ID   EFG1P_CRYNB             Reviewed;         286 AA.
AC   P0CN35; Q55HI6; Q5K724;
DT   28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT   28-JUN-2011, sequence version 1.
DT   25-MAY-2022, entry version 26.
DE   RecName: Full=rRNA-processing protein EFG1;
GN   Name=EFG1; OrderedLocusNames=CNBN1340;
OS   Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)
OS   (Filobasidiella neoformans).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC   Tremellales; Cryptococcaceae; Cryptococcus;
OC   Cryptococcus neoformans species complex.
OX   NCBI_TaxID=283643;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=B-3501A;
RX   PubMed=15653466; DOI=10.1126/science.1103773;
RA   Loftus B.J., Fung E., Roncaglia P., Rowley D., Amedeo P., Bruno D.,
RA   Vamathevan J., Miranda M., Anderson I.J., Fraser J.A., Allen J.E.,
RA   Bosdet I.E., Brent M.R., Chiu R., Doering T.L., Donlin M.J., D'Souza C.A.,
RA   Fox D.S., Grinberg V., Fu J., Fukushima M., Haas B.J., Huang J.C.,
RA   Janbon G., Jones S.J.M., Koo H.L., Krzywinski M.I., Kwon-Chung K.J.,
RA   Lengeler K.B., Maiti R., Marra M.A., Marra R.E., Mathewson C.A.,
RA   Mitchell T.G., Pertea M., Riggs F.R., Salzberg S.L., Schein J.E.,
RA   Shvartsbeyn A., Shin H., Shumway M., Specht C.A., Suh B.B., Tenney A.,
RA   Utterback T.R., Wickes B.L., Wortman J.R., Wye N.H., Kronstad J.W.,
RA   Lodge J.K., Heitman J., Davis R.W., Fraser C.M., Hyman R.W.;
RT   "The genome of the basidiomycetous yeast and human pathogen Cryptococcus
RT   neoformans.";
RL   Science 307:1321-1324(2005).
CC   -!- FUNCTION: Involved in rRNA processing. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the EFG1 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=EAL17307.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AAEY01000066; EAL17307.1; ALT_SEQ; Genomic_DNA.
DR   RefSeq; XP_771954.1; XM_766861.1.
DR   AlphaFoldDB; P0CN35; -.
DR   SMR; P0CN35; -.
DR   EnsemblFungi; AAW47082; AAW47082; CNN01370.
DR   EnsemblFungi; EAL17307; EAL17307; CNBN1340.
DR   GeneID; 4939744; -.
DR   KEGG; cnb:CNBN1340; -.
DR   HOGENOM; CLU_066912_2_0_1; -.
DR   Proteomes; UP000001435; Chromosome 14.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR   InterPro; IPR019310; Efg1.
DR   Pfam; PF10153; Efg1; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Nucleus; rRNA processing.
FT   CHAIN           1..286
FT                   /note="rRNA-processing protein EFG1"
FT                   /id="PRO_0000410071"
FT   REGION          1..57
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          167..213
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          259..286
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          53..103
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   286 AA;  32500 MW;  3E4275183FA5E679 CRC64;
     MPADKKQRKG AHPYRKPRPN PSDPSSSDKP ARPKPTHRIP ATEARDGAGI PGLSKLKSSI
     RQTKRLLAKE NLEPGLRVST QRRLTSLEAD LAAAERREVE RKNGAKYHKV KFFERQKLVR
     LIKRFKRKLL DSETSSKKRS KHEEELLDAR IMLNYVLHYP NTQKYISLFP SNPNQTEDED
     DDDDSSKPKL KLPPLLHPVP STEECEKMDK PTKRRYDLLL ETKRLMEESK LKSEPETDLK
     KGQVDGVVVG LGADVQIGLG DKKEAKQNAA QGTGEEEDDF FESGDE