into sixteen supercontigs aligned
RT   on the eight chromosomes.";
RL   Genome Biol. 8:RESEARCH52.1-RESEARCH52.12(2007).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=24025428; DOI=10.1186/gb-2013-14-9-r97;
RA   Muzzey D., Schwartz K., Weissman J.S., Sherlock G.;
RT   "Assembly of a phased diploid Candida albicans genome facilitates allele-
RT   specific measurements and provides a simple model for repeat and indel
RT   structure.";
RL   Genome Biol. 14:RESEARCH97.1-RESEARCH97.14(2013).
CC   -!- FUNCTION: Involved in rRNA processing. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the EFG1 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP017627; AOW29895.1; -; Genomic_DNA.
DR   RefSeq; XP_721887.1; XM_716794.1.
DR   AlphaFoldDB; Q5AK42; -.
DR   SMR; Q5AK42; -.
DR   STRING; 237561.Q5AK42; -.
DR   GeneID; 3636417; -.
DR   KEGG; cal:CAALFM_C504910WA; -.
DR   CGD; CAL0000198404; orf19.11461.
DR   VEuPathDB; FungiDB:C5_04910W_A; -.
DR   eggNOG; KOG4484; Eukaryota.
DR   HOGENOM; CLU_066912_2_0_1; -.
DR   InParanoid; Q5AK42; -.
DR   OMA; HMIRFFE; -.
DR   OrthoDB; 1514264at2759; -.
DR   PRO; PR:Q5AK42; -.
DR   Proteomes; UP000000559; Chromosome 5.
DR   GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR   GO; GO:0030688; C:preribosome, small subunit precursor; IBA:GO_Central.
DR   GO; GO:0000462; P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:GO_Central.
DR   InterPro; IPR019310; Efg1.
DR   Pfam; PF10153; Efg1; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Nucleus; Reference proteome; rRNA processing.
FT   CHAIN           1..237
FT                   /note="rRNA-processing protein EFG1"
FT                   /id="PRO_0000330265"
FT   REGION          1..24
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          206..237
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          53..113
FT                   /evidence="ECO:0000255"
FT   COILED          166..186
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        1..18
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        206..222
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        223..237
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   237 AA;  27761 MW;  603037859D91C102 CRC64;
     MPKTVKNPKN NKSRSRGAPI QVAESIGSGS AKIKKKIRDI ERLIKKNPNL PADKKIEYDR
     ALKGLKVELQ NSQVQNKAKV LAKKYHMVRF FERKKAVRKL KNLRKEFERI SQTGIRKDIK
     KARKQLRHGE IDLAYVILFP KTEKYISLYP SPNDEDQTDP NVIKGLKITE ERRREFRKYI
     EKLMEEGKLP FSIDDALQGK NIRLDNDKTQ KAVLTEEIDA PEQKQDEQQE EQDDFFE